PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Trifolium

Family

C2H2

Protein Properties

Length: 470aa MW: 51945.3 Da PI: 8.1706

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Tp57577_TGAC_v2_mRNA33816	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	12.5	0.00045	114	136	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 y+Cp+C+++F++ ++ H ++ Tp57577_TGAC_v2_mRNA33816 114 YECPICKTPFRSEDEVSEHVESC 136 99**************9998776 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF143503	2.09E-18	173	257	IPR018997	PUB domain
CDD	cd09212	7.71E-20	177	261	No hit	No description
SMART	SM00580	2.4E-18	179	246	IPR018997	PUB domain
Pfam	PF09409	3.0E-17	181	253	IPR018997	PUB domain
SuperFamily	SSF54236	9.3E-12	329	442	IPR029071	Ubiquitin-related domain
Gene3D	G3DSA:3.10.20.90	7.6E-8	357	442	No hit	No description
PROSITE profile	PS50033	9.788	358	442	IPR001012	UBX domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0050832	Biological Process	defense response to fungus
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 470 aa Download sequence Send to blast
MDDVKDKFKG FMKKVTSSSS SSSGKFKGQG RVLGSSSSSS SSTPVNSIPT PRPSPSPSQN 60 PNPKPNPNPK PTSTIASNPT RIDKPRKTGD GFDPFDALVT SSQRSKNGYS LNVYECPICK 120 TPFRSEDEVS EHVESCLSNS NERGDNDEKF VSKSEAIVES DTELEICIGT YVSGNPSVGS 180 VDIVLKLLRN IVKEPENVKF RKIRLSNPKI KEAVADVNGG IELLSILGFE LREENGETWA 240 VMEVPTEEKI KLIKKAIVLL EPQLVQDPPK RDNLVSTASA EKVVEAEPAE PKKIDRQVKV 300 FFAVAESVAA KIELPDSFYK RSAEEVRREA ELRKKKFEES QLLIPKSLRE KQAKAAKKRY 360 TRTIIRIQFP DAAVLQGVFA PWEPTSALYE FVSSSIKEPN LEFELMHPVV VQRRVIPCFP 420 KAGQKAKTIE EEDLVPSALI KFKPLETDSV VFTGLKNELL EISEPLVNG*

Sequence ? help Back to Top

Protein Sequence Length: 470 aa Download sequence Send to blast

MDDVKDKFKG FMKKVTSSSS SSSGKFKGQG RVLGSSSSSS SSTPVNSIPT PRPSPSPSQN  60
PNPKPNPNPK PTSTIASNPT RIDKPRKTGD GFDPFDALVT SSQRSKNGYS LNVYECPICK  120
TPFRSEDEVS EHVESCLSNS NERGDNDEKF VSKSEAIVES DTELEICIGT YVSGNPSVGS  180
VDIVLKLLRN IVKEPENVKF RKIRLSNPKI KEAVADVNGG IELLSILGFE LREENGETWA  240
VMEVPTEEKI KLIKKAIVLL EPQLVQDPPK RDNLVSTASA EKVVEAEPAE PKKIDRQVKV  300
FFAVAESVAA KIELPDSFYK RSAEEVRREA ELRKKKFEES QLLIPKSLRE KQAKAAKKRY  360
TRTIIRIQFP DAAVLQGVFA PWEPTSALYE FVSSSIKEPN LEFELMHPVV VQRRVIPCFP  420
KAGQKAKTIE EEDLVPSALI KFKPLETDSV VFTGLKNELL EISEPLVNG*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5ifw_A	1e-13	313	442	23	146	Tether containing UBX domain for GLUT4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Facilitates the interaction of SYP31 and CDC48A, thereby regulating an CDC48A membrane-associated function (Ref.8). Appears to act as a negative regulator mediating the powdery mildew-plant interaction (PubMed:19176722, PubMed:23301616). {ECO:0000269\|PubMed:19176722, ECO:0000269\|PubMed:23301616, ECO:0000269\|Ref.8}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Tp57577_TGAC_v2_mRNA33816

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in response to powdery mildew and by benzothiadiazole (BTH) treatment. {ECO:0000269\|PubMed:19176722}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003630914.1	0.0	plant UBX domain-containing protein 2
Swissprot	Q9ZU93	0.0	PUX2_ARATH; Plant UBX domain-containing protein 2
TrEMBL	A0A2K3P8Y4	0.0	A0A2K3P8Y4_TRIPR; UBX domain-containing protein 6-like
STRING	AET05390	0.0	(Medicago truncatula)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8944	25	29

Link Out ? help Back to Top
Phytozome	Tp57577_TGAC_v2_mRNA33816

Publications ? help Back to Top
Suzuki T,Park H,Till EA,Lennarz WJ The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway. Biochem. Biophys. Res. Commun., 2001. 287(5): p. 1083-7 [PMID:11587532] Rancour DM,Park S,Knight SD,Bednarek SY Plant UBX domain-containing protein 1, PUX1, regulates the oligomeric structure and activity of arabidopsis CDC48. J. Biol. Chem., 2004. 279(52): p. 54264-74 [PMID:15498773] Chandran D,Rickert J,Cherk C,Dotson BR,Wildermuth MC Host cell ploidy underlying the fungal feeding site is a determinant of powdery mildew growth and reproduction. Mol. Plant Microbe Interact., 2013. 26(5): p. 537-45 [PMID:23301616]