PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thhalv10007369m
Common NameEUTSA_v10007369mg
Organism
Eutrema salsugineum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema
Family NAC
Protein Properties Length: 522aa    MW: 58377.9 Da    PI: 6.1661
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thhalv10007369mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM155.91.7e-48171421128
              NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkev 92 
                      l+pGfrFhPtdeelvv+yLk+k+++kk+++ ++i e+d+yk++P++Lp k  +k+++++w+fFs rd+k+  g r++rat +gyWkatgkd+ +
  Thhalv10007369m  17 LAPGFRFHPTDEELVVYYLKRKIRRKKMRV-DAIGETDVYKFDPEELPeKaLYKTRDRQWFFFSLRDRKH--GGRSSRATGRGYWKATGKDRVI 107
                      579***************************.99**************95345667899**********86..89******************** PP

              NAM  93 lskkgelvglkktLvfykgrapkgektdWvmheyrl 128
                      ++ +++ vg kktLvf++grap+ge+t+Wvmhey+l
  Thhalv10007369m 108 KC-SSRPVGEKKTLVFHRGRAPNGERTNWVMHEYTL 142
                      **.999****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019413.4E-5611165IPR003441NAC domain
PROSITE profilePS5100552.47317165IPR003441NAC domain
PfamPF023652.0E-2619142IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010114Biological Processresponse to red light
GO:0010224Biological Processresponse to UV-B
GO:0031930Biological Processmitochondria-nucleus signaling pathway
GO:1900409Biological Processpositive regulation of cellular response to oxidative stress
GO:0005634Cellular Componentnucleus
GO:0005789Cellular Componentendoplasmic reticulum membrane
GO:0016021Cellular Componentintegral component of membrane
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 522 aa     Download sequence    Send to blast
MESLKTGSCL VANGAKLAPG FRFHPTDEEL VVYYLKRKIR RKKMRVDAIG ETDVYKFDPE  60
ELPEKALYKT RDRQWFFFSL RDRKHGGRSS RATGRGYWKA TGKDRVIKCS SRPVGEKKTL  120
VFHRGRAPNG ERTNWVMHEY TLHEEELKRC GDVKESFVLY KIYKKSGSGP KNGEQYGAPF  180
IEEEWADDDD DVVDQLIASA GIGNSALANG LNQTELDDND IEELMRQIRE EPGHVRLSTV  240
QQNNLSRVNS SVETYNQVNQ ARDAYLEIDD LLLSEPEPSY ADNWGQDESG VLNDNDFFDV  300
DSYFRDLDAT GPHLEPVSVG LGNGFEHSLE VNTSSVTDQA NNNQFQQQTG KNQGSNWPLR  360
NSYTRKISSG SWMHELNSDG LTASRFGEAP GTGDAFEFID PLTSGVSITK EVEATKGESS  420
QFASSIWSFL DSIPAKPAFA SENPFVNLNL VRMSSRGGRY RLASKSTGNN NVENDSAAKR  480
KKCRGNNHHK GFFCLSIIGA LCALFWMIIG IIGVSGRSLL W*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3swm_A1e-431717120174NAC domain-containing protein 19
3swm_B1e-431717120174NAC domain-containing protein 19
3swm_C1e-431717120174NAC domain-containing protein 19
3swm_D1e-431717120174NAC domain-containing protein 19
3swp_A1e-431717120174NAC domain-containing protein 19
3swp_B1e-431717120174NAC domain-containing protein 19
3swp_C1e-431717120174NAC domain-containing protein 19
3swp_D1e-431717120174NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Involved in oxidative stress tolerance by mediating regulation of mitochondrial retrograde signaling during mitochondrial dysfunction. Interacts directly with the mitochondrial dysfunction DNA consensus motif 5'-CTTGNNNNNCA[AC]G-3', a cis-regulatory elements of several mitochondrial retrograde regulation-induced genes, and triggers increased oxidative stress tolerance. {ECO:0000269|PubMed:24045019}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00176DAPTransfer from AT1G32870Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapThhalv10007369m
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By heat, salt stress, abscisic acid (ABA) and methyl methanesulfonate (MMS) treatment. {ECO:0000269|PubMed:17158162}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006416168.10.0NAC domain-containing protein 13
SwissprotF4IED20.0NAC13_ARATH; NAC domain-containing protein 13
TrEMBLV4MRY10.0V4MRY1_EUTSA; Uncharacterized protein
STRINGXP_006416168.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM153171517
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G32870.10.0NAC domain protein 13
Publications ? help Back to Top
  1. Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y
    Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress.
    Plant Cell, 2014. 26(12): p. 4656-79
    [PMID:25549671]
  2. O'Shea C, et al.
    Structures and Short Linear Motif of Disordered Transcription Factor Regions Provide Clues to the Interactome of the Cellular Hub Protein Radical-induced Cell Death1.
    J. Biol. Chem., 2017. 292(2): p. 512-527
    [PMID:27881680]