PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Thhalv10012583m

Common Name

EUTSA_v10012583mg

Organism

Eutrema salsugineum

Taxonomic ID

72664

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema

Family

MYB

Protein Properties

Length: 965aa MW: 108147 Da PI: 4.9483

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thhalv10012583m	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	59.2	9.1e-19	36	82	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg WT+eEde+l++av+ + g++Wk+Ia+++ Rt+ qc +rwqk+l Thhalv10012583m 36 RGQWTAEEDEILKKAVHNFKGKNWKKIAEYFK-DRTDVQCLHRWQKVL 82 89***************************9.**********986 PP
2	Myb_DNA-binding	62.8	7e-20	88	134	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT+eEde +v++++++G++ W+tIar ++ gR +kqc++rw+++l Thhalv10012583m 88 KGPWTKEEDEMIVQLIQKYGPKKWSTIARFLP-GRIGKQCRERWHNHL 134 79****************************.***********97 PP
3	Myb_DNA-binding	43.7	6.3e-14	140	182	1	45
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 + +WT+eE++ l++a++ +G++ W+ ++++ gR+++ +k++w+ Thhalv10012583m 140 KEAWTQEEELVLIRAHQVYGNR-WAELTKYLP-GRSDNGIKNHWH 182 579*****************.*****.*********8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	18.841	31	82	IPR017930	Myb domain
SuperFamily	SSF46689	2.66E-15	33	88	IPR009057	Homeodomain-like
SMART	SM00717	2.2E-15	35	84	IPR001005	SANT/Myb domain
Pfam	PF00249	1.7E-16	36	82	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	5.3E-23	38	90	IPR009057	Homeodomain-like
CDD	cd00167	9.06E-14	39	82	No hit	No description
PROSITE profile	PS51294	32.297	83	138	IPR017930	Myb domain
SuperFamily	SSF46689	1.01E-31	85	181	IPR009057	Homeodomain-like
SMART	SM00717	5.1E-19	87	136	IPR001005	SANT/Myb domain
Pfam	PF00249	1.1E-17	88	134	IPR001005	SANT/Myb domain
CDD	cd00167	1.18E-16	90	134	No hit	No description
Gene3D	G3DSA:1.10.10.60	2.1E-27	91	138	IPR009057	Homeodomain-like
SMART	SM00717	1.8E-12	139	187	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	1.1E-19	139	189	IPR009057	Homeodomain-like
PROSITE profile	PS51294	18.426	139	189	IPR017930	Myb domain
Pfam	PF00249	4.7E-12	140	182	IPR001005	SANT/Myb domain
CDD	cd00167	1.69E-9	142	182	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0032875	Biological Process	regulation of DNA endoreduplication
GO:0003677	Molecular Function	DNA binding
GO:0003713	Molecular Function	transcription coactivator activity

Sequence ? help Back to Top
Protein Sequence Length: 965 aa Download sequence Send to blast
MESECATIST PPEGLIDGSS KTRHGRTSGP ARRSTRGQWT AEEDEILKKA VHNFKGKNWK 60 KIAEYFKDRT DVQCLHRWQK VLNPELVKGP WTKEEDEMIV QLIQKYGPKK WSTIARFLPG 120 RIGKQCRERW HNHLNPAINK EAWTQEEELV LIRAHQVYGN RWAELTKYLP GRSDNGIKNH 180 WHSSVKKKLD SYMSSGLLDQ YQAMPLAPYE RSSTLQSAYM QRSIDGNGCL TGQAEKESEN 240 CQNSSMAGCS LSARDYPNGV TNMEHHFHPC ENSHQNEQAA YQSDQYFYPE LEDISVSISE 300 ISYDMEDCSQ FPDHNVSASS SQDYQFDFQD LSDISLEMRH NMSEVQMPYT KESKESTRGA 360 PNYTSNLDVA TYTNPATVST SETECCRVLF LDQESEGLSV SRSLTQEPNE VDQADYRDPI 420 FCASASDSQI SEATKSPIQS SSSKFTATAA SGKETLRPAP LIISPDKSSG LIFHPFETEP 480 NCRTNENGSF ICIDDPSSST CVDEGPNNSS EEGQSYHLND SKKLVPVNDF ASLAEVKPDS 540 LPKHESNMTS EQHHEDVGAS SSLCFPSLDL PLFNCDISQS KNDLLHDYSP LGIRKLLMST 600 MTCMSPLRLW ESPTGKKTLV GAKSILRKRT RDLLTPLSEK RSDKKLETDI AASLAKDFSR 660 LDVMFDESES RESISGNSTG FNLGDKENNF QILNGEGEEN WRGKPSSLYS HKMPEETMHI 720 RISLDKPEQT CMEANVREKD DSGLYIAESF SGVLSESNTN KPVLSSPDQS VNKAEKAQAS 780 TPRDHLQRTL MATSNKEQHS SASLCLVINS PSRARINTEG HLVDNETSNE NFSIFCGTPF 840 KRGLESPSAW KSPFYINSLL SSPRFDTEIT IEDMGYIFSP GERSFESIGV MTQKNEQTSA 900 FAAFKDAMEV SLSSSDNDAE KKKELDKENN DPLLAERRVL DFNDCESPTK VTEEVSSYLL 960 KECR*

Sequence ? help Back to Top

Protein Sequence Length: 965 aa Download sequence Send to blast

MESECATIST PPEGLIDGSS KTRHGRTSGP ARRSTRGQWT AEEDEILKKA VHNFKGKNWK  60
KIAEYFKDRT DVQCLHRWQK VLNPELVKGP WTKEEDEMIV QLIQKYGPKK WSTIARFLPG  120
RIGKQCRERW HNHLNPAINK EAWTQEEELV LIRAHQVYGN RWAELTKYLP GRSDNGIKNH  180
WHSSVKKKLD SYMSSGLLDQ YQAMPLAPYE RSSTLQSAYM QRSIDGNGCL TGQAEKESEN  240
CQNSSMAGCS LSARDYPNGV TNMEHHFHPC ENSHQNEQAA YQSDQYFYPE LEDISVSISE  300
ISYDMEDCSQ FPDHNVSASS SQDYQFDFQD LSDISLEMRH NMSEVQMPYT KESKESTRGA  360
PNYTSNLDVA TYTNPATVST SETECCRVLF LDQESEGLSV SRSLTQEPNE VDQADYRDPI  420
FCASASDSQI SEATKSPIQS SSSKFTATAA SGKETLRPAP LIISPDKSSG LIFHPFETEP  480
NCRTNENGSF ICIDDPSSST CVDEGPNNSS EEGQSYHLND SKKLVPVNDF ASLAEVKPDS  540
LPKHESNMTS EQHHEDVGAS SSLCFPSLDL PLFNCDISQS KNDLLHDYSP LGIRKLLMST  600
MTCMSPLRLW ESPTGKKTLV GAKSILRKRT RDLLTPLSEK RSDKKLETDI AASLAKDFSR  660
LDVMFDESES RESISGNSTG FNLGDKENNF QILNGEGEEN WRGKPSSLYS HKMPEETMHI  720
RISLDKPEQT CMEANVREKD DSGLYIAESF SGVLSESNTN KPVLSSPDQS VNKAEKAQAS  780
TPRDHLQRTL MATSNKEQHS SASLCLVINS PSRARINTEG HLVDNETSNE NFSIFCGTPF  840
KRGLESPSAW KSPFYINSLL SSPRFDTEIT IEDMGYIFSP GERSFESIGV MTQKNEQTSA  900
FAAFKDAMEV SLSSSDNDAE KKKELDKENN DPLLAERRVL DFNDCESPTK VTEEVSSYLL  960
KECR*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h88_C	8e-69	36	189	6	159	MYB PROTO-ONCOGENE PROTEIN
1h89_C	8e-69	36	189	6	159	MYB PROTO-ONCOGENE PROTEIN
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (PubMed:21862669). Involved in the regulation of cytokinesis, probably via the activation of several G2/M phase-specific genes transcription (e.g. KNOLLE) (PubMed:17287251, PubMed:21862669, PubMed:25806785). Required for the maintenance of diploidy (PubMed:21862669). {ECO:0000269\|PubMed:17287251, ECO:0000269\|PubMed:21862669, ECO:0000269\|PubMed:25806785}.; FUNCTION: Involved in transcription regulation during induced endoreduplication at the powdery mildew (e.g. G.orontii) infection site, thus promoting G.orontii growth and reproduction. {ECO:0000269\|PubMed:20018666}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00505	DAP	Transfer from AT5G11510	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Thhalv10012583m

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Slightly induced by salicylic acid (SA) (PubMed:16463103). Expressed in a cell cycle-dependent manner, with highest levels 2 hours before the peak of mitotic index in cells synchronized by aphidicolin. Activated by CYCB1 (PubMed:17287251). Accumulates at powdery mildew (e.g. G.orontii) infected cells. {ECO:0000269\|PubMed:16463103, ECO:0000269\|PubMed:17287251}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF371975	0.0	AF371975.2 Arabidopsis thaliana putative c-myb-like transcription factor MYB3R-4 (MYB3R4) mRNA, complete cds.
GenBank	AY519650	0.0	AY519650.1 Arabidopsis thaliana MYB transcription factor (At5g11510) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006399657.1	0.0	transcription factor MYB3R-4
Swissprot	Q94FL9	0.0	MB3R4_ARATH; Transcription factor MYB3R-4
TrEMBL	V4KT42	0.0	V4KT42_EUTSA; Uncharacterized protein
STRING	XP_006399657.1	0.0	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM13213	18	28

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G11510.1	0.0	myb domain protein 3r-4

Link Out ? help Back to Top
Phytozome	Thhalv10012583m
Entrez Gene	18017142

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Saito T, et al. Genetic interaction between G2/M phase-specific transcription factor MYB3R4 and MAPKKK ANP3 for execution of cytokinesis in Arabidopsis thaliana. Plant Signal Behav, 2015. 10(3): p. e990817 [PMID:25806785] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325] Chen P, et al. Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage. Nat Commun, 2017. 8(1): p. 635 [PMID:28935922]