PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma

Family

bHLH

Protein Properties

Length: 220aa MW: 25034.2 Da PI: 5.7435

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thecc1EG020866t1	genome	CGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	30.2	8.2e-10	68	115	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rEr RR+r+N++f L ++l + + + +K++iL A++ + +L Thecc1EG020866t1 68 TKACRERLRRERLNERFLDLSSILEPG---RPARTDKSAILDDAIRVLTQL 115 6789********************8...789***********99998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	1.1E-13	56	132	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	13.275	64	115	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	3.5E-7	68	115	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.9E-11	70	137	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.5E-9	70	121	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 220 aa Download sequence Send to blast
MDSIEDWDFL DYSFIDENTS PDLLLPNYSD GREIELSSGN VVHQEKEFED RDCSRKRGRS 60 GSCSRPGTKA CRERLRRERL NERFLDLSSI LEPGRPARTD KSAILDDAIR VLTQLRTEAQ 120 ELKETNEKLQ EEIKSLKAEK NELREEKLVL KGNKEKIEQQ LKTMTIPPAG YLPAHPAAYH 180 PGASKMAVFP GYGLVPMWQY LPQSARDTSH DHELRPPAA*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	73	78	RLRRER

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00102	PBM	Transfer from AT4G14410	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_007035086.1	1e-162	PREDICTED: transcription factor bHLH104 isoform X1
Swissprot	Q8L467	2e-87	BH104_ARATH; Transcription factor bHLH104
TrEMBL	A0A061ENR0	1e-160	A0A061ENR0_THECC; Basic helix-loop-helix DNA-binding superfamily protein isoform 1
STRING	EOY06012	1e-161	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4026	26	53

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G14410.2	2e-65	bHLH family protein

Link Out ? help Back to Top
Phytozome	Thecc1EG020866t1
Entrez Gene	18603198

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Motamayor JC, et al. The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color. Genome Biol., 2013. 14(6): p. r53 [PMID:23731509] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Wang C,Yao X,Yu D,Liang G Fe-deficiency-induced expression of bHLH104 enhances Fe-deficiency tolerance of Arabidopsis thaliana. Planta, 2017. 246(3): p. 421-431 [PMID:28451750] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Min JH, et al. A basic helix-loop-helix 104 (bHLH104) protein functions as a transcriptional repressor for glucose and abscisic acid signaling in Arabidopsis. Plant Physiol. Biochem., 2019. 136: p. 34-42 [PMID:30639920]