PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassicaceae incertae sedis; Schrenkiella

Family

ERF

Protein Properties

Length: 248aa MW: 27337.4 Da PI: 9.2631

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Tp1g37460	genome	thellungiella	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	66.1	6.8e-21	36	86	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.psengkrkrfslgkfgtaeeAakaaiaarkkleg 55 ++++GVr ++ +gr++AeIrd ++ + r++lg+f++aeeAa+a++aa+++l+g Tp1g37460 36 TRFRGVRKRP-WGRFAAEIRDpWK----KSRVWLGTFDSAEEAARAYDAAARNLRG 86 589*****.******883....5***********************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	1.30E-17	36	96	No hit	No description
Pfam	PF00847	1.1E-13	36	86	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	2.68E-22	37	96	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	2.2E-31	37	94	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	23.485	37	94	IPR001471	AP2/ERF domain
SMART	SM00380	3.0E-36	37	100	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.3E-10	38	49	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.3E-10	60	76	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 248 aa Download sequence Send to blast
MRRGRGSSAV AVAGPTAAPV PGGAIIANHN GSLKETRFRG VRKRPWGRFA AEIRDPWKKS 60 RVWLGTFDSA EEAARAYDAA ARNLRGPKAK TNFPIDCFPS SPQQQQNLRF SSQNQNQVDP 120 FMDHRLYSGV SPHLTEQQYP IVSRPTSSSM SSTVESFSGP RPTATSSVAK PPSMTKTKRY 180 PRTPPLVPED CHSDCDSSSS VIDDGDDDIA SSSRRRNPPF QFDLNFPPLD AVDFFNGIDD 240 LHCTDLRL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	9e-20	37	94	14	72	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as a transcriptional repressor. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways and could also regulate other AtERFs. {ECO:0000269\|PubMed:10715325, ECO:0000269\|PubMed:11487705, ECO:0000269\|PubMed:9756931}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00194	DAP	Transfer from AT1G50640	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Tp1g37460

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by jasmonate (JA), ethylene and Alternaria brassicicola (locally and systemically). Moderate induction by wounding or drought stress does not require EIN2, whereas induction by NaCl does. Transcripts accumulate slightly in cycloheximide-treated plants, a protein synthesis inhibitor. Seems to not be influenced by ethylene, exogenous abscisic acid (ABA), cold and heat stress. {ECO:0000269\|PubMed:10715325, ECO:0000269\|PubMed:12805630}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	-	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY085023	4e-57	AY085023.1 Arabidopsis thaliana clone 124720 mRNA, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024006312.1	1e-131	ethylene-responsive transcription factor 3
Swissprot	O80339	1e-92	ERF82_ARATH; Ethylene-responsive transcription factor 3
TrEMBL	V4KSQ7	1e-129	V4KSQ7_EUTSA; Uncharacterized protein
STRING	XP_006393127.1	1e-130	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10	28	1650

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G50640.1	1e-68	ethylene responsive element binding factor 3

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]