PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema

Family

HD-ZIP

Protein Properties

Length: 844aa MW: 92557.1 Da PI: 6.5826

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thhalv10006792m	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	58.9	8.6e-19	23	81	3	57
--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS Homeobox 3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 k ++t+eq+e+Le++++++++ps +r++L +++ +++ rq+kvWFqNrR +ek+ Thhalv10006792m 23 KYVRYTPEQVEALERVYAECPKPSSLRRQQLIRECpilcNIEPRQIKVWFQNRRCREKQ 81 5678*****************************************************97 PP
2	START	170.7	9.8e-54	172	380	2	205
HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEE CS START 2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galql 93 +aee+++e++ ka+ ++ Wv++ +++g++++ +++ s+++sg a+ra+g+v +++++ve+l d++ W ++++ +etl vi +g g+++l Thhalv10006792m 172 IAEETLAEFLCKATGTAVDWVQMIGMKPGPDSIGIVAVSRNCSGIAARACGLVSLEPMKVVEILKDRP-SWFRDCRCVETLSVIPTGngGTIEL 264 7899****************************************************9999998888.********************* PP EEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHH CS START 94 mvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrs 183 +++ +a+++l++ Rdf+++Ry+ +l++g++v+++ S++s + p+ sss+vRa++l Sg+li+p+++g+s +++v+hvdl+ ++++++lr+ Thhalv10006792m 265 VNTQIYAPTTLAAaRDFWTLRYSTSLEDGSYVVCEKSLTSATGGPNgplSSSFVRAKMLSSGFLIRPCDGGGSIIHIVDHVDLDVSSVPEVLRP 358 *****************************************99******************************************* PP HHHHHHHHHHHHHHHHTXXXXX CS START 184 lvksglaegaktwvatlqrqce 205 l++s+ + ++k++va+l++ ++ Thhalv10006792m 359 LYESSKILAQKMTVAALRHVRQ 380 ***************98765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	6.4E-19	6	81	IPR009057	Homeodomain-like
PROSITE profile	PS50071	15.451	18	82	IPR001356	Homeobox domain
SMART	SM00389	4.2E-16	20	86	IPR001356	Homeobox domain
SuperFamily	SSF46689	1.45E-16	22	84	IPR009057	Homeodomain-like
CDD	cd00086	5.86E-17	23	83	No hit	No description
Pfam	PF00046	2.5E-16	24	81	IPR001356	Homeobox domain
CDD	cd14686	3.23E-6	75	114	No hit	No description
PROSITE profile	PS50848	25.192	162	390	IPR002913	START domain
CDD	cd08875	8.12E-70	166	382	No hit	No description
SMART	SM00234	2.7E-50	171	381	IPR002913	START domain
SuperFamily	SSF55961	1.65E-34	171	383	No hit	No description
Pfam	PF01852	7.7E-51	172	380	IPR002913	START domain
Gene3D	G3DSA:3.30.530.20	9.7E-19	207	376	IPR023393	START-like domain
Pfam	PF08670	1.0E-48	696	842	IPR013978	MEKHLA

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009855	Biological Process	determination of bilateral symmetry
GO:0009880	Biological Process	embryonic pattern specification
GO:0009944	Biological Process	polarity specification of adaxial/abaxial axis
GO:0010072	Biological Process	primary shoot apical meristem specification
GO:0080060	Biological Process	integument development
GO:0003677	Molecular Function	DNA binding
GO:0008289	Molecular Function	lipid binding

Sequence ? help Back to Top
Protein Sequence Length: 844 aa Download sequence Send to blast
MMAHHHHSMD DRDSPDKGFD SGKYVRYTPE QVEALERVYA ECPKPSSLRR QQLIRECPIL 60 CNIEPRQIKV WFQNRRCREK QRKESARLQT VNRKLSAMNK LLMEENDRLQ KQVSHLVYEN 120 GFMKHRIHTA SGTTTDNSCE SVVVSGQQRQ QQNPTHQHPQ RDANNPAGLL SIAEETLAEF 180 LCKATGTAVD WVQMIGMKPG PDSIGIVAVS RNCSGIAARA CGLVSLEPMK VVEILKDRPS 240 WFRDCRCVET LSVIPTGNGG TIELVNTQIY APTTLAAARD FWTLRYSTSL EDGSYVVCEK 300 SLTSATGGPN GPLSSSFVRA KMLSSGFLIR PCDGGGSIIH IVDHVDLDVS SVPEVLRPLY 360 ESSKILAQKM TVAALRHVRQ IAQETSGEVQ YSGGRQPAVL RTFSQRLCRG FNDAVNGFAD 420 DGWSPMSSDG GEDITIMINS SSAKFAGSQY GNSFLPSFGS GVLCAKASML LQNVPPLVLI 480 RFLREHRAEW ADYGVDAYSA ASLRATPFAV PCVRTGGFPS NQVILPLAQT LEHEEFLEVV 540 RLGGHAYSPE DMGLSRDMYL LQLCSGVDEN VVGGCAQLVF APIDESFADD APLLPSGFRV 600 IPLEQKTTPS DHVSANRTRD LASSLDGSTK TDSETNSRLV LTIAFQFTFD NHSRDNVATM 660 ARQYVRNVVG SIQRVALAIT PRPGSMQLPT SPEALTLVRW ISRSYSIHTG ANLLGAESQA 720 CDGDTLLKQL WNHADAILCC SLKTNASPVF TFANQAGLDM LETTLVALQD IMLDKTLNDS 780 GRKALCSEFA KIMQQGYANL PAGICVSSMG RPVSYEQATV WKVLDDDESN HCLAFILVNW 840 SFV*

