PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema

Family

WRKY

Protein Properties

Length: 350aa MW: 39192.3 Da PI: 6.6792

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thhalv10001802m	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	105.5	2.8e-33	187	243	2	58
--SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnh 58 +Dgy+WrKYGqK vk+s+fprsYYrCt+a+C+vkk+vers +dp++v++tYeg+H+h Thhalv10001802m 187 EDGYRWRKYGQKAVKNSPFPRSYYRCTTASCNVKKRVERSFRDPSTVVTTYEGQHTH 243 8******************************************************** PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PIRSF	PIRSF038130	2.2E-116	1	349	IPR017396	PWRKY transcription factor, group IIc
Gene3D	G3DSA:2.20.25.80	8.4E-34	171	245	IPR003657	WRKY domain
SuperFamily	SSF118290	1.83E-28	178	244	IPR003657	WRKY domain
PROSITE profile	PS50811	30.963	181	246	IPR003657	WRKY domain
SMART	SM00774	1.0E-38	186	245	IPR003657	WRKY domain
Pfam	PF03106	8.1E-26	187	243	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009624	Biological Process	response to nematode
GO:0009733	Biological Process	response to auxin
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 350 aa Download sequence Send to blast
MEFTDFSKTS LYHPSSQSIW DFGDFAAAER NSLGFMELLG AQHHHQLQDF ATTPSPQSFL 60 LETPQPQTQT QPSAKLSSSV STILQAPTSD ATAEKLVASK VESLCSEHLL INPPATPNSS 120 SISSASSEAV YEEKAKREDE EEDEEEHEHE KKKSDTNKQL KPKKNNQKRQ REARVAFMTK 180 SEVDHLEDGY RWRKYGQKAV KNSPFPRSYY RCTTASCNVK KRVERSFRDP STVVTTYEGQ 240 HTHISPLTSR PISTGGFFGS TGAVSNLGNF GFPVENSTLI SPQFQQLVHN YHHQQQQQEL 300 LSCFGGVSEY LNSHAIGYGD DDRVKKSRGL VKDYGLLQDV VPSHMLKEE*

Sequence ? help Back to Top

Protein Sequence Length: 350 aa Download sequence Send to blast

MEFTDFSKTS LYHPSSQSIW DFGDFAAAER NSLGFMELLG AQHHHQLQDF ATTPSPQSFL  60
LETPQPQTQT QPSAKLSSSV STILQAPTSD ATAEKLVASK VESLCSEHLL INPPATPNSS  120
SISSASSEAV YEEKAKREDE EEDEEEHEHE KKKSDTNKQL KPKKNNQKRQ REARVAFMTK  180
SEVDHLEDGY RWRKYGQKAV KNSPFPRSYY RCTTASCNVK KRVERSFRDP STVVTTYEGQ  240
HTHISPLTSR PISTGGFFGS TGAVSNLGNF GFPVENSTLI SPQFQQLVHN YHHQQQQQEL  300
LSCFGGVSEY LNSHAIGYGD DDRVKKSRGL VKDYGLLQDV VPSHMLKEE*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	1e-27	176	246	7	77	Probable WRKY transcription factor 4
2lex_A	1e-27	176	246	7	77	Probable WRKY transcription factor 4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00069	PBM	Transfer from AT2G47260	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Thhalv10001802m

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK117918	0.0	AK117918.1 Arabidopsis thaliana At2g47260 mRNA for putative WRKY-type DNA binding protein, complete cds, clone: RAFL19-10-C13.
GenBank	AY052647	0.0	AY052647.1 Arabidopsis thaliana WRKY transcription factor 23 (WRKY23) mRNA, complete cds.
GenBank	BT006238	0.0	BT006238.1 Arabidopsis thaliana At2g47260 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006397921.1	0.0	probable WRKY transcription factor 23
Swissprot	O22900	1e-170	WRK23_ARATH; WRKY transcription factor 23
TrEMBL	V4L6S1	0.0	V4L6S1_EUTSA; Uncharacterized protein
STRING	XP_006397921.1	0.0	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6152	26	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G47260.1	1e-156	WRKY DNA-binding protein 23

Link Out ? help Back to Top
Phytozome	Thhalv10001802m
Entrez Gene	18015666

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Guo D,Qin G EXB1/WRKY71 transcription factor regulates both shoot branching and responses to abiotic stresses. Plant Signal Behav, 2016. 11(3): p. e1150404 [PMID:26914912] Prát T, et al. WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity. PLoS Genet., 2018. 14(1): p. e1007177 [PMID:29377885]