PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema

Family

bHLH

Protein Properties

Length: 291aa MW: 33095.6 Da PI: 8.4451

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thhalv10025899m	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26.8	9.5e-09	152	198	5	55
HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-.STCHHHHHHHHHHHHHHH CS HLH 5 hnerErrRRdriNsafeeLrellPkaskapskK.lsKaeiLekAveYIksLq 55 h+ +Er RR++i +++ L++++P + +K Ka +L + ++Y++sLq Thhalv10025899m 152 HSLAERARREKISKKMKCLQDIVPGC-----TKvTGKAGMLDEIINYVQSLQ 198 999********************9.....78899*************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	2.62E-16	145	217	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.49E-7	145	202	No hit	No description
PROSITE profile	PS50888	14.405	147	197	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	6.1E-17	149	216	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.0E-6	152	198	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.3E-9	153	203	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006351	Biological Process	transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 291 aa Download sequence Send to blast
MDLYIPEKLK WLQQQQMVSP EFLQILGSGG REELKRVESY LGNTNDELQS FRHFPEFGPD 60 YNVIDGCISR TSSFQMEPVK NDEVNRAISF QNKRKPEGKT EKREKKKIKT EAETETSMKG 120 KSNMSNTETS SEIQKPDYIH VRARRGEATD RHSLAERARR EKISKKMKCL QDIVPGCTKV 180 TGKAGMLDEI INYVQSLQQQ VEFLSMKLSV LNPELEFHIN ELSTKQFQAY FADLPEAVSK 240 QSVMADLQSF PLHQQGSLDY SVINSSQTTS LGIIRHLQAG KLTHNLFTTA *

Functional Description ? help Back to Top
Source	Description
UniProt	Positive regulator of brassinosteroid signaling. {ECO:0000269\|PubMed:12454087}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Thhalv10025899m

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by flagellin, jasmonic acid (JA), brassinosteroid and cytokinin, and repressed by abscisic acid. Insensitive to gibberellic acid. {ECO:0000269\|PubMed:12454087, ECO:0000269\|PubMed:12679534}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK352723	0.0	AK352723.1 Thellungiella halophila mRNA, complete cds, clone: RTFL01-02-A24.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006411992.1	0.0	transcription factor BEE 2 isoform X1
Swissprot	Q93VJ4	1e-178	BEE2_ARATH; Transcription factor BEE 2
TrEMBL	V4ML41	0.0	V4ML41_EUTSA; Uncharacterized protein
STRING	XP_006411992.1	0.0	(Eutrema salsugineum)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36540.1	1e-161	BR enhanced expression 2

Link Out ? help Back to Top
Phytozome	Thhalv10025899m
Entrez Gene	18028467

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Singh M,Gupta A,Singh D,Khurana JP,Laxmi A Arabidopsis RSS1 Mediates Cross-Talk Between Glucose and Light Signaling During Hypocotyl Elongation Growth. Sci Rep, 2017. 7(1): p. 16101 [PMID:29170398]