PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Thhalv10004105m

Common Name

EUTSA_v10004105mg

Organism

Eutrema salsugineum

Taxonomic ID

72664

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema

Family

NAC

Protein Properties

Length: 484aa MW: 53946.9 Da PI: 5.0961

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thhalv10004105m	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	162.8	1.3e-50	9	137	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp..kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkev 92 lp+GfrF+Ptdeelv++yL+ k++g++ ++ +vi+evdi+k+ePwdLp + vk++++ew fF++ d+ky++g+r nrat +gyWkatgkd++v Thhalv10004105m 9 LPVGFRFSPTDEELVKYYLRLKINGHDDDV-RVIREVDICKWEPWDLPdfSVVKTTDSEWLFFCPLDRKYPSGSRMNRATVAGYWKATGKDRKV 101 79***********************999.99***********6447888999******************************** PP NAM 93 lskkgelvglkktLvfykgrapkgektdWvmheyrl 128 +s +++ +g+k+tLvfy+grapkg++t W+mheyr+ Thhalv10004105m 102 KSGNTKIIGVKRTLVFYTGRAPKGSRTCWIMHEYRA 137 99******************************96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	7.45E-57	4	160	IPR003441	NAC domain
PROSITE profile	PS51005	54.849	9	160	IPR003441	NAC domain
Pfam	PF02365	6.5E-25	10	136	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0002230	Biological Process	positive regulation of defense response to virus by host
GO:0002237	Biological Process	response to molecule of bacterial origin
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0003713	Molecular Function	transcription coactivator activity
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 484 aa Download sequence Send to blast
MEVLSLASLP VGFRFSPTDE ELVKYYLRLK INGHDDDVRV IREVDICKWE PWDLPDFSVV 60 KTTDSEWLFF CPLDRKYPSG SRMNRATVAG YWKATGKDRK VKSGNTKIIG VKRTLVFYTG 120 RAPKGSRTCW IMHEYRATEK DLDGTKSGQN PFVICKLFKK QDVVNGAAPE DLKSSEVEPA 180 VSSPAVVDEM KSEVELSEVS LVFPKTDDDD AKPSDNGESS LVVSGECHSE NSAPEVTTTE 240 LDHIDWQSYL ELESLDCNLY SPLHSQVQSE LGFQSGSNDL FSNQSVAHIQ TQYGTNDADE 300 MMFELLESAL EIPYEFPETK HLALPTLEQS TYEPQNPVNI CNMINDVSGT GIKIRARRTQ 360 APGCAEQFVM QGDASRRLRL QVNHNSQKPE TVKKEVMDTA RETITKGCGN FMRWNSRSGF 420 IFKKIAAMGC SYKGLFSAGV VAVVFAMSVS TKTIAETESI SSKAYYQNDR IKVFGLESSV 480 IAL*

Sequence ? help Back to Top

Protein Sequence Length: 484 aa Download sequence Send to blast

MEVLSLASLP VGFRFSPTDE ELVKYYLRLK INGHDDDVRV IREVDICKWE PWDLPDFSVV  60
KTTDSEWLFF CPLDRKYPSG SRMNRATVAG YWKATGKDRK VKSGNTKIIG VKRTLVFYTG  120
RAPKGSRTCW IMHEYRATEK DLDGTKSGQN PFVICKLFKK QDVVNGAAPE DLKSSEVEPA  180
VSSPAVVDEM KSEVELSEVS LVFPKTDDDD AKPSDNGESS LVVSGECHSE NSAPEVTTTE  240
LDHIDWQSYL ELESLDCNLY SPLHSQVQSE LGFQSGSNDL FSNQSVAHIQ TQYGTNDADE  300
MMFELLESAL EIPYEFPETK HLALPTLEQS TYEPQNPVNI CNMINDVSGT GIKIRARRTQ  360
APGCAEQFVM QGDASRRLRL QVNHNSQKPE TVKKEVMDTA RETITKGCGN FMRWNSRSGF  420
IFKKIAAMGC SYKGLFSAGV VAVVFAMSVS TKTIAETESI SSKAYYQNDR IKVFGLESSV  480
IAL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	1e-45	4	161	12	166	NO APICAL MERISTEM PROTEIN
1ut4_B	1e-45	4	161	12	166	NO APICAL MERISTEM PROTEIN
1ut7_A	1e-45	4	161	12	166	NO APICAL MERISTEM PROTEIN
1ut7_B	1e-45	4	161	12	166	NO APICAL MERISTEM PROTEIN
3swm_A	2e-45	4	161	15	169	NAC domain-containing protein 19
3swm_B	2e-45	4	161	15	169	NAC domain-containing protein 19
3swm_C	2e-45	4	161	15	169	NAC domain-containing protein 19
3swm_D	2e-45	4	161	15	169	NAC domain-containing protein 19
3swp_A	2e-45	4	161	15	169	NAC domain-containing protein 19
3swp_B	2e-45	4	161	15	169	NAC domain-containing protein 19
3swp_C	2e-45	4	161	15	169	NAC domain-containing protein 19
3swp_D	2e-45	4	161	15	169	NAC domain-containing protein 19
4dul_A	1e-45	4	161	12	166	NAC domain-containing protein 19
4dul_B	1e-45	4	161	12	166	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator essential for the anti-viral defense called virus basal resistance response pathway (PubMed:11041886, PubMed:15629774, PubMed:18785827, PubMed:24418554). Not involved in HRT-mediated hypersensitive response (HR) and resistance to TCV (PubMed:18785827). Binds DNA non specifically (PubMed:15629774). Activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (By similarity). {ECO:0000250\|UniProtKB:Q9SCK6, ECO:0000269\|PubMed:11041886, ECO:0000269\|PubMed:15629774, ECO:0000269\|PubMed:18785827, ECO:0000269\|PubMed:24418554}.; FUNCTION: (Microbial infection) Compromised function in defense response pathway when interacting with the invading viral capsid protein (CP) of turnip crinkle virus (TCV) due to abnormal subcellular localization. {ECO:0000269\|PubMed:11041886, ECO:0000269\|PubMed:15629774}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Thhalv10004105m

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by bacterial pathogens type III effector proteins (TTEs). {ECO:0000269\|PubMed:16553893}.; INDUCTION: (Microbial infection) Accumulates 2 days post infection with turnip crinkle virus (TCV) (PubMed:24418554). {ECO:0000269\|PubMed:24418554}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024007342.1	0.0	NAC domain-containing protein 91 isoform X2
Swissprot	Q9LKG8	0.0	NAC91_ARATH; NAC domain-containing protein 91
TrEMBL	V4K3F8	0.0	V4K3F8_EUTSA; Uncharacterized protein
STRING	XP_006394714.1	0.0	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2416	28	73

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G24590.2	0.0	TCV-interacting protein

Link Out ? help Back to Top
Phytozome	Thhalv10004105m
Entrez Gene	18013055

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ben Daniel BH, et al. Identification of novel transcriptional regulators of Zat12 using comprehensive yeast one-hybrid screens. Physiol Plant, 2016. 157(4): p. 422-41 [PMID:26923089] Li Y, et al. The interaction between Turnip crinkle virus p38 and Cucumber mosaic virus 2b and its critical domains. Virus Res., 2016. 222: p. 94-105 [PMID:27288723]