PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema

Family

bHLH

Protein Properties

Length: 227aa MW: 25467.9 Da PI: 6.5202

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thhalv10008699m	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	28.8	2.2e-09	115	162	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR++iN+++ L++l+P + k + a +Le ++Y++sLq Thhalv10008699m 115 SHSLAERVRREKINEKLKCLQDLVPGC----YKTMGMAVMLEVIIDYVRSLQ 162 8***********************9....355999***********98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00083	2.31E-12	109	166	No hit	No description
SuperFamily	SSF47459	1.57E-16	109	178	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.1E-16	111	172	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.472	111	161	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.0E-6	115	162	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	8.6E-9	117	167	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:2000488	Biological Process	positive regulation of brassinosteroid biosynthetic process
GO:0005634	Cellular Component	nucleus
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 227 aa Download sequence Send to blast
MARFEPYNYS IGLHPLLAQI NKNPELTNLD SPVSTPSSFM LFSNGALVDA HHNDSHFSPN 60 LLAPGGLGRK GKKEESGSKR RRKRSEEEEF MNEDDIQKPR DVVHVRAKRG QATDSHSLAE 120 RVRREKINEK LKCLQDLVPG CYKTMGMAVM LEVIIDYVRS LQNQIEFLSM KLSVASAYYD 180 LNSLDIEPTD MYQGGNMYGA EEMEKILRES VGTQPPNFSS TLPFGP*

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Thhalv10008699m

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	DQ652859	0.0	DQ652859.1 Arabidopsis thaliana clone 0000017109_0000011994 unknown mRNA.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006415858.1	1e-169	transcription factor bHLH75
Swissprot	A4D998	1e-125	BH075_ARATH; Transcription factor bHLH75
TrEMBL	V4MR53	1e-167	V4MR53_EUTSA; Uncharacterized protein
STRING	XP_006415858.1	1e-168	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM14081	20	24

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G25330.1	1e-118	bHLH family protein

Link Out ? help Back to Top
Phytozome	Thhalv10008699m
Entrez Gene	18992399

Publications ? help Back to Top
Khan M, et al. Interplay between phosphorylation and SUMOylation events determines CESTA protein fate in brassinosteroid signalling. Nat Commun, 2014. 5: p. 4687 [PMID:25134617] Eremina M, et al. Brassinosteroids participate in the control of basal and acquired freezing tolerance of plants. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(40): p. E5982-E5991 [PMID:27655893] Pfannebecker KC,Lange M,Rupp O,Becker A Seed Plant-Specific Gene Lineages Involved in Carpel Development. Mol. Biol. Evol., 2017. 34(4): p. 925-942 [PMID:28087776]