PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassicaceae incertae sedis; Schrenkiella

Family

HD-ZIP

Protein Properties

Length: 279aa MW: 31319.3 Da PI: 8.2234

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Tp7g16730	genome	thellungiella	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	60	3.7e-19	133	187	2	56
T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 rk+ +++k+q +Le+ F+++++++ +++ LAkklgLt rqV vWFqNrRa+ k Tp7g16730 133 RKKLRLSKDQSAVLEDTFKEHNTLNPKQKLALAKKLGLTARQVEVWFQNRRARTK 187 677889***********************************************98 PP
2	HD-ZIP_I/II	122.8	1.6e-39	133	222	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreel 91 +kk+rlsk+q+++LE++F+e+++L+p++K +la++Lgl++rqv+vWFqnrRARtk+kq+E+d+e+Lkr++++l+een+rLeke +eLr +l Tp7g16730 133 RKKLRLSKDQSAVLEDTFKEHNTLNPKQKLALAKKLGLTARQVEVWFQNRRARTKLKQTEVDCEYLKRCVEKLTEENRRLEKEAAELR-AL 222 69*************************************************************************************9.54 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04618	2.6E-25	2	98	IPR006712	HD-ZIP protein, N-terminal
Gene3D	G3DSA:1.10.10.60	2.8E-18	114	187	IPR009057	Homeodomain-like
SuperFamily	SSF46689	1.09E-18	119	190	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.135	129	189	IPR001356	Homeobox domain
SMART	SM00389	1.9E-17	131	193	IPR001356	Homeobox domain
Pfam	PF00046	1.5E-16	133	187	IPR001356	Homeobox domain
CDD	cd00086	3.02E-16	133	190	No hit	No description
PRINTS	PR00031	7.3E-6	160	169	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	164	187	IPR017970	Homeobox, conserved site
PRINTS	PR00031	7.3E-6	169	185	IPR000047	Helix-turn-helix motif
SMART	SM00340	1.6E-23	189	232	IPR003106	Leucine zipper, homeobox-associated
Pfam	PF02183	7.9E-8	189	223	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010582	Biological Process	floral meristem determinacy
GO:0048467	Biological Process	gynoecium development
GO:0080127	Biological Process	fruit septum development
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0043621	Molecular Function	protein self-association

Sequence ? help Back to Top
Protein Sequence Length: 279 aa Download sequence Send to blast
MMMGKEDMGL NLSLGFAQNH PPLELNLKLT SSPMSNLQRF PWNQTFVSSS DHQNQQFLRK 60 IDVNSLPSTV DLEEETGVSS PNSTISSTVS GKRRSEREGT SGGGGDDLDI TLDRSSSRGT 120 SDEEEEYGGE ACRKKLRLSK DQSAVLEDTF KEHNTLNPKQ KLALAKKLGL TARQVEVWFQ 180 NRRARTKLKQ TEVDCEYLKR CVEKLTEENR RLEKEAAELR ALKLSPRLYG PMSPPTTLLM 240 CPSCERVAGP SNHNQRSVSL SPWLQMAHGS TFDVMHPRP

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	181	189	RRARTKLKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00050	PBM	Transfer from AT4G17460	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Tp7g16730

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AJ441252	0.0	AJ441252.1 Arabidopsis thaliana mRNA for homeodomain-leucine zipper protein HAT1.
GenBank	AK228587	0.0	AK228587.1 Arabidopsis thaliana mRNA for homeobox-leucine zipper protein HAT1, complete cds, clone: RAFL15-36-J21.
GenBank	ATU09332	0.0	U09332.1 Arabidopsis thaliana clone HAT1 homeobox protein mRNA, complete cds.
GenBank	AY087322	0.0	AY087322.1 Arabidopsis thaliana clone 34167 mRNA, complete sequence.
GenBank	BT005756	0.0	BT005756.1 Arabidopsis thaliana clone RAFL15-36-J21 (R50164) putative homeobox-leucine zipper protein HAT1 (HD-Zip protein 1) (At4g17460) mRNA, complete cds.
GenBank	BT006112	0.0	BT006112.1 Arabidopsis thaliana clone U50164 putative homeobox-leucine zipper protein HAT1 (HD-Zip protein 1) (At4g17460) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013595686.1	0.0	PREDICTED: homeobox-leucine zipper protein HAT1
Swissprot	P46600	0.0	HAT1_ARATH; Homeobox-leucine zipper protein HAT1
TrEMBL	A0A1J3FTB7	0.0	A0A1J3FTB7_NOCCA; Homeobox-leucine zipper protein HAT1
STRING	Bo7g105120.1	0.0	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1563	26	90

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G17460.1	1e-147	Homeobox-leucine zipper protein 4 (HB-4) / HD-ZIP protein

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zou LJ, et al. Role of Transcription Factor HAT1 in Modulating Arabidopsis thaliana Response to Cucumber mosaic virus. Plant Cell Physiol., 2016. 57(9): p. 1879-89 [PMID:27328697] Lozano-Sotomayor P, et al. Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana. Plant J., 2016. 88(3): p. 437-451 [PMID:27402171] Tan W, et al. Transcription factor HAT1 is a substrate of SnRK2.3 kinase and negatively regulates ABA synthesis and signaling in Arabidopsis responding to drought. PLoS Genet., 2018. 14(4): p. e1007336 [PMID:29659577]