PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Trifolium

Family

CAMTA

Protein Properties

Length: 1066aa MW: 121134 Da PI: 6.332

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Tp57577_TGAC_v2_mRNA6428	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	179.6	3.9e-56	22	138	3	118
CG-1 3 ke.kkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYa 86 +e + rwl++ ei++iL+n++++++++e+ p+sgsl+L++rk++ryfrkDG++w+kkkdgktvrE+he+LKvg+v+vl+cyYa Tp57577_TGAC_v2_mRNA6428 22 SEaQYRWLRPPEICQILTNHNNFQIASEPSYMPTSGSLFLFDRKVTRYFRKDGHNWRKKKDGKTVREAHERLKVGSVDVLHCYYA 106 44499****************************************************************************** PP CG-1 87 hseenptfqrrcywlLeeelekivlvhylevk 118 h+e+n tfqrr+yw+Lee+l++ivlvhy+evk Tp57577_TGAC_v2_mRNA6428 107 HGEQNDTFQRRTYWMLEEDLSHIVLVHYREVK 138 ***************************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	79.721	17	143	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	5.6E-80	20	138	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	1.8E-49	23	136	IPR005559	CG-1 DNA-binding domain
SuperFamily	SSF81296	6.07E-16	482	567	IPR014756	Immunoglobulin E-set
Pfam	PF01833	1.4E-4	482	558	IPR002909	IPT domain
PROSITE profile	PS50297	17.449	655	779	IPR020683	Ankyrin repeat-containing domain
SuperFamily	SSF48403	3.42E-17	664	779	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	3.07E-13	674	777	No hit	No description
Gene3D	G3DSA:1.25.40.20	2.7E-17	674	783	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	2.8E-7	690	780	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50088	8.763	718	750	IPR002110	Ankyrin repeat
SMART	SM00248	0.076	718	747	IPR002110	Ankyrin repeat
SMART	SM00248	420	757	786	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	2.07E-7	885	941	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	22	891	913	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	6.852	893	921	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.14	894	912	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.0089	914	936	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.157	915	939	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	2.0E-4	917	935	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009409	Biological Process	response to cold
GO:0010150	Biological Process	leaf senescence
GO:0042742	Biological Process	defense response to bacterium
GO:0050832	Biological Process	defense response to fungus
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005516	Molecular Function	calmodulin binding

Sequence ? help Back to Top
Protein Sequence Length: 1066 aa Download sequence Send to blast
MAHNNMRHLH HPNQFDIQQI LSEAQYRWLR PPEICQILTN HNNFQIASEP SYMPTSGSLF 60 LFDRKVTRYF RKDGHNWRKK KDGKTVREAH ERLKVGSVDV LHCYYAHGEQ NDTFQRRTYW 120 MLEEDLSHIV LVHYREVKGA KATLICTKEN EESHPHAQQT YKVMSNTEME TSLPSSTNTA 180 QSSEYDETES AFNSHANSDF YSFLELQHPV VQKIKAQIAD SNCPLPLKDD QQRLPVIPKV 240 DYISLSQPNE TKCINNIGLT CELSKILGFS SCQDILENHS GSHNVPFQPS FPETQSNNMG 300 INGTSQGYEP SGFISLSTST WPNDSAYSVS TCEVSYSDNE KEVNEVDFQQ TLEQFLIHPH 360 QQHKVLMWNS PHEKLLEAEE LKSDLEVGRS LDEIQATHFT SKKTLLDVSL ADEGLKKLDS 420 FNRWMSNELG DVEESSKKST SSAYWDTVES ENGVDSRTIP SLVHLENYVL DPSICYDQLF 480 SIIDYSPCWT FEDSEIKVLI SGRFLKGQNE AEDCKWSCMF GEVEVPAEII GNGVLCCHTP 540 PHKAGRVPFY VTCSNRLACS EVREFDFRAN YTQEVNTGGE SSSSNTFDTF NRRFGELLSL 600 EHDFPHSLDS VSVNEKSQLR SKISSLFRRE DDEWDKLLKF TLEKEFPLEL VQEQLHENLL 660 KDKLHAWLLQ KTTEDGKGPN VLYEYGQGVL HLAAALGYDW ALEPTIVAGV NVNFRDVNGW 720 TALHWAAFCG RERTVVSLIA LGAAPGALTD PCPQHPSGRT PADLASANGH KGIAGYLAES 780 FLSAQLESID LKRGAAESFG TKVVQRVQEQ NTARLNNEGI SHELSLKDSL AAVCNATQAA 840 ARIHQVFRVQ SFQRKQQKEY GDDKFGISDE RALSLIALNA KSHKSGQRDE PVHVAATRIQ 900 NKFRSWKGRK DFLIIRQRIV KIQAHVRGHQ VRKNYGKMKI IWSVGIVEKV ILRWRRKGSG 960 LRGFKSEAVA EGVSSSTEDD YDFLKEGRKQ TEKRLEKALA RVKSMAQYPD ARDQYHRLLN 1020 VVTEIRENQV KQDWSFCNSE ETRQFRSLID LEALLDEDTF MHTAI*

