PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thhalv10001877m
Common NameEUTSA_v10001877mg
Organism
Eutrema salsugineum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema
Family C3H
Protein Properties Length: 1604aa    MW: 178662 Da    PI: 4.6668
Description C3H family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thhalv10001877mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-CCCH25.42.5e-0815791602225
                       -S---SGGGGTS--TTTTT-SS-S CS
          zf-CCCH    2 ktelCrffartGtCkyGdrCkFaH 25  
                       +++ C+f++++G+C+ G++C++ H
  Thhalv10001877m 1579 GQRVCKFYQENGHCRKGASCNYLH 1602
                       6899******************** PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF579032.44E-8440513IPR011011Zinc finger, FYVE/PHD-type
Gene3DG3DSA:3.30.40.107.6E-10460520IPR013083Zinc finger, RING/FYVE/PHD-type
PROSITE profilePS500168.609464530IPR019787Zinc finger, PHD-finger
CDDcd155685.71E-21466511No hitNo description
SMARTSM002491.3E-7466512IPR001965Zinc finger, PHD-type
PROSITE patternPS013590467527IPR019786Zinc finger, PHD-type, conserved site
Gene3DG3DSA:1.10.245.103.2E-24662755IPR003121SWIB/MDM2 domain
SuperFamilySSF475923.71E-21666752IPR003121SWIB/MDM2 domain
SMARTSM001510.007668752IPR019835SWIB domain
PfamPF022012.8E-13689747IPR003121SWIB/MDM2 domain
SMARTSM007194.0E-50809918IPR004343Plus-3 domain
SuperFamilySSF1590426.67E-33809938IPR004343Plus-3 domain
PROSITE profilePS5136028.489809941IPR004343Plus-3 domain
PfamPF031263.6E-23814916IPR004343Plus-3 domain
SuperFamilySSF552773.53E-1711411207IPR003169GYF domain
PROSITE profilePS5082915.26511541208IPR003169GYF domain
CDDcd000721.38E-1711541211No hitNo description
SMARTSM004444.8E-2111551210IPR003169GYF domain
Gene3DG3DSA:3.30.1490.406.4E-1611551208IPR003169GYF domain
PfamPF022135.9E-1311561196IPR003169GYF domain
PROSITE profilePS5010314.94315771603IPR000571Zinc finger, CCCH-type
PfamPF006426.9E-615791602IPR000571Zinc finger, CCCH-type
Gene3DG3DSA:4.10.1000.102.1E-515811603IPR000571Zinc finger, CCCH-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
GO:0008270Molecular Functionzinc ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 1604 aa     Download sequence    Send to blast
MKFAPLEGGK EERNQKRKGD SVAECRVKRI HFQEKNKEVS MEEEPPPSQD ISASGVNGVD  60
SLKVEEKREE ESTQAVKIEL GNTESEKEKF DVMEEETTAQ AASLEDIVSV DLKIPDEKEI  120
ASVAGFTEIP SQDEKSLEEL QMGQGAKDLS DEFAKEDVGF TVDAMGNQVL KETEEEEEKP  180
DAVTVLETQA KLQEEDDEVN EVSEKNKAPM SDSSAGKEDV EKDLEVGNSV EIHVPEAAQE  240
VETDVKYAAG IEEEGDGMDG VRDVRQTADL EETRELSEEL AKADETKIAE VSEETETIIE  300
EENEEKNDDM TDLAEDVETH KDYSAALSEE GRDDHEEMGM KEMIKTQEEA VVGKVDRAKV  360
AEMSEETQTR MEVEDEEKDE DMNDVAEDVE THRDSSATDI EEESENNDEI EMTDPTDTQE  420
EIVMGETRDE ELEEVEEENK SAKGKRKRVR NTKTVKGTGK KKEEDVCFMC FDGGDLVLCD  480
RRGCPKAYHP SCVDRDEAFF RSKGNWNCGW HLCSKCEKTA TYLCYTCMFS LCKCCAKDAV  540
FFCVRGNKGL CETCMETVKL IEKKEQEKEP AQLDFDDKTS WEYLFKDYWL DLKSQLSLSP  600