Sequence ? help Back to Top

Protein Sequence Length: 844 aa Download sequence Send to blast

MMAHHHHSMD DRDSPDKGFD SGKYVRYTPE QVEALERVYA ECPKPSSLRR QQLIRECPIL  60
CNIEPRQIKV WFQNRRCREK QRKESARLQT VNRKLSAMNK LLMEENDRLQ KQVSHLVYEN  120
GFMKHRIHTA SGTTTDNSCE SVVVSGQQRQ QQNPTHQHPQ RDANNPAGLL SIAEETLAEF  180
LCKATGTAVD WVQMIGMKPG PDSIGIVAVS RNCSGIAARA CGLVSLEPMK VVEILKDRPS  240
WFRDCRCVET LSVIPTGNGG TIELVNTQIY APTTLAAARD FWTLRYSTSL EDGSYVVCEK  300
SLTSATGGPN GPLSSSFVRA KMLSSGFLIR PCDGGGSIIH IVDHVDLDVS SVPEVLRPLY  360
ESSKILAQKM TVAALRHVRQ IAQETSGEVQ YSGGRQPAVL RTFSQRLCRG FNDAVNGFAD  420
DGWSPMSSDG GEDITIMINS SSAKFAGSQY GNSFLPSFGS GVLCAKASML LQNVPPLVLI  480
RFLREHRAEW ADYGVDAYSA ASLRATPFAV PCVRTGGFPS NQVILPLAQT LEHEEFLEVV  540
RLGGHAYSPE DMGLSRDMYL LQLCSGVDEN VVGGCAQLVF APIDESFADD APLLPSGFRV  600
IPLEQKTTPS DHVSANRTRD LASSLDGSTK TDSETNSRLV LTIAFQFTFD NHSRDNVATM  660
ARQYVRNVVG SIQRVALAIT PRPGSMQLPT SPEALTLVRW ISRSYSIHTG ANLLGAESQA  720
CDGDTLLKQL WNHADAILCC SLKTNASPVF TFANQAGLDM LETTLVALQD IMLDKTLNDS  780
GRKALCSEFA KIMQQGYANL PAGICVSSMG RPVSYEQATV WKVLDDDESN HCLAFILVNW  840
SFV*

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in the determination of adaxial-abaxial polarity in ovule primordium. Specifies adaxial leaf fates. Binds to the DNA sequence 5'-GTAAT[GC]ATTAC-3'. {ECO:0000269\|PubMed:11395776, ECO:0000269\|PubMed:15598805, ECO:0000269\|PubMed:17900520, ECO:0000269\|PubMed:9747806}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00170	DAP	Transfer from AT1G30490	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Thhalv10006792m

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By auxin. Repressed by miR165 and miR166. {ECO:0000269\|PubMed:14999284, ECO:0000269\|PubMed:16033795, ECO:0000269\|PubMed:17237362}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK353258	0.0	AK353258.1 Thellungiella halophila mRNA, complete cds, clone: RTFL01-39-H09.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006415465.2	0.0	homeobox-leucine zipper protein ATHB-9
Swissprot	O04292	0.0	ATBH9_ARATH; Homeobox-leucine zipper protein ATHB-9
TrEMBL	E4MXL1	0.0	E4MXL1_EUTHA; mRNA, clone: RTFL01-39-H09
STRING	XP_006415465.1	0.0	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4256	26	53

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G30490.1	0.0	HD-ZIP family protein

Link Out ? help Back to Top
Phytozome	Thhalv10006792m

Publications ? help Back to Top
Jia X, et al. Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic. Plant Sci., 2015. 233: p. 11-21 [PMID:25711809] Yamada T,Sasaki Y,Hashimoto K,Nakajima K,Gasser CS CORONA, PHABULOSA and PHAVOLUTA collaborate with BELL1 to confine WUSCHEL expression to the nucellus in Arabidopsis ovules. Development, 2016. 143(3): p. 422-6 [PMID:26700684] Wójcik AM,Nodine MD,Gaj MD miR160 and miR166/165 Contribute to the LEC2-Mediated Auxin Response Involved in the Somatic Embryogenesis Induction in Arabidopsis. Front Plant Sci, 2017. 8: p. 2024 [PMID:29321785]