PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema

Family

bHLH

Protein Properties

Length: 313aa MW: 34801.5 Da PI: 4.7881

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thhalv10021177m	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	36.2	1.1e-11	163	210	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rE+rRR+++N++f L ++l + + +K +K++iL A++ +++L Thhalv10021177m 163 SKACREKRRREQLNEKFTDLSSVLEPT---RTPKTDKSAILDDAIRVVNQL 210 5678********************9...9**************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	4.71E-13	152	224	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	3.56E-9	157	211	No hit	No description
PROSITE profile	PS50888	13.141	159	210	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	4.0E-9	163	210	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	7.6E-11	165	216	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.7E-13	166	232	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 313 aa Download sequence Send to blast
MYPSIEDDDD LLASLCFDQS DGAEDPYAFI QTDQENLFPE FGSSGVNLQA EQGQVCNIGA 60 QFDSFSGNFP QVYSSSIGSA QLDLGASYSG VLQQEAHQVC SFRGQNNDSS TRVHQEHEQV 120 CSGVVVEINS SSSIGAIKEE QEHVQEECSR KRGRTGSCSK LGSKACREKR RREQLNEKFT 180 DLSSVLEPTR TPKTDKSAIL DDAIRVVNQL RGEAHELKET NQTLLDEIKS LKAEKNELRE 240 EKLVLKADKE KMEQQLKSMA VPSPSFMHSH PAAFHPSKMA VYPSYGYYPN MQMWPYLHPP 300 ERDTSQDPSP AA*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	149	171	RKRGRTGSCSKLGSKACREKRRR

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00372	DAP	Transfer from AT3G23210	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Thhalv10021177m

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006406065.1	0.0	transcription factor bHLH34
Swissprot	Q9LTC7	1e-152	BH034_ARATH; Transcription factor bHLH34
TrEMBL	V4M5H8	0.0	V4M5H8_EUTSA; Uncharacterized protein
STRING	XP_006406065.1	0.0	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4026	26	53

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23210.1	1e-154	bHLH family protein

Link Out ? help Back to Top
Phytozome	Thhalv10021177m
Entrez Gene	18025066

Publications ? help Back to Top
Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786]