PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thhalv10004406m
Common NameEUTSA_v10004407mg
Organism
Eutrema salsugineum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema
Family MYB
Protein Properties Length: 379aa    MW: 42146.7 Da    PI: 6.1545
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thhalv10004406mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding58.81.2e-181461148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     +g+WTteEd++l+ +++++G g W+ I+++ g++R++k+c++rw +yl
  Thhalv10004406m 14 KGAWTTEEDKKLISYIHEHGEGGWRDIPQKAGLKRCGKSCRLRWTNYL 61
                     79********************************************97 PP
2Myb_DNA-binding482.9e-1567112148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      rg ++ eE+++++ +++  G++ W+ Iar+++ +Rt++++k++w+++l
  Thhalv10004406m  67 RGEFSSEEEQIIIMLHASRGNK-WSVIARHLP-RRTDNEIKNYWNTHL 112
                      899*******************.*********.************996 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.603.3E-24564IPR009057Homeodomain-like
PROSITE profilePS5129424.586965IPR017930Myb domain
SuperFamilySSF466899.87E-2911108IPR009057Homeodomain-like
SMARTSM007171.6E-141363IPR001005SANT/Myb domain
PfamPF002492.2E-171461IPR001005SANT/Myb domain
CDDcd001673.38E-111661No hitNo description
Gene3DG3DSA:1.10.10.605.1E-2565117IPR009057Homeodomain-like
PROSITE profilePS5129419.75366116IPR017930Myb domain
SMARTSM007172.5E-1466114IPR001005SANT/Myb domain
PfamPF002491.4E-1367112IPR001005SANT/Myb domain
CDDcd001672.34E-1069112No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009625Biological Processresponse to insect
GO:0009682Biological Processinduced systemic resistance
GO:0009739Biological Processresponse to gibberellin
GO:0009751Biological Processresponse to salicylic acid
GO:0009753Biological Processresponse to jasmonic acid
GO:0010439Biological Processregulation of glucosinolate biosynthetic process
GO:0050832Biological Processdefense response to fungus
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 379 aa     Download sequence    Send to blast
MSRKPCCVGE GLKKGAWTTE EDKKLISYIH EHGEGGWRDI PQKAGLKRCG KSCRLRWTNY  60
LKPEIKRGEF SSEEEQIIIM LHASRGNKWS VIARHLPRRT DNEIKNYWNT HLKKRLVEQG  120
LDPVTHKPIA SSSNPTVTTP PENLHSLAAS SSDKQYSRSS SMPSLSRPPT SGFNTVSEVS  180
EITSNVWTPV QDGSLGCKKR FKKSSSTSRL LNKVAAKATS IKDILSASME GSLSATTISH  240
TSFFNGFSEQ IRSEEDNSNA SLTNTLAGFD PFSQSSLYPE HEINATSDLG MDAQGYDFSH  300
FLEKLGGDNH NEENNINIMN VEYGHDLLMS DVSQEVSSTS VDDQDNMTGN LEGWSNYLID  360
HADFIYDAES ESLEKHFI*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h8a_C1e-241211625128MYB TRANSFORMING PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtMajor regulator of short-chained aliphatic glucosinolates (GLSs) biosynthesis. Together with MYB29/HAG3 and MYB76/HAG2, promotes aliphatic glucosinolate biosynthesis but represses indolic glucosinolate biosynthesis. Prevents insect performance (e.g. lepidopteran insect Mamestra brassicae and Spodoptera exigua) by promoting glucosinolates. {ECO:0000269|PubMed:17420480, ECO:0000269|PubMed:17521412, ECO:0000269|PubMed:18042203, ECO:0000269|PubMed:18446225, ECO:0000269|PubMed:20348214, ECO:0000269|PubMed:23580754, ECO:0000269|PubMed:23792303, ECO:0000269|PubMed:23943862}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapThhalv10004406m
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Slightly induced by glucose, gibberellic acid (GA), jasmonic acid (JA) and salicylic acid (SA). Transiently induced in inflorescence by mechanical stimuli such as touch or wounding, including herbivory-wounding. Up-regulated by sulfur-deficient stress. {ECO:0000269|PubMed:16463103, ECO:0000269|PubMed:17521412, ECO:0000269|PubMed:23115560, ECO:0000269|PubMed:23792303}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF1759980.0AF175998.1 Arabidopsis thaliana putative transcription factor (MYB28) mRNA, complete cds.
