PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema

Family

bHLH

Protein Properties

Length: 220aa MW: 24791.8 Da PI: 6.4217

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thhalv10015330m	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26.7	9.9e-09	136	176	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L Thhalv10015330m 136 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIRYVKFL 176 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.091	127	176	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.1E-11	132	183	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	6.02E-14	133	186	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.2E-12	133	182	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	4.2E-6	137	176	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	9.73E-6	150	181	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010500	Biological Process	transmitting tissue development
GO:0048462	Biological Process	carpel formation
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 220 aa Download sequence Send to blast
MNNNNMNPSL FQNYTWNNII INNNNKNDHH HHNDPIGMAM DQHTHLHMFN PFTSSSSSSS 60 SSSHFPPLSS SLTTTLLSDD QEEDEDEDEP LEELSAMKEM MYKIAAMQPV DIDPATVMKP 120 KRRNVRISDD PQSVAARHRR ERISERIRIL QRLVPGGTKM DTASMLDEAI RYVKFLKRQI 180 RLLNNLPPPP QYQASQAMTS WVSPPPPDFG GGGGGEKLN*

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Thhalv10015330m

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB020752	1e-131	AB020752.1 Arabidopsis thaliana genomic DNA, chromosome 5, P1 clone: MTH16.
GenBank	AL353994	1e-131	AL353994.1 Arabidopsis thaliana DNA chromosome 5, BAC clone F17I14 (ESSA project).
GenBank	CP002688	1e-131	CP002688.1 Arabidopsis thaliana chromosome 5 sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006399458.1	1e-163	transcription factor HEC3
Swissprot	Q9LXD8	2e-78	HEC3_ARATH; Transcription factor HEC3
TrEMBL	V4N5W5	1e-161	V4N5W5_EUTSA; Uncharacterized protein
STRING	XP_006399458.1	1e-162	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4449	27	54

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G09750.1	8e-48	bHLH family protein

Link Out ? help Back to Top
Phytozome	Thhalv10015330m
Entrez Gene	18019490

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231]