PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassicaceae incertae sedis; Schrenkiella

Family

ERF

Protein Properties

Length: 274aa MW: 31009.7 Da PI: 7.6337

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Tp2g00490	genome	thellungiella	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	58.3	2e-18	101	150	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 +++GVr+++ +g+W+AeIrdp +r r +lg+f taeeAak +++a+ +l+g Tp2g00490 101 KFRGVRQRP-WGKWAAEIRDP----IRrVRRWLGTFNTAEEAAKVYDHAAVQLHG 150 79*****.******7....246999******************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PIRSF	PIRSF038123	3.1E-52	5	270	IPR017392	AP2/ERF transcription factor ERF/PTI6
PROSITE pattern	PS00315	0	43	60	IPR030513	Dehydrin, conserved site
SMART	SM00380	3.0E-33	101	164	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	3.79E-21	101	159	IPR016177	DNA-binding domain
PROSITE profile	PS51032	23.327	101	158	IPR001471	AP2/ERF domain
CDD	cd00018	2.12E-30	101	160	No hit	No description
Pfam	PF00847	2.3E-10	101	150	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	4.2E-28	101	158	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.1E-9	102	113	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.1E-9	124	140	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 274 aa Download sequence Send to blast
MEKGLISQRE HRRTIKHTYS LKRSVDTPRI LRISVTDPYA TDSSSSDDDD EDNGTRKRRR 60 VKRYVREITF ETPSFTTEHQ NDTVSKKRVL SESTEKKKKL KFRGVRQRPW GKWAAEIRDP 120 IRRVRRWLGT FNTAEEAAKV YDHAAVQLHG LAAVTNFPAA LIPPEPPCTA ACIQSPVTVL 180 LSPTSSDSLS NSPAGGEDRF AAAAQKTIFP PIDSVFLSDD FKLSEISVED CFSVGFSSTF 240 GFSNRHVEDR FYDIGDLFGS DHFLDFDYFF GSDL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	2e-18	101	158	14	72	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	55	59	RKRRR
2	55	62	RKRRRVKR
3	56	60	KRRRV

Functional Description ? help Back to Top
Source	Description
UniProt	Component of the cytokinin signaling pathway involved in cotyledons, leaves, and embryos development. Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269\|PubMed:16832061}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Tp2g00490

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006391650.2	1e-134	ethylene-responsive transcription factor CRF1
Swissprot	O82503	2e-51	CRF1_ARATH; Ethylene-responsive transcription factor CRF1
TrEMBL	V4MCI3	1e-120	V4MCI3_EUTSA; Uncharacterized protein (Fragment)
STRING	XP_006391650.1	1e-121	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM22624	4	4

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G11140.1	6e-32	cytokinin response factor 1

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Raines T, et al. The cytokinin response factors modulate root and shoot growth and promote leaf senescence in Arabidopsis. Plant J., 2016. 85(1): p. 134-47 [PMID:26662515]