PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon

Family

MYB

Protein Properties

Length: 536aa MW: 59439.4 Da PI: 8.0888

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sopen09g005550.1	genome	spenn	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	51.9	1.8e-16	59	104	1	47
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 +g WT+eEd+ l++av + g++Wk+Ia+ ++ R++ qc +rwqk+ Sopen09g005550.1 59 KGGWTPEEDDTLKQAVSVYRGKCWKKIAEFFP-DRSEVQCLHRWQKV 104 688***************************.**********96 PP
2	Myb_DNA-binding	53.2	6.7e-17	111	157	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT eEd++++++v+++G+ W+ Ia+ + gR +kqc++rw+++l Sopen09g005550.1 111 KGPWTREEDDKIIELVAKYGPIKWSVIAKSLT-GRIGKQCRERWHNHL 157 79****************99*****9.***********97 PP
3	Myb_DNA-binding	54.4	2.9e-17	163	206	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 +++WT eE+ l+da++ +G++ W+ Ia+ ++ gRt++ +k++w++ Sopen09g005550.1 163 KDAWTLEEERALIDAHRIHGNK-WAEIAKVLP-GRTDNGIKNHWNS 206 679*****************.*****.*********96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	16.538	54	105	IPR017930	Myb domain
SuperFamily	SSF46689	1.08E-14	55	112	IPR009057	Homeodomain-like
SMART	SM00717	1.1E-14	58	107	IPR001005	SANT/Myb domain
Pfam	PF00249	3.4E-15	59	104	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	4.1E-21	61	117	IPR009057	Homeodomain-like
CDD	cd00167	1.47E-12	62	105	No hit	No description
PROSITE profile	PS51294	30.523	106	161	IPR017930	Myb domain
SuperFamily	SSF46689	1.61E-30	108	204	IPR009057	Homeodomain-like
SMART	SM00717	3.0E-17	110	159	IPR001005	SANT/Myb domain
CDD	cd00167	8.32E-15	113	157	No hit	No description
Pfam	PF13921	2.3E-17	114	174	No hit	No description
Gene3D	G3DSA:1.10.10.60	1.4E-26	118	164	IPR009057	Homeodomain-like
SMART	SM00717	2.5E-16	162	210	IPR001005	SANT/Myb domain
PROSITE profile	PS51294	22.531	162	212	IPR017930	Myb domain
CDD	cd00167	2.67E-12	165	208	No hit	No description
Gene3D	G3DSA:1.10.10.60	2.9E-23	165	212	IPR009057	Homeodomain-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 536 aa Download sequence Send to blast
MDEMKVEECC TENKQSAAAS SSSVSENSGS VTLRSPAVSS PTPASPTHRR TTGPIRRAKG 60 GWTPEEDDTL KQAVSVYRGK CWKKIAEFFP DRSEVQCLHR WQKVINPELV KGPWTREEDD 120 KIIELVAKYG PIKWSVIAKS LTGRIGKQCR ERWHNHLNPN IKKDAWTLEE ERALIDAHRI 180 HGNKWAEIAK VLPGRTDNGI KNHWNSSLKK KLDFYVATGN LPPATGTAKA EELPVWSNKT 240 SEGAEVASSG TTDTCKIENR WQVAEISASN GGPQTESTDS EVVRLESQSP EEDAIQHIKP 300 STQSENRYEG WNMDSAVGRL QVFEAPFPCE IPTCGMLCYE PPRSESCIPL DSDLLNICRA 360 QCESDASPSP SPDGFFTPPS TKGRSLCAQT PESVLRIAAR SFPNTPSILR KRKTQGELST 420 PTNKMGKSDG DLRMEKPIDA RDEIQYDSSH KSSMHNGVSS RNSFNGGLYN SQAFNASPPY 480 RLRSKRTSIF KSVEKQLRFA VNKEKHDTSN GFSGSTVNEI SHAAKDCSQD TAKKVE

Sequence ? help Back to Top

Protein Sequence Length: 536 aa Download sequence Send to blast

MDEMKVEECC TENKQSAAAS SSSVSENSGS VTLRSPAVSS PTPASPTHRR TTGPIRRAKG  60
GWTPEEDDTL KQAVSVYRGK CWKKIAEFFP DRSEVQCLHR WQKVINPELV KGPWTREEDD  120
KIIELVAKYG PIKWSVIAKS LTGRIGKQCR ERWHNHLNPN IKKDAWTLEE ERALIDAHRI  180
HGNKWAEIAK VLPGRTDNGI KNHWNSSLKK KLDFYVATGN LPPATGTAKA EELPVWSNKT  240
SEGAEVASSG TTDTCKIENR WQVAEISASN GGPQTESTDS EVVRLESQSP EEDAIQHIKP  300
STQSENRYEG WNMDSAVGRL QVFEAPFPCE IPTCGMLCYE PPRSESCIPL DSDLLNICRA  360
QCESDASPSP SPDGFFTPPS TKGRSLCAQT PESVLRIAAR SFPNTPSILR KRKTQGELST  420
PTNKMGKSDG DLRMEKPIDA RDEIQYDSSH KSSMHNGVSS RNSFNGGLYN SQAFNASPPY  480
RLRSKRTSIF KSVEKQLRFA VNKEKHDTSN GFSGSTVNEI SHAAKDCSQD TAKKVE

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h88_C	5e-69	58	212	5	159	MYB PROTO-ONCOGENE PROTEIN
1h89_C	5e-69	58	212	5	159	MYB PROTO-ONCOGENE PROTEIN
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). {ECO:0000250\|UniProtKB:Q94FL9, ECO:0000269\|PubMed:26069325}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00482	DAP	Transfer from AT5G02320	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Slightly induced by ethylene and salicylic acid (SA). {ECO:0000269\|PubMed:16463103}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975448	0.0	HG975448.1 Solanum pennellii chromosome ch09, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015086262.1	0.0	transcription factor MYB3R-3
Refseq	XP_015086263.1	0.0	transcription factor MYB3R-3
Swissprot	Q6R032	1e-143	MB3R5_ARATH; Transcription factor MYB3R-5
TrEMBL	A0A3Q7HZV4	0.0	A0A3Q7HZV4_SOLLC; Uncharacterized protein
STRING	Solyc09g010820.2.1	0.0	(Solanum lycopersicum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA5461	24	37

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G02320.2	1e-133	myb domain protein 3r-5

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325] Chen P, et al. Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage. Nat Commun, 2017. 8(1): p. 635 [PMID:28935922]