PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema

Family

MYB_related

Protein Properties

Length: 269aa MW: 29437.8 Da PI: 10.2732

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thhalv10014394m	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	38.9	2e-12	131	175	3	47
SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 +WT+eE+ ++ + ++lG+g+W+ I+r++ ++++ q+ s+ qky Thhalv10014394m 131 PWTEEEHRTFLIGLEKLGKGDWRGISRKFVVTKSPTQVASHAQKY 175 8*******************************************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50158	8.532	41	56	IPR001878	Zinc finger, CCHC-type
PROSITE profile	PS51294	18.717	123	180	IPR017930	Myb domain
SuperFamily	SSF46689	5.46E-16	126	180	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	1.1E-17	127	179	IPR006447	Myb domain, plants
Gene3D	G3DSA:1.10.10.60	1.6E-9	128	174	IPR009057	Homeodomain-like
SMART	SM00717	9.1E-9	128	178	IPR001005	SANT/Myb domain
Pfam	PF00249	2.7E-10	131	175	IPR001005	SANT/Myb domain
CDD	cd00167	3.57E-8	131	176	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0016021	Cellular Component	integral component of membrane
GO:0003677	Molecular Function	DNA binding
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 269 aa Download sequence Send to blast
MLSTILHKPQ NLSSSSTSSL RLFLPLSLFL LLSFTFITMG RRCSHCGNIG HNSRTCSSYK 60 TRAIRLFGVH LDTTCSSPPP PPPPLSILAT AMKKSFSMDC LPACSSSSSS FCGYLSDGLA 120 HKTPDRKKGV PWTEEEHRTF LIGLEKLGKG DWRGISRKFV VTKSPTQVAS HAQKYFLRQA 180 TTLHHKRRRT SLFDMVSAIN VEENSTIPCN NHIGSTTDVV WKQGLLNPRL GYPDPKISGS 240 GNSGGLDLEL KLASHHSSES NIRPISVT*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription repressor that binds to 5'-TATCCA-3' elements in gene promoters. Contributes to the sugar-repressed transcription of promoters containing SRS or 5'-TATCCA-3' elements. Transcription repressor involved in a cold stress response pathway that confers cold tolerance. Suppresses the DREB1-dependent signaling pathway under prolonged cold stress. DREB1 responds quickly and transiently while MYBS3 responds slowly to cold stress. They may act sequentially and complementarily for adaptation to short- and long-term cold stress (PubMed:20130099). {ECO:0000269\|PubMed:12172034, ECO:0000269\|PubMed:20130099}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00565	DAP	Transfer from AT5G56840	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Thhalv10014394m

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by sucrose and gibberellic acid (GA) (PubMed:12172034). Induced by cold stress in roots and shoots. Induced by salt stress in shoots. Down-regulated by abscisic aci (ABA) in shoots (PubMed:20130099). {ECO:0000269\|PubMed:12172034, ECO:0000269\|PubMed:20130099}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT012528	0.0	BT012528.1 Arabidopsis thaliana At5g56840 gene, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006401279.2	1e-171	transcription factor MYBS3
Swissprot	Q7XC57	5e-46	MYBS3_ORYSJ; Transcription factor MYBS3
TrEMBL	V4LJV3	0.0	V4LJV3_EUTSA; Uncharacterized protein
STRING	XP_006401279.1	0.0	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5496	27	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G56840.1	1e-129	MYB_related family protein

Link Out ? help Back to Top
Phytozome	Thhalv10014394m
Entrez Gene	18017251

Publications ? help Back to Top
Rice Chromosome 10 Sequencing Consortium In-depth view of structure, activity, and evolution of rice chromosome 10. Science, 2003. 300(5625): p. 1566-9 [PMID:12791992] Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764] Su CF, et al. A novel MYBS3-dependent pathway confers cold tolerance in rice. Plant Physiol., 2010. 153(1): p. 145-58 [PMID:20130099]