PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Sopim06g074010.0.1

Organism

Solanum pimpinellifolium

Taxonomic ID

4084

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon

Family

E2F/DP

Protein Properties

Length: 848aa MW: 93153.7 Da PI: 4.4474

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sopim06g074010.0.1	genome	CSHL	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	84.5	8.3e-27	124	189	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++ll+++++gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn i+wkg Sopim06g074010.0.1 124 RYDNSLGLLTKKFINLLKHAKDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNMIQWKG 189 689*****************************...99..**************************98 PP
2	E2F_TDP	70.2	2.5e-22	530	593	3	71
E2F_TDP 3 eksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 ++sL+ lt+kf++l+++se+g+++ln++a++L +v k+RR+YD++ VLe+++liekk+ n i+w+g Sopim06g074010.0.1 530 DNSLGFLTKKFINLIKHSEDGVLDLNKAADTL---EV--KKRRLYDVTSVLEGIGLIEKKSLNMIQWEG 593 89****************************...99..9*************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	6.7E-29	122	191	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	9.1E-35	124	189	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	5.24E-18	124	187	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	4.4E-24	126	189	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	4.04E-43	200	306	No hit	No description
SuperFamily	SSF144074	2.88E-30	202	306	No hit	No description
Pfam	PF16421	3.4E-30	205	304	IPR032198	E2F transcription factor, CC-MB domain
Gene3D	G3DSA:1.10.10.10	3.3E-24	527	595	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	7.5E-30	528	593	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	1.14E-15	529	591	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	3.7E-21	530	593	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	1.24E-38	604	710	No hit	No description
SuperFamily	SSF144074	2.88E-27	606	710	No hit	No description
Pfam	PF16421	2.1E-26	609	708	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 848 aa Download sequence Send to blast
MQPNQQRPSK RQLPFTSSKP PLGDYHRFST DPLHPSSQEL EGIAVKSTPL KRKSGTINYE 60 QGVGAQVSGC ESVYVSSPML TPISGKAGKS QKEPRASKAR SAAQATSSLG SPSGNNVTPV 120 GPCRYDNSLG LLTKKFINLL KHAKDGILDL NKAADTLEVQ KRRIYDITNV LEGIGLIEKK 180 LKNMIQWKGL DVSRPGEVDE SVTSLQAGVE NLTIEESRLD EQIRKMKERL RDLSGDENNK 240 RWLFVTEDDI KSLPCLQNDT LIAIKAPHGT SLEVPDPDEA VDYPERRYRI VFRSTMGPID 300 VYLVSKFEEK FEEINTVEEP STMPSTSGFI ENETATLPVD DGGGVGVGVL EQENQRECPD 360 AGTSQDFVSG ITKIIPDVDN EADYWLLSDA DVSITDMWTE SALNWNALDA INEDYSIADV 420 STPRAQTPPS STIEVPSGKS TGRSWQFESQ GNELHCTPLK RKSETANHEQ GVGAQIAGCG 480 NANVSSSMQT PISGKAGKSQ KAPKSSAQAT SSLGSHSGNN VTPVGPCCYD NSLGFLTKKF 540 INLIKHSEDG VLDLNKAADT LEVKKRRLYD VTSVLEGIGL IEKKSLNMIQ WEGLDVSRPG 600 DVDESVTSLQ AEVENLTIEE SILDEQIREK QERLRVLSED ENNQRWLFVT EDDIKSLPCL 660 QNYTLIAIRF LHGTSLEVPD PNEAVDYPQR RYSIVIRSTM GPIDVYLISK FEEKFKQITT 720 VEEPSTMPST SGFIEKETAA LPVDDGRGVG VAMEEQENQR ECPDAGTSQN PVSGIIKIVP 780 DFDNQEEDYL FLSDAHVSNT DMWTESVRDA LDSIYEDYSI ADVSSPHAQT PLSSTTELTS 840 ANTTEAE*

Sequence ? help Back to Top

Protein Sequence Length: 848 aa Download sequence Send to blast

MQPNQQRPSK RQLPFTSSKP PLGDYHRFST DPLHPSSQEL EGIAVKSTPL KRKSGTINYE  60
QGVGAQVSGC ESVYVSSPML TPISGKAGKS QKEPRASKAR SAAQATSSLG SPSGNNVTPV  120
GPCRYDNSLG LLTKKFINLL KHAKDGILDL NKAADTLEVQ KRRIYDITNV LEGIGLIEKK  180
LKNMIQWKGL DVSRPGEVDE SVTSLQAGVE NLTIEESRLD EQIRKMKERL RDLSGDENNK  240
RWLFVTEDDI KSLPCLQNDT LIAIKAPHGT SLEVPDPDEA VDYPERRYRI VFRSTMGPID  300
VYLVSKFEEK FEEINTVEEP STMPSTSGFI ENETATLPVD DGGGVGVGVL EQENQRECPD  360
AGTSQDFVSG ITKIIPDVDN EADYWLLSDA DVSITDMWTE SALNWNALDA INEDYSIADV  420
STPRAQTPPS STIEVPSGKS TGRSWQFESQ GNELHCTPLK RKSETANHEQ GVGAQIAGCG  480
NANVSSSMQT PISGKAGKSQ KAPKSSAQAT SSLGSHSGNN VTPVGPCCYD NSLGFLTKKF  540
INLIKHSEDG VLDLNKAADT LEVKKRRLYD VTSVLEGIGL IEKKSLNMIQ WEGLDVSRPG  600
DVDESVTSLQ AEVENLTIEE SILDEQIREK QERLRVLSED ENNQRWLFVT EDDIKSLPCL  660
QNYTLIAIRF LHGTSLEVPD PNEAVDYPQR RYSIVIRSTM GPIDVYLISK FEEKFKQITT  720
VEEPSTMPST SGFIEKETAA LPVDDGRGVG VAMEEQENQR ECPDAGTSQN PVSGIIKIVP  780
DFDNQEEDYL FLSDAHVSNT DMWTESVRDA LDSIYEDYSI ADVSSPHAQT PLSSTTELTS  840
ANTTEAE*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	1e-26	119	594	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004241343.1	0.0	transcription factor E2FB-like isoform X1
Swissprot	Q9FV71	1e-134	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A3Q7H2M1	0.0	A0A3Q7H2M1_SOLLC; Uncharacterized protein
STRING	Solyc06g074010.2.1	0.0	(Solanum lycopersicum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1077	24	84

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.2	1e-138	E2F transcription factor 1

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]