PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma

Family

MYB

Protein Properties

Length: 299aa MW: 33733.8 Da PI: 6.9022

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thecc1EG037376t1	genome	CGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	47.4	4.5e-15	14	61	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg+WT+ Ed++l ++k +G g W+ +++ g++R++k+c++rw++yl Thecc1EG037376t1 14 RGAWTALEDKILTAYIKAHGEGKWRNLPKRAGLKRCGKSCRLRWLNYL 61 89********************************************97 PP
2	Myb_DNA-binding	50.7	4.1e-16	67	111	1	47
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 rg+ + +E+el+++++++lG++ W++Ia +++ gRt++++k++w++ Thecc1EG037376t1 67 RGNISHDEEELIIRLHNLLGNR-WSLIAGRLP-GRTDNEIKNYWNTT 111 78999***************.*****.**********87 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	1.3E-22	5	64	IPR009057	Homeodomain-like
PROSITE profile	PS51294	14.991	9	61	IPR017930	Myb domain
SuperFamily	SSF46689	1.3E-27	12	108	IPR009057	Homeodomain-like
SMART	SM00717	1.7E-12	13	63	IPR001005	SANT/Myb domain
Pfam	PF00249	4.0E-13	14	61	IPR001005	SANT/Myb domain
CDD	cd00167	4.03E-9	16	61	No hit	No description
PROSITE profile	PS51294	24.17	62	116	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	1.7E-23	65	115	IPR009057	Homeodomain-like
SMART	SM00717	6.5E-15	66	114	IPR001005	SANT/Myb domain
Pfam	PF00249	2.7E-14	67	111	IPR001005	SANT/Myb domain
CDD	cd00167	4.40E-11	71	112	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 299 aa Download sequence Send to blast
MGRSPCCSKE GLNRGAWTAL EDKILTAYIK AHGEGKWRNL PKRAGLKRCG KSCRLRWLNY 60 LRPDIKRGNI SHDEEELIIR LHNLLGNRWS LIAGRLPGRT DNEIKNYWNT TLGKRAKAKA 120 SSPTSTETPH SKSRHKKLTT QPHVTDPSNS PQATETKIQV IRTKATRCSS KVLVPLQPPP 180 IQDIDPSEHQ DFQPYLTNHE EMNNNASVQS HHGTEVLDAL YSHGQDFLNF EINDQLRASN 240 EDSEESNDIN KNPSLDPVQP LSIDEAMFKD WTTNPCLDDN AAMDLDSLAF LLEPDEWP*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h8a_C	2e-23	12	116	25	128	MYB TRANSFORMING PROTEIN
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Functional Description ? help Back to Top
Source	Description
UniProt	Controls the expression of genes involved in anthocyanin biosynthesis. Regulates the expression of at least 3 structural genes: chalcone synthase, dihydroflavonol reductase and flavonol O(3) glucosyltransferase. C1 acts as a trans-acting factor.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF336284	1e-123	AF336284.1 Gossypium hirsutum GHMYB36 (ghmyb36) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_007012408.1	0.0	PREDICTED: myb-related protein 308
Swissprot	P10290	2e-64	MYBC_MAIZE; Anthocyanin regulatory C1 protein
TrEMBL	A0A061GLK4	0.0	A0A061GLK4_THECC; Duplicated homeodomain-like superfamily protein
STRING	EOY30027	0.0	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4	28	2646

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G16720.1	5e-64	myb domain protein 7

Link Out ? help Back to Top
Phytozome	Thecc1EG037376t1
Entrez Gene	18588141

Publications ? help Back to Top
Chen B,Wang X,Hu Y,Wang Y,Lin Z Ectopic expression of a c1-I allele from maize inhibits pigment formation in the flower of transgenic tobacco. Mol. Biotechnol., 2004. 26(3): p. 187-92 [PMID:15004287] Paz-Ares J,Ghosal D,Saedler H Molecular analysis of the C1-I allele from Zea mays: a dominant mutant of the regulatory C1 locus. EMBO J., 1990. 9(2): p. 315-21 [PMID:2303027] Motamayor JC, et al. The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color. Genome Biol., 2013. 14(6): p. r53 [PMID:23731509] Cone KC,Burr FA,Burr B Molecular analysis of the maize anthocyanin regulatory locus C1. Proc. Natl. Acad. Sci. U.S.A., 1986. 83(24): p. 9631-5 [PMID:3025847] Paz-Ares J,Ghosal D,Wienand U,Peterson PA,Saedler H The regulatory c1 locus of Zea mays encodes a protein with homology to myb proto-oncogene products and with structural similarities to transcriptional activators. EMBO J., 1987. 6(12): p. 3553-8 [PMID:3428265] Scheffler B, et al. Molecular analysis of C1 alleles in Zea mays defines regions involved in the expression of this regulatory gene. Mol. Gen. Genet., 1994. 242(1): p. 40-8 [PMID:7904044] Franken P,Schrell S,Peterson PA,Saedler H,Wienand U Molecular analysis of protein domain function encoded by the myb-homologous maize genes C1, Zm 1 and Zm 38. Plant J., 1994. 6(1): p. 21-30 [PMID:7920701] Singer T,Gierl A,Peterson PA Three new dominant C1 suppressor alleles in Zea mays. Genet. Res., 1998. 71(2): p. 127-32 [PMID:9717435]