PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassicaceae incertae sedis; Schrenkiella

Family

HSF

Protein Properties

Length: 286aa MW: 33960.9 Da PI: 7.2747

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Tp2g08640	genome	thellungiella	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	114.1	8.8e-36	20	111	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 F++k+y+i+ed+++++++sws+++nsf+v+++e+fa +Lp yFkh+n++SFvRQLn+YgFkk+++e+ weF++k+F +g+++ll++i+ Tp2g08640 20 FITKTYDIVEDSSTNNIVSWSRDNNSFIVWEPETFAIICLPIYFKHNNLSSFVRQLNTYGFKKIDTER---------WEFANKYFLRGQRHLLKNIR 107 9**************************************************************999.........****************** PP XXXX CS HSF_DNA-bind 99 rkks 102 r+k+ Tp2g08640 108 RRKT 111 *986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46785	8.84E-35	15	109	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	6.2E-52	16	109	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Gene3D	G3DSA:1.10.10.10	6.8E-36	16	109	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00447	1.5E-30	20	109	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.2E-17	20	43	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.2E-17	58	70	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	59	83	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.2E-17	71	83	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 286 aa Download sequence Send to blast
MDYNLPRSLE GLKGTGPTPF ITKTYDIVED SSTNNIVSWS RDNNSFIVWE PETFAIICLP 60 IYFKHNNLSS FVRQLNTYGF KKIDTERWEF ANKYFLRGQR HLLKNIRRRK TPYQTQSLEN 120 GRFGLEREIQ VMRRDKAALV TELVRLRRKQ ENVKAYLRLM EEKVKITEMK QEVMMDFLLN 180 KIKKPDFLQS LRKRKQHGIE NLEQRHEMIL GHGVKDHATF VKAEPEEYSD DIGDQFGGVF 240 GYRDELHIAS MEEQRQDRVE MEMDSEEIWK AFVLSDEMCI LGEHLL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	1e-22	11	111	17	131	Heat shock factor protein 1
5d5v_B	1e-22	11	111	17	131	Heat shock factor protein 1
5d5v_D	1e-22	11	111	17	131	Heat shock factor protein 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00541	DAP	Transfer from AT5G43840	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Tp2g08640

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006403174.1	1e-163	heat stress transcription factor A-6a
Swissprot	Q1PDN3	1e-148	HFA6A_ARATH; Heat stress transcription factor A-6a
TrEMBL	V4LQ79	1e-162	V4LQ79_EUTSA; Uncharacterized protein
STRING	XP_006403174.1	1e-163	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM15683	14	16

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G43840.1	1e-150	heat shock transcription factor A6A

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Song L, et al. A transcription factor hierarchy defines an environmental stress response network. Science, 2017. [PMID:27811239]