EELDQAKSPQ KGNESHAGKQ GITRETDYVT DGGSDSDSSP KKRKTRSRLK SSSAEKILSP  660
ANKSSSGETM KWASKELLDV VAHMRRGDIS FLPHSEVHAL LLDYIKRYNL RDPRRKSQVI  720
CDSKLQNLFG KSHVGHFEML NLLDTHFLDK EQQQVNDIQG SIDDTEPDHV DVDENFGHPV  780
KSGKDKKRKT RKKSVRKGGC QSNLDDFAAI DMHNINLIYL RRSLVEDLLG DSTAFEEKVT  840
SAFVRLKIPG IQKQDLYRLV QVIGTPKAPE PYKVGKKTTD FELEILNLDK KEVISIDVIS  900
NQDFTEDECM RLKQSIKCGL INRLSMGDIQ EKAIALQEVR IKNLLEAEIL RFSHLRDRAS  960
DMGHRKELRE CVERLQKLKS PEERQRRLEE IPGIHGDPKM DPNCESEDED GKEEKEKERN  1020
MRPRSSSFNR RGRDPISPRR GGFSSNESWT STSNFSNNRE LSRSYSSRGS TGREDYLGSS  1080
EENVSESMWT LGRKREMPQS SGSEKPRSVS IPEPAPRSSH TIVQPELSPR IVPENLTAPP  1140
AVVPQPAPMS NESEKMWHYK DPSGKVQGSF SMAQLRKWNN TGYFPAKLEI WKATESPLDS  1200
ILLTDALAGL FQKQTQPVDN SYEKSQVAAY SGQPSQTAPS ILDIPRNSQD TWSSGGSLPS  1260
PTPNQITTPT AKRRNFESRW SPTKPSAQSC DQSINMSLAQ SGPSQVSRTD IPMVVNSAGA  1320
LQPNTHRIPG TDMTNSSNNH YGSAPTLPSP TPAGGKQSWS NMQTYKFDSH GRGGGEAPSS  1380
SASYVTATPS ILPSQSQQGY PQSDPWRVPI PSQPNTQSQA RANNEPWGMN NSQNAGQPQA  1440
PQSNQNSGWG QGTVDPNMGW AGPVQAGMNV NWAAPSVPPT GQGMPNPGWG GSVQAKPQPQ  1500
AYPNTGWGTV AGQGQAPGST TGSGWMQPGQ GMQPGNSNQN WGTQNQIAIP SWGNQQNQNR  1560
DSGGYGWNRQ SSGQNNFKGQ RVCKFYQENG HCRKGASCNY LHN*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4gnd_A4e-15451533281Histone-lysine N-methyltransferase NSD3
4gnd_C4e-15451533281Histone-lysine N-methyltransferase NSD3
4gne_A4e-15451533281Histone-lysine N-methyltransferase NSD3
4gnf_A4e-15451533281Histone-lysine N-methyltransferase NSD3
4gng_A4e-15451533281Histone-lysine N-methyltransferase NSD3
4gng_D4e-15451533281Histone-lysine N-methyltransferase NSD3
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtPlays a central role in integrating RNA silencing and chromatin signals in 21 nt siRNA-dependent DNA methylation on cytosine pathway leading to transcriptional gene silencing of specific sequences. Involved in a chromatin-based RNA silencing pathway that encompasses both post-transcriptional gene silencing (PTGS) (e.g. RDR1, RDR6 and AGO2) and transcriptional gene silencing (TGS) (e.g. siRNA-dependent DNA methylation and histone H3) components. Mediates siRNA accumulation at specific chromatin loci. Binds H3K4me0 through its PHD to enforce low levels of H3K4 methylation and gene silencing at a subset of genomic loci. {ECO:0000269|PubMed:22940247}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapThhalv10001877m
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0070470.0AC007047.7 Arabidopsis thaliana chromosome 2 clone F16F14 map mi398, complete sequence.
GenBankCP0026850.0CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006408927.10.0zinc finger CCCH domain-containing protein 19
SwissprotQ9SIV50.0C3H19_ARATH; Zinc finger CCCH domain-containing protein 19
TrEMBLV4LIL80.0V4LIL8_EUTSA; Uncharacterized protein
STRINGXP_006408927.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM54221620
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G16485.10.0nucleic acid binding;zinc ion binding;DNA binding