Sequence ? help Back to Top

Protein Sequence Length: 1066 aa Download sequence Send to blast

MAHNNMRHLH HPNQFDIQQI LSEAQYRWLR PPEICQILTN HNNFQIASEP SYMPTSGSLF  60
LFDRKVTRYF RKDGHNWRKK KDGKTVREAH ERLKVGSVDV LHCYYAHGEQ NDTFQRRTYW  120
MLEEDLSHIV LVHYREVKGA KATLICTKEN EESHPHAQQT YKVMSNTEME TSLPSSTNTA  180
QSSEYDETES AFNSHANSDF YSFLELQHPV VQKIKAQIAD SNCPLPLKDD QQRLPVIPKV  240
DYISLSQPNE TKCINNIGLT CELSKILGFS SCQDILENHS GSHNVPFQPS FPETQSNNMG  300
INGTSQGYEP SGFISLSTST WPNDSAYSVS TCEVSYSDNE KEVNEVDFQQ TLEQFLIHPH  360
QQHKVLMWNS PHEKLLEAEE LKSDLEVGRS LDEIQATHFT SKKTLLDVSL ADEGLKKLDS  420
FNRWMSNELG DVEESSKKST SSAYWDTVES ENGVDSRTIP SLVHLENYVL DPSICYDQLF  480
SIIDYSPCWT FEDSEIKVLI SGRFLKGQNE AEDCKWSCMF GEVEVPAEII GNGVLCCHTP  540
PHKAGRVPFY VTCSNRLACS EVREFDFRAN YTQEVNTGGE SSSSNTFDTF NRRFGELLSL  600
EHDFPHSLDS VSVNEKSQLR SKISSLFRRE DDEWDKLLKF TLEKEFPLEL VQEQLHENLL  660
KDKLHAWLLQ KTTEDGKGPN VLYEYGQGVL HLAAALGYDW ALEPTIVAGV NVNFRDVNGW  720
TALHWAAFCG RERTVVSLIA LGAAPGALTD PCPQHPSGRT PADLASANGH KGIAGYLAES  780
FLSAQLESID LKRGAAESFG TKVVQRVQEQ NTARLNNEGI SHELSLKDSL AAVCNATQAA  840
ARIHQVFRVQ SFQRKQQKEY GDDKFGISDE RALSLIALNA KSHKSGQRDE PVHVAATRIQ  900
NKFRSWKGRK DFLIIRQRIV KIQAHVRGHQ VRKNYGKMKI IWSVGIVEKV ILRWRRKGSG  960
LRGFKSEAVA EGVSSSTEDD YDFLKEGRKQ TEKRLEKALA RVKSMAQYPD ARDQYHRLLN  1020
VVTEIRENQV KQDWSFCNSE ETRQFRSLID LEALLDEDTF MHTAI*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00042	PBM	Transfer from AT2G22300	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Tp57577_TGAC_v2_mRNA6428

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013446801.1	0.0	calmodulin-binding transcription activator 1 isoform X2
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A2K3NQX9	0.0	A0A2K3NQX9_TRIPR; Calmodulin-binding transcription activator 3-like protein
STRING	XP_004504077.1	0.0	(Cicer arietinum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8284	27	35

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Link Out ? help Back to Top
Phytozome	Tp57577_TGAC_v2_mRNA6428

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]