PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassicaceae incertae sedis; Schrenkiella

Family

TCP

Protein Properties

Length: 331aa MW: 35219.3 Da PI: 7.785

Description

TCP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Tp5g24820	genome	thellungiella	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	TCP	136.1	3.1e-42	54	177	2	113
TCP 2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgtssssasec.eaesssssasnsssg...........k 89 ++k+++++++hTkv+gR+RR+R++a caar+F+L++eLG+++d++tieWLlqqa+pa++++tgt++++a+++ + s +ss s+ s++ + Tp5g24820 54 PPKRTSTKDRHTKVEGRGRRIRMPAMCAARVFQLTRELGHKSDGETIEWLLQQAEPAVIAATGTGTIPANFTsLNISLRSSRSSLSAAhlrttpssyyfH 153 789******************************************************************9997555555555533333444556666553 PP TCP 90 aaksaakskksqksaasalnlake 113 + + ++++++ q+++ n +++ Tp5g24820 154 SPTMTHHHHQHQHHQVRPKNESHS 177 333333222222222222222222 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF03634	2.5E-41	58	180	IPR005333	Transcription factor, TCP
PROSITE profile	PS51369	28.008	60	114	IPR017887	Transcription factor TCP subgroup

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0007623	Biological Process	circadian rhythm
GO:0008283	Biological Process	cell proliferation
GO:0009735	Biological Process	response to cytokinin
GO:0010229	Biological Process	inflorescence development
GO:0010252	Biological Process	auxin homeostasis
GO:0031540	Biological Process	regulation of anthocyanin biosynthetic process
GO:0042023	Biological Process	DNA endoreduplication
GO:0048467	Biological Process	gynoecium development

Sequence ? help Back to Top
Protein Sequence Length: 331 aa Download sequence Send to blast
MDPDPDHNQN HHRPNFPLQL LDSSSSSSTS LAIIPSASSS EPNSDPNSLS KKPPPKRTST 60 KDRHTKVEGR GRRIRMPAMC AARVFQLTRE LGHKSDGETI EWLLQQAEPA VIAATGTGTI 120 PANFTSLNIS LRSSRSSLSA AHLRTTPSSY YFHSPTMTHH HHQHQHHQVR PKNESHSSSS 180 SQLLDHNQMG NYLVQSTAGS LPTSQTPATA PFWSSGDNTQ NLWAFNINPH HSGDVYNTSG 240 GGGGGGGVGA AGGGGVHLMN FAAPIALFSG QPLASGYGGG GGVGGGEHNH YGVLAALNAA 300 YRPVQETPNQ QNRDGDHHHN HQEDGSTSHH S

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved the regulation of plant development. Together with TCP14, modulates plant stature by promoting cell division in young internodes. Represses cell proliferation in developing leaf blade and specific floral tissues (PubMed:21668538). Together with TCP15, acts downstream of gibberellin (GA), and the stratification pathways that promote seed germination. Involved in the control of cell proliferation at the root apical meristem (RAM) by regulating the activity of CYCB1-1 (PubMed:25655823). Acts together with SPY to promote cytokinin responses that affect leaf shape and trichome development in flowers (PubMed:22267487). Involved in gynoecium and silique development. Modulates the development of the different tissues of the gynoecium through its participation in auxin and cytokinin responses. Modulates the expression of the cytokinin-responsive genes ARR7 and ARR15. May repress the expression of the auxin biosynthetic genes YUC1 and YUC4 (PubMed:26303297). Acts as negative regulator of anthocyanin accumulation under high light conditions. Modulates the expression of transcription factors involved in the induction of anthocyanin biosynthesis genes (PubMed:26574599). Transcription factor involved in the regulation of endoreduplication. Represses endoreduplication by activating the gene expression of the key cell-cycle regulators RBR1 and CYCA2-3 (PubMed:25757472). Regulates the expression of the defense gene pathogenesis-related protein 2 (PR2) in antagonism to SRFR1, a negative regulator of effector-triggered immunity (PubMed:24689742). {ECO:0000269\|PubMed:21668538, ECO:0000269\|PubMed:22267487, ECO:0000269\|PubMed:24689742, ECO:0000269\|PubMed:25655823, ECO:0000269\|PubMed:25757472, ECO:0000269\|PubMed:26303297, ECO:0000269\|PubMed:26574599}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00224	DAP	Transfer from AT1G69690	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Tp5g24820

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian-regulation with the lowest expression in the middle of the dark period (PubMed:21183706). Induced during seed imbibition (PubMed:25655823). Induced by cytokinin (PubMed:26303297). {ECO:0000269\|PubMed:21183706, ECO:0000269\|PubMed:25655823, ECO:0000269\|PubMed:26303297}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	-	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK353330	0.0	AK353330.1 Thellungiella halophila mRNA, complete cds, clone: RTFL01-24-O23.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018442427.1	0.0	PREDICTED: transcription factor TCP15-like
Swissprot	Q9C9L2	1e-156	TCP15_ARATH; Transcription factor TCP15
TrEMBL	A0A3N6RY01	0.0	A0A3N6RY01_BRACR; Uncharacterized protein
STRING	Bo6g110290.1	1e-179	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM12965	18	30

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G69690.1	1e-131	TCP family protein

Publications ? help Back to Top
Steiner E, et al. The Putative O-Linked N-Acetylglucosamine Transferase SPINDLY Inhibits Class I TCP Proteolysis to Promote Sensitivity to Cytokinin. Plant Physiol., 2016. 171(2): p. 1485-94 [PMID:27208284] Dong H, et al. Ubiquitylation activates a peptidase that promotes cleavage and destabilization of its activating E3 ligases and diverse growth regulatory proteins to limit cell proliferation in Arabidopsis. Genes Dev., 2017. 31(2): p. 197-208 [PMID:28167503] Zhang N, et al. MOS1 functions closely with TCP transcription factors to modulate immunity and cell cycle in Arabidopsis. Plant J., 2018. 93(1): p. 66-78 [PMID:29086441] Mazur MJ, et al. Arabidopsis TCP Transcription Factors Interact with the SUMO Conjugating Machinery in Nuclear Foci. Front Plant Sci, 2017. 8: p. 2043 [PMID:29250092]