PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Thhalv10007411m

Common Name

EUTSA_v10007411mg

Organism

Eutrema salsugineum

Taxonomic ID

72664

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema

Family

C2H2

Protein Properties

Length: 507aa MW: 56215.7 Da PI: 5.9033

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thhalv10007411m	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	21.1	8.4e-07	255	276	2	23
EETTTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCpdCgksFsrksnLkrHirtH 23 C++Cgk F+r nL+ H+r H Thhalv10007411m 255 FCTICGKGFKRDANLRMHMRGH 276 6*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.32E-5	252	279	No hit	No description
SMART	SM00355	0.0026	254	276	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	12.03	254	281	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	7.2E-6	255	307	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	256	276	IPR007087	Zinc finger, C2H2
SMART	SM00355	33	305	338	IPR015880	Zinc finger, C2H2-like
SMART	SM00355	45	343	365	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010044	Biological Process	response to aluminum ion
GO:0010447	Biological Process	response to acidic pH
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 507 aa Download sequence Send to blast
METEDDMCQN NWGSLSSSSK LEDGNQAFAG FTSQQKWEDA EILDYEMGIE KNLQAFDQMK 60 PSSGQDNDNN NKNNNSTQAN VDFLQGVKAQ AWDPRTMLSN LSFMEQKIHE LQDLVHLIVG 120 RNGLVAQQQQ QLITTDLTSI IIQLISTAGS LLPSVKHNMS STAPGPYTGS AVFPCPREAN 180 NVASQSQNSN HQRGATQDFD LPKPIVVDER DSHVVEEHEM KDEDDAEEGV ENLPPGSYEI 240 LQLEKEEILA PHTHFCTICG KGFKRDANLR MHMRGHGDEY KTPAALAKPN KEAVPGTEPM 300 LIKRYSCPFP GCKRNKDHKK FQALKTILCV KNHYKRTHCD KSFTCSRCHT KKFSVIADLK 360 THEKHCGKNK WLCSCGTTFS RKDKLFGHIA LFQGHTPAIP LEETKPSAQR GSSEGENNNT 420 GMVGFNLGSA TNADQETEQP GFMEEKISFE ESFSPLSFDT CNFGGFHEFP RPMFDDSESS 480 FQMLISSACG FSPRNGGGGS VSNTIL*

Sequence ? help Back to Top

Protein Sequence Length: 507 aa Download sequence Send to blast

METEDDMCQN NWGSLSSSSK LEDGNQAFAG FTSQQKWEDA EILDYEMGIE KNLQAFDQMK  60
PSSGQDNDNN NKNNNSTQAN VDFLQGVKAQ AWDPRTMLSN LSFMEQKIHE LQDLVHLIVG  120
RNGLVAQQQQ QLITTDLTSI IIQLISTAGS LLPSVKHNMS STAPGPYTGS AVFPCPREAN  180
NVASQSQNSN HQRGATQDFD LPKPIVVDER DSHVVEEHEM KDEDDAEEGV ENLPPGSYEI  240
LQLEKEEILA PHTHFCTICG KGFKRDANLR MHMRGHGDEY KTPAALAKPN KEAVPGTEPM  300
LIKRYSCPFP GCKRNKDHKK FQALKTILCV KNHYKRTHCD KSFTCSRCHT KKFSVIADLK  360
THEKHCGKNK WLCSCGTTFS RKDKLFGHIA LFQGHTPAIP LEETKPSAQR GSSEGENNNT  420
GMVGFNLGSA TNADQETEQP GFMEEKISFE ESFSPLSFDT CNFGGFHEFP RPMFDDSESS  480
FQMLISSACG FSPRNGGGGS VSNTIL*

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269\|PubMed:17535918, ECO:0000269\|PubMed:18826429, ECO:0000269\|PubMed:19321711, ECO:0000269\|PubMed:23935008}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00196	ampDAP	Transfer from AT1G34370	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Thhalv10007411m

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269\|PubMed:17535918}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006396064.1	0.0	protein SENSITIVE TO PROTON RHIZOTOXICITY 1 isoform X1
Refseq	XP_006396065.1	0.0	protein SENSITIVE TO PROTON RHIZOTOXICITY 1 isoform X1
Swissprot	Q9C8N5	0.0	STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBL	V4K6X3	0.0	V4K6X3_EUTSA; Uncharacterized protein
STRING	XP_006396064.1	0.0	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6977	26	44

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34370.2	0.0	C2H2 family protein

Link Out ? help Back to Top
Phytozome	Thhalv10007411m
Entrez Gene	18991618

Publications ? help Back to Top
Kobayashi Y, et al. Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions. Plant Physiol., 2013. 163(1): p. 180-92 [PMID:23839867] Yokosho K,Yamaji N,Ma JF Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench). Plant Cell Physiol., 2014. 55(12): p. 2077-91 [PMID:25273892] Geng X, et al. LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis. Plant J., 2017. 90(3): p. 491-504 [PMID:28181322] Balzergue C, et al. Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation. Nat Commun, 2017. 8: p. 15300 [PMID:28504266] Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation. Front Plant Sci, 2017. 8: p. 822 [PMID:28567051] Jiang F, et al. Identification and characterization of suppressor mutants of stop1. BMC Plant Biol., 2017. 17(1): p. 128 [PMID:28738784] Daspute AA, et al. Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms. Front Plant Sci, 2017. 8: p. 1358 [PMID:28848571] Sharma A,Wai CM,Ming R,Yu Q Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis. Genome Biol Evol, 2017. 9(9): p. 2170-2190 [PMID:28922793] Zhang Y, et al. The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis. Front Plant Sci, 2018. 9: p. 118 [PMID:29491872]