PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassicaceae incertae sedis; Schrenkiella

Family

C2H2

Protein Properties

Length: 257aa MW: 28541.3 Da PI: 6.9067

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Tp2g22370	genome	thellungiella	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14.9	7.9e-05	79	101	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C ++F ++ L H++ H Tp2g22370 79 FSCNYCQRTFYSSQALGGHQNAH 101 89******************988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	6.3E-4	72	105	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	2.99E-7	74	106	No hit	No description
PROSITE profile	PS50157	11.635	79	106	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	81	101	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 257 aa Download sequence Send to blast
MDASDPSCVA SSSSTAFPCQ DSLNQSLKQS FKDEEADVND NYSQEQINQE LNLIDGIDTS 60 IDVSQSYNGS STSTEQKLFS CNYCQRTFYS SQALGGHQNA HKRERTLAKR GQRMAASASA 120 FGHPYGFSPV PFHGQYNNRS LGIQTHSMSH KLISSYNGFG GHYGQINWSR LPLDQQPAIG 180 KLSSMENFHH QPQQQQHHQM MMMDPSVNSR SNNMGRSSSN IGRILVGSPT LEQWRGDGGL 240 LSTNQEDQQK LDLSLKL

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as negative regulator of abscisic acid (ABA) signaling during germination and early seedling development. Involved in the regulation of vegetative development and fertility. Modulates red light signaling in seedling photomorphogenesis. {ECO:0000269\|PubMed:24808098}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Tp2g22370

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by abscisic acid (ABA). {ECO:0000269\|PubMed:24808098}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC005964	1e-121	AC005964.1 Arabidopsis thaliana chromosome V map 60.5 cM, complete sequence.
GenBank	AC006259	1e-121	AC006259.1 Arabidopsis thaliana BAC F21J6 from chromosome V, containing KNAT3 and mapping near 60.5 cM, complete sequence.
GenBank	AK227706	1e-121	AK227706.1 Arabidopsis thaliana mRNA for ZFP3 zinc finger protein, complete cds, clone: RAFL14-29-I08.
GenBank	ATHZFPC	1e-121	L39646.1 Arabidopsis thaliana zinc finger protein (ZFP3) mRNA, complete cds.
GenBank	BT008308	1e-121	BT008308.1 Arabidopsis thaliana At5g25160 gene, complete cds.
GenBank	CP002688	1e-121	CP002688.1 Arabidopsis thaliana chromosome 5 sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006394765.1	1e-144	zinc finger protein 3
Swissprot	Q39262	1e-113	ZFP3_ARATH; Zinc finger protein 3
TrEMBL	V4MKX8	1e-143	V4MKX8_EUTSA; Uncharacterized protein
STRING	XP_006394765.1	1e-143	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1893	27	71

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G25160.1	1e-103	zinc finger protein 3

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Joseph MP, et al. The Arabidopsis ZINC FINGER PROTEIN3 Interferes with Abscisic Acid and Light Signaling in Seed Germination and Plant Development. Plant Physiol., 2014. 165(3): p. 1203-1220 [PMID:24808098] Zhang A, et al. The Arabidopsis Gene zinc finger protein 3(ZFP3) Is Involved in Salt Stress and Osmotic Stress Response. PLoS ONE, 2016. 11(12): p. e0168367 [PMID:27977750]