PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma

Family

C2H2

Protein Properties

Length: 497aa MW: 51737.1 Da PI: 9.1895

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thecc1EG034004t1	genome	CGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.2	1.4e-05	69	91	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Thecc1EG034004t1 69 FVCEICNKGFQRDQNLQLHRRGH 91 89*******************88 PP
2	zf-C2H2	15.8	4.1e-05	145	167	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC+ C+k + +s+ k H++t+ Thecc1EG034004t1 145 WKCERCSKKYAVQSDWKAHMKTC 167 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.76E-7	68	91	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.6E-5	68	91	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.017	69	91	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.949	69	91	IPR007087	Zinc finger, C2H2
Pfam	PF12171	7.9E-5	69	91	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE pattern	PS00028	0	71	91	IPR007087	Zinc finger, C2H2
SMART	SM00355	220	110	140	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	4.3E-5	133	166	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	2.76E-7	140	166	No hit	No description
SMART	SM00355	77	145	165	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 497 aa Download sequence Send to blast
MVELENSSPM TVSTASGEAS ASSSGNQIQG TQPTGGGPPK KKRNLPGMPD PDAEVIALSP 60 KSLLATNRFV CEICNKGFQR DQNLQLHRRG HNLPWKLRQR TSKEIRKRVY VCPEPSCVHH 120 NPARALGDLT GIKKHFCRKH GEKKWKCERC SKKYAVQSDW KAHMKTCGTR EYKCDCGTIF 180 SRRDSFITHR AFCDALAEES ARAQTLAIAN TEGNVNVSGN GNGNGKTMVG GAAATSPPPQ 240 PLTPSTASVV SPGLSIQSSE IPDNPMGLSP PTPAATSTST SNSNVFASIF APNSQPSKIP 300 APSPIFRSAA PLERTSLSLS SPLYLSNNGS SIFTGPEHDH CHYAPSPQPA MSATALLQKA 360 AQMGAAASNP SLLRGLGLAV SSTSTAGQDP NVKPESSSLT AGLGLGLPSN GSSNLTDHMM 420 DPSSLFGNKP TTLDLLGLGM GDGGASSNGL SALLTSFGGG FNVGAATTSY AAGSGSSPRE 480 TWEGAPERKP NGPAML*

Sequence ? help Back to Top

Protein Sequence Length: 497 aa Download sequence Send to blast

MVELENSSPM TVSTASGEAS ASSSGNQIQG TQPTGGGPPK KKRNLPGMPD PDAEVIALSP  60
KSLLATNRFV CEICNKGFQR DQNLQLHRRG HNLPWKLRQR TSKEIRKRVY VCPEPSCVHH  120
NPARALGDLT GIKKHFCRKH GEKKWKCERC SKKYAVQSDW KAHMKTCGTR EYKCDCGTIF  180
SRRDSFITHR AFCDALAEES ARAQTLAIAN TEGNVNVSGN GNGNGKTMVG GAAATSPPPQ  240
PLTPSTASVV SPGLSIQSSE IPDNPMGLSP PTPAATSTST SNSNVFASIF APNSQPSKIP  300
APSPIFRSAA PLERTSLSLS SPLYLSNNGS SIFTGPEHDH CHYAPSPQPA MSATALLQKA  360
AQMGAAASNP SLLRGLGLAV SSTSTAGQDP NVKPESSSLT AGLGLGLPSN GSSNLTDHMM  420
DPSSLFGNKP TTLDLLGLGM GDGGASSNGL SALLTSFGGG FNVGAATTSY AAGSGSSPRE  480
TWEGAPERKP NGPAML*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	5e-37	141	210	3	72	Zinc finger protein JACKDAW
5b3h_F	5e-37	141	210	3	72	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_007017487.1	0.0	PREDICTED: protein indeterminate-domain 2
Swissprot	Q9SCQ6	1e-147	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A061FDF7	0.0	A0A061FDF7_THECC; C2H2-like zinc finger protein
STRING	EOY14712	0.0	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM155	28	306

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G66730.1	1e-111	C2H2-like zinc finger protein

Link Out ? help Back to Top
Phytozome	Thecc1EG034004t1
Entrez Gene	18591353

Publications ? help Back to Top
Motamayor JC, et al. The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color. Genome Biol., 2013. 14(6): p. r53 [PMID:23731509] Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]