PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon

Family

C2H2

Protein Properties

Length: 499aa MW: 53957.5 Da PI: 7.9454

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sopen04g033710.1	genome	spenn	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.2	1.4e-05	49	71	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Sopen04g033710.1 49 FVCEICNKGFQRDQNLQLHRRGH 71 89*******************88 PP
2	zf-C2H2	13.7	0.00018	125	147	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC+ C+k + +s+ k H++t+ Sopen04g033710.1 125 FKCERCTKKYAVHSDWKAHMKTC 147 89*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	6.64E-7	48	71	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.6E-5	48	71	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.949	49	71	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.017	49	71	IPR015880	Zinc finger, C2H2-like
Pfam	PF12171	7.9E-5	49	71	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE pattern	PS00028	0	51	71	IPR007087	Zinc finger, C2H2
SMART	SM00355	220	90	120	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	1.3E-4	113	146	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	6.64E-7	120	146	No hit	No description
SMART	SM00355	73	125	145	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 499 aa Download sequence Send to blast
MAEIEKSAEE SSIQQNFPVK RKRNLPGNPD PEAEVIALSP RTLMATNRFV CEICNKGFQR 60 DQNLQLHRRG HNLPWKLRQR TSNEVKKRVY VCPESTCVHH DPSRALGDLT GIKKHFCRKH 120 GEKKFKCERC TKKYAVHSDW KAHMKTCGTR EYRCDCGTLF SRRDSFITHR AFCDALAQES 180 ARSHQPLMED TNAEGDLKVD ESINKTVSSS SSPPPQPLTP STGVLSPVLS IQSSELPVEY 240 QNQGGVQIQQ AQGTTTPVST TPAITISTAA ANGPSSSKVF ASVFPSSSSA QHVNSSYSDI 300 LRAIETEQVM AVEPISLSLS SSