PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sp_176650_ikao.t1
Common NameSOVF_176650
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Chenopodiaceae; Chenopodioideae; Anserineae; Spinacia
Family C2H2
Protein Properties Length: 225aa    MW: 25991.2 Da    PI: 5.2696
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sp_176650_ikao.t1genomeTBVRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H217.98.3e-061034123
                       EEET..TTTEEESSHHHHHHHHHHT CS
            zf-C2H2  1 ykCp..dCgksFsrksnLkrHirtH 23
                       + Cp  dCgk++ + + Lk+Hi +H
  Sp_176650_ikao.t1 10 HICPysDCGKRYAHEYKLKNHIASH 34
                       68*********************96 PP

2zf-C2H216.32.7e-057196123
                       EEET..TTTEEESSHHHHHHHHHH.T CS
            zf-C2H2  1 ykCp..dCgksFsrksnLkrHirt.H 23
                       ++Cp   C+k + + + L+ H+r+ H
  Sp_176650_ikao.t1 71 FTCPyeGCDKAYIHEYKLNLHLRReH 96
                       89**********************99 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576672.66E-6136No hitNo description
Gene3DG3DSA:3.30.160.601.1E-8136IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.4941039IPR007087Zinc finger, C2H2
SMARTSM003550.00411034IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002801235IPR007087Zinc finger, C2H2
SuperFamilySSF576674.36E-66594No hitNo description
Gene3DG3DSA:3.30.160.606.7E-96694IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.82771101IPR007087Zinc finger, C2H2
SMARTSM003550.00347196IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002807396IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 225 aa     Download sequence    Send to blast
MKTHSQENYH ICPYSDCGKR YAHEYKLKNH IASHHEKNSA EVPKYTPPVE KPVKTPKAAS  60
GTYSASSDRP FTCPYEGCDK AYIHEYKLNL HLRREHPGHY AEENAKTPQA NNVDHEMDEA  120
SDQDAYANKR SSWKSLKQSR PKPNLKLPPS KMSQRKGSGV SPAKVNIVKK PWQIKGETEY  180
DVKGETEYDE EDSEETEEDR DNVEDGRRYR ENNDDDDDEE TEDED
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021864252.11e-164zinc finger transcription factor YY1
SwissprotQ2V3L35e-70YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A0K9QI601e-165A0A0K9QI60_SPIOL; Uncharacterized protein
STRINGXP_010670021.16e-97(Beta vulgaris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.23e-61C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]