PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassicaceae incertae sedis; Schrenkiella

Family

MYB

Protein Properties

Length: 315aa MW: 35847.1 Da PI: 6.9292

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Tp2g05930	genome	thellungiella	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	54.8	2.2e-17	14	61	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g W++eEde+l++++++ G g+W+++++ g+ R++k+c++rw +yl Tp2g05930 14 KGLWSPEEDERLLNYITRNGHGCWSSVPKLAGLERCGKSCRLRWINYL 61 678*******************************************97 PP
2	Myb_DNA-binding	45	2.5e-14	67	110	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 rg +++eE+ l+v+++ lG++ W+ Ia++++ gRt++++k+ w++ Tp2g05930 67 RGDFSPEEQNLIVELHSVLGNR-WSQIAARFP-GRTDNEIKNLWNS 110 899*****************.*****.*******9986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	1.6E-24	7	64	IPR009057	Homeodomain-like
PROSITE profile	PS51294	17.983	9	61	IPR017930	Myb domain
SuperFamily	SSF46689	5.99E-29	12	108	IPR009057	Homeodomain-like
SMART	SM00717	6.9E-12	13	63	IPR001005	SANT/Myb domain
Pfam	PF00249	5.0E-15	14	61	IPR001005	SANT/Myb domain
CDD	cd00167	5.85E-10	17	61	No hit	No description
PROSITE profile	PS51294	24.639	62	116	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	8.1E-25	65	116	IPR009057	Homeodomain-like
SMART	SM00717	2.6E-12	66	114	IPR001005	SANT/Myb domain
Pfam	PF00249	4.3E-13	67	110	IPR001005	SANT/Myb domain
CDD	cd00167	4.63E-9	70	109	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009733	Biological Process	response to auxin
GO:0009739	Biological Process	response to gibberellin
GO:0009751	Biological Process	response to salicylic acid
GO:0009753	Biological Process	response to jasmonic acid
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 315 aa Download sequence Send to blast
MGRHSSSYKQ KLRKGLWSPE EDERLLNYIT RNGHGCWSSV PKLAGLERCG KSCRLRWINY 60 LRPDLKRGDF SPEEQNLIVE LHSVLGNRWS QIAARFPGRT DNEIKNLWNS CIKKKLRQKG 120 IDPNTHKPLS EVDKDHKSPS FSSETNQDFG FSGYLALQKL NSSSSPEHYV SIDNPLCSMI 180 PTQFNVDGSV SNAVFETQIY VKPSVILLSP PDNVCTVPGG DHVKETESNW RSNCGTITNN 240 TSSYLDYPGL DEMKWSDEYL NALLFTSQNQ ISNPIYVKSE RDFNYNTDFP WSQSQDADVH 300 LKDLQIMAVS FGQNL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1a5j_A	3e-27	12	116	5	108	B-MYB
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that coordinates a small network of downstream target genes required for several aspects of plant growth and development, such as xylem formation and xylem cell differentiation, and lateral root formation (PubMed:22708996). Regulates a specific set of target genes by binding DNA to the AC cis-element 5'-ACCTAC-3' (PubMed:23741471). Functions as a transcriptional regulator of stomatal closure. Plays a role the regulation of stomatal pore size independently of abscisic acid (ABA) (PubMed:16005292). Required for seed coat mucilage deposition during the development of the seed coat epidermis (PubMed:19401413). Involved in the induction of trichome initiation and branching by positively regulating GL1 and GL2. Required for gibberellin (GA) biosynthesis and degradation by positively affecting the expression of the enzymes that convert GA9 into the bioactive GA4, as well as the enzymes involved in the degradation of GA4 (PubMed:28207974). {ECO:0000269\|PubMed:16005292, ECO:0000269\|PubMed:19401413, ECO:0000269\|PubMed:22708996, ECO:0000269\|PubMed:23741471, ECO:0000269\|PubMed:28207974}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Tp2g05930

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY550304	1e-123	AY550304.1 Arabidopsis thaliana MYB transcription factor (At1g57557) mRNA, complete cds.
GenBank	BT029225	1e-123	BT029225.1 Arabidopsis thaliana At1g57560 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006392397.1	1e-163	transcription factor MYB61
Swissprot	Q8VZQ2	1e-123	MYB61_ARATH; Transcription factor MYB61
TrEMBL	A0A1J3JX34	1e-171	A0A1J3JX34_NOCCA; Transcription factor MYB86
STRING	XP_006392397.1	1e-162	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4	28	2646

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G57560.1	1e-152	myb domain protein 50

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Matías-Hernández L, et al. AaMYB1 and its orthologue AtMYB61 affect terpene metabolism and trichome development in Artemisia annua and Arabidopsis thaliana. Plant J., 2017. 90(3): p. 520-534 [PMID:28207974]