 |
Plant Transcription
Factor Database
|
Transcription Factor Information
|
Basic
Information? help
Back to Top |
| TF ID |
Thecc1EG020336t1 |
| Common Name | TCM_020336 |
| Organism |
|
| Taxonomic ID |
|
| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma
|
| Family |
bHLH |
| Protein Properties |
Length: 414aa MW: 46824.5 Da PI: 5.6144 |
| Description |
bHLH family protein |
| Gene Model |
| Gene Model ID |
Type |
Source |
Coding Sequence |
| Thecc1EG020336t1 | genome | CGD | View CDS |
|
| Signature Domain? help Back to Top |
 |
| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | HLH | 38 | 2.9e-12 | 206 | 257 | 1 | 55 |
CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
HLH 1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55
+r++h ++Er+RR+++N+ + Lr+l+P + + ++ + a+i A+e++++L+
Thecc1EG020336t1 206 QRMTHIAVERNRRKQMNEHLRVLRSLMPGS---YVQRGDQASIIGGAIEFVRELE 257
79****************************...9*****************9995 PP
|
| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0010377 | Biological Process | guard cell fate commitment |
| GO:0045597 | Biological Process | positive regulation of cell differentiation |
| GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated |
| GO:0051782 | Biological Process | negative regulation of cell division |
| GO:0005634 | Cellular Component | nucleus |
| GO:0003677 | Molecular Function | DNA binding |
| GO:0016597 | Molecular Function | amino acid binding |
| GO:0046983 | Molecular Function | protein dimerization activity |
| Sequence ? help Back to Top |
| Protein Sequence Length: 414 aa
Download sequence Send
to blast |
MEKEENYSAN FTGLDYSLDH HGHDHHHHHH QDQLMKQPRI GETSGDNNGM IDYMLNNPQQ 60
QQQISSSGFC SSTPTSYDKL SFADVMQFAD FGPKLALNQT RIPEEETGID PAGYFLRFPV 120
LNDRLEDQSL MVTPSGIENV ENRATGILVE EKGNREDEEA RVSDNASVQL RFLGEDHVQN 180
KNATTEAKNK RKRPRTIKTS EEVESQRMTH IAVERNRRKQ MNEHLRVLRS LMPGSYVQRG 240
DQASIIGGAI EFVRELEQLL QCLESQKRRR LYGEASSRPM GDTSMAIQQQ QQPFFPAPMS 300
LPNDQIKLVD FDTGLREETA ENKSCLADVE VKLLGFDAMI KILSRRRPGQ LIKTIAALED 360
LQLNILHTNI TTIEQTVLYS FNVKVASEAR FSAEDIASSV QQIFTFIQAN GSM*
|
| Nucleic Localization
Signal ? help
Back to Top |
 |
| No. |
Start |
End |
Sequence |
| 1 | 206 | 217 | RMTHIAVERNRR |
| 2 | 266 | 270 | KRRRL |
| Functional Description ? help
Back to Top |
| Source |
Description |
| UniProt | Transcription activator (PubMed:17088607, PubMed:17183265, PubMed:17183267). Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata (PubMed:17088607, PubMed:17183265, PubMed:17183267). Prevents histone H3K27me3 marks and derepresses stem cell gene expression (PubMed:24654956). {ECO:0000269|PubMed:17088607, ECO:0000269|PubMed:17183265, ECO:0000269|PubMed:17183267, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24654956}. |
| Regulation -- Description ? help
Back to Top |
| Source |
Description |
| UniProt | INDUCTION: Inhibited by low relative humidity (LRH) via epigenetic CG methylation, thus leading to a reduced stomatal index. {ECO:0000269|PubMed:22442411}. |
| Publications
? help Back to Top |
- Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
Differentiation, 2010. 80(1): p. 1-8
[PMID:20219281] - Motamayor JC, et al.
The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color.
Genome Biol., 2013. 14(6): p. r53
[PMID:23731509] - Matos JL, et al.
Irreversible fate commitment in the Arabidopsis stomatal lineage requires a FAMA and RETINOBLASTOMA-RELATED module.
Elife, 2015.
[PMID:25303364] - Chen L, et al.
NRPB3, the third largest subunit of RNA polymerase II, is essential for stomatal patterning and differentiation in Arabidopsis.
Development, 2016. 143(9): p. 1600-11
[PMID:26989174] - Lee JH,Jung JH,Park CM
Light Inhibits COP1-Mediated Degradation of ICE Transcription Factors to Induce Stomatal Development in Arabidopsis.
Plant Cell, 2017. 29(11): p. 2817-2830
[PMID:29070509] - Han X, et al.
Jasmonate Negatively Regulates Stomatal Development in Arabidopsis Cotyledons.
Plant Physiol., 2018. 176(4): p. 2871-2885
[PMID:29496884] - Li X,Yang R,Chen H
The Arabidopsis thaliana Mediator subunit MED8 regulates plant immunity to Botrytis Cinerea through interacting with the basic helix-loop-helix (bHLH) transcription factor FAMA.
PLoS ONE, 2018. 13(3): p. e0193458
[PMID:29513733]
|
