PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thecc1EG025913t1
Common NameTCM_025913
Organism
Theobroma cacao
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma
Family ERF
Protein Properties Length: 281aa    MW: 31177.7 Da    PI: 7.4092
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thecc1EG025913t1genomeCGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP2582.4e-184190255
               AP2  2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
                      ++ GVr+++ +grWvAeI+d +   ++ r +lg+f taeeAa+a+++a+  l+g
  Thecc1EG025913t1 41 KFVGVRQRP-SGRWVAEIKDTT---QKIRMWLGTFETAEEAARAYDEAACLLRG 90
                      799******.7*********32...35**********************99987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.730.106.9E-284198IPR001471AP2/ERF domain
SuperFamilySSF541713.27E-194198IPR016177DNA-binding domain
CDDcd000183.69E-324197No hitNo description
PROSITE profilePS5103219.5854198IPR001471AP2/ERF domain
PfamPF008475.5E-134190IPR001471AP2/ERF domain
SMARTSM003801.4E-3541104IPR001471AP2/ERF domain
PRINTSPR003679.6E-84253IPR001471AP2/ERF domain
PRINTSPR003679.6E-86480IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 281 aa     Download sequence    Send to blast
MEIQFQQQEQ QQQLHRKSSN IPVSKGGKFK GRNKNNGKVN KFVGVRQRPS GRWVAEIKDT  60
TQKIRMWLGT FETAEEAARA YDEAACLLRG SNTRTNFITQ VSLDSPLASR IRNLLNSKKG  120
AKEQSVLVSA PTTTTSASTN PSPSSSTSSS SCNSSRGLSN DNSSPTGMVQ DTQLFEDAYK  180
PDMSHCARGF EFASSQSDFS HTSEPGFDRF LYTQEIMNFP KNVLLPEETG SELTEFQRMK  240
VERQISASLY AMNGVQEYLE TVHDSAEALW DLPPLCSLFC *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A1e-14401071381Ethylene-responsive transcription factor ERF096
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in symbiotic nodule signaling in response to rhizobial Nod factors (NFs) (PubMed:17449807, PubMed:17827349). Binds to the GCC-box (NF-responsive box) of ENOD11 promoter. Acts as transcriptional activator of NF-responsive box-containing target gene promoters in root hairs (PubMed:17827349). Functions as a transcriptional regulator required for root infection by symbiotic rhizobia, infection thread (IT) formation and maintenance, and nodule development. Necessary for NF-induced gene expression and spontaneous nodulation activated by CCAMK. Functions downstream of CCAMK to activate nodulation gene expression (PubMed:17449807). Involved in early stages of root nodule development. Functions redundantly with ERN2. Is essential with ERN2 for the initiation of root hair infection, and nodule organogenesis and development. Required for accurate expression of the NF signaling genes ENOD11 and ENOD12 (PubMed:23077241, PubMed:27208242). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349, ECO:0000269|PubMed:23077241, ECO:0000269|PubMed:27208242}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced in roots from 1 to 21 day after inoculation with Sinorhizobium meliloti (PubMed:17449807). Induced by Nod factors in root hairs (PubMed:17827349). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007030077.20.0PREDICTED: ethylene-responsive transcription factor RAP2-11
SwissprotA2Q5W11e-113ERN1_MEDTR; Ethylene-responsive transcription factor ERN1
TrEMBLA0A061F7U70.0A0A061F7U7_THECC; AP2/ERF domain-containing transcription factor, putative
STRINGEOY105790.0(Theobroma cacao)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM16007712
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G19790.19e-23related to AP2 11
Publications ? help Back to Top
  1. Cerri MR, et al.
    Medicago truncatula ERN transcription factors: regulatory interplay with NSP1/NSP2 GRAS factors and expression dynamics throughout rhizobial infection.
    Plant Physiol., 2012. 160(4): p. 2155-72
    [PMID:23077241]
  2. Motamayor JC, et al.
    The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color.
    Genome Biol., 2013. 14(6): p. r53
    [PMID:23731509]
  3. Tang H, et al.
    An improved genome release (version Mt4.0) for the model legume Medicago truncatula.
    BMC Genomics, 2014. 15: p. 312
    [PMID:24767513]
  4. Cerri MR, et al.
    The Symbiosis-Related ERN Transcription Factors Act in Concert to Coordinate Rhizobial Host Root Infection.
    Plant Physiol., 2016. 171(2): p. 1037-54
    [PMID:27208242]