GenBankAY5196430.0AY519643.1 Arabidopsis thaliana MYB transcription factor (At5g61420) mRNA, complete cds.
GenBankBT0289590.0BT028959.1 Arabidopsis thaliana At5g61420 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006394507.10.0transcription factor MYB28
RefseqXP_024006941.10.0transcription factor MYB28
SwissprotQ9SPG20.0MYB28_ARATH; Transcription factor MYB28
TrEMBLV4KWQ20.0V4KWQ2_EUTSA; Uncharacterized protein
STRINGXP_006394507.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM37871860
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G61420.20.0myb domain protein 28
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Kim K,Jiang K,Teng SL,Feldman LJ,Huang H
    Using biologically interrelated experiments to identify pathway genes in Arabidopsis.
    Bioinformatics, 2012. 28(6): p. 815-22
    [PMID:22271267]
  3. Augustine R,Majee M,Gershenzon J,Bisht NC
    Four genes encoding MYB28, a major transcriptional regulator of the aliphatic glucosinolate pathway, are differentially expressed in the allopolyploid Brassica juncea.
    J. Exp. Bot., 2013. 64(16): p. 4907-21
    [PMID:24043856]
  4. Guo R, et al.
    Jasmonic acid and glucose synergistically modulate the accumulation of glucosinolates in Arabidopsis thaliana.
    J. Exp. Bot., 2013. 64(18): p. 5707-19
    [PMID:24151308]
  5. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  6. Li F, et al.
    Genome-wide association study dissects the genetic architecture of seed weight and seed quality in rapeseed (Brassica napus L.).
    DNA Res., 2014. 21(4): p. 355-67
    [PMID:24510440]
  7. Frerigmann H,Gigolashvili T
    Update on the role of R2R3-MYBs in the regulation of glucosinolates upon sulfur deficiency.
    Front Plant Sci, 2014. 5: p. 626
    [PMID:25426131]
  8. Burow M, et al.
    The Glucosinolate Biosynthetic Gene AOP2 Mediates Feed-back Regulation of Jasmonic Acid Signaling in Arabidopsis.
    Mol Plant, 2015. 8(8): p. 1201-12
    [PMID:25758208]
  9. Martínez-Ballesta M, et al.
    The impact of the absence of aliphatic glucosinolates on water transport under salt stress in Arabidopsis thaliana.
    Front Plant Sci, 2015. 6: p. 524
    [PMID:26236322]
  10. Seo MS, et al.
    Functional analysis of three BrMYB28 transcription factors controlling the biosynthesis of glucosinolates in Brassica rapa.
    Plant Mol. Biol., 2016. 90(4-5): p. 503-16
    [PMID:26820138]
  11. Bulgakov VP,Veremeichik GN,Grigorchuk VP,Rybin VG,Shkryl YN
    The rolB gene activates secondary metabolism in Arabidopsis calli via selective activation of genes encoding MYB and bHLH transcription factors.
    Plant Physiol. Biochem., 2016. 102: p. 70-9
    [PMID:26913794]
  12. Mostafa I, et al.
    New nodes and edges in the glucosinolate molecular network revealed by proteomics and metabolomics of Arabidopsis myb28/29 and cyp79B2/B3 glucosinolate mutants.
    J Proteomics, 2016. 138: p. 1-19
    [PMID:26915584]
  13. Smith JD,Woldemariam MG,Mescher MC,Jander G,De Moraes CM
    Glucosinolates from Host Plants Influence Growth of the Parasitic Plant Cuscuta gronovii and Its Susceptibility to Aphid Feeding.
    Plant Physiol., 2016. 172(1): p. 181-97
    [PMID:27482077]
  14. Aarabi F, et al.
    Sulfur deficiency-induced repressor proteins optimize glucosinolate biosynthesis in plants.
    Sci Adv, 2016. 2(10): p. e1601087
    [PMID:27730214]
  15. Mostafa I, et al.
    Membrane Proteomics of Arabidopsis Glucosinolate Mutants cyp79B2/B3 and myb28/29.
    Front Plant Sci, 2017. 8: p. 534
    [PMID:28443122]
  16. Simon MK,Skinner DJ,Gallagher TL,Gasser CS
    Integument Development in Arabidopsis Depends on Interaction of YABBY Protein INNER NO OUTER with Coactivators and Corepressors.
    Genetics, 2017. 207(4): p. 1489-1500
    [PMID:28971961]
  17. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]