PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassicaceae incertae sedis; Schrenkiella

Family

bHLH

Protein Properties

Length: 323aa MW: 36356.8 Da PI: 4.7474

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Tp2g27400	genome	thellungiella	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	18.5	3.7e-06	269	310	8	54
HHHHHHHHHHHHHHHHHCTSCCC...TTS-.STCHHHHHHHHHHHHHH CS HLH 8 rErrRRdriNsafeeLrellPkaskapskK.lsKaeiLekAveYIksL 54 +E+ RRdri++a+ L +++P a K ++ L +A++Y+k L Tp2g27400 269 NEQSRRDRIRTALKILESVVPGA------KgNEALLLLDEAIDYLKLL 310 69******************9......5599999*******987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	10.36	261	310	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	4.97E-7	269	313	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	7.93E-4	270	314	No hit	No description
Gene3D	G3DSA:4.10.280.10	2.7E-5	270	312	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009826	Biological Process	unidimensional cell growth
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 323 aa Download sequence Send to blast
MPLDTRQRDL PPQACFEDIA ARSVRPGIPL PELGKLYAAE LQARCLQPPP FHSLLWSHDK 60 ESCGKRFSQS DIRSWCAAAT TPHGALESSQ KRLMIFDQSG NQTRLLRCPF PLRFPSPAAV 120 EPVKFSELQH GLEKDFREDR VTVKEFDENY IKGKESEMHE DTEEINALLY SDDDYDDDDD 180 YCGSDDEVMS TGHSPYPIEQ VCNKRELEEI DGPCKRQKLL GNVENISGSS SLVGTKSSTK 240 LNESSFLKDE KLPESNISTK EDIGSGLSNE QSRRDRIRTA LKILESVVPG AKGNEALLLL 300 DEAIDYLKLL KRDLISVEIK NHC

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Involved in stem elongation, probably by regulating a subset of genes involved in this process. {ECO:0000269\|PubMed:16936072}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Tp2g27400

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024007486.1	1e-168	transcription factor SAC51
Swissprot	Q9FMF4	1e-159	SAC51_ARATH; Transcription factor SAC51
TrEMBL	V4KNE0	1e-167	V4KNE0_EUTSA; Uncharacterized protein
STRING	Bostr.0568s0367.1.p	1e-170	(Boechera stricta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5546	10	14

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G00050.1	8e-06	bHLH family protein

Publications ? help Back to Top
Imai A, et al. The dwarf phenotype of the Arabidopsis acl5 mutant is suppressed by a mutation in an upstream ORF of a bHLH gene. Development, 2006. 133(18): p. 3575-85 [PMID:16936072] Imai A,Komura M,Kawano E,Kuwashiro Y,Takahashi T A semi-dominant mutation in the ribosomal protein L10 gene suppresses the dwarf phenotype of the acl5 mutant in Arabidopsis thaliana. Plant J., 2008. 56(6): p. 881-90 [PMID:18694459] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Cai Q, et al. The SAC51 Family Plays a Central Role in Thermospermine Responses in Arabidopsis. Plant Cell Physiol., 2016. 57(8): p. 1583-92 [PMID:27388339] Yamamoto M,Takahashi T Thermospermine enhances translation of SAC51 and SACL1 in Arabidopsis. Plant Signal Behav, 2017. 12(1): p. e1276685 [PMID:28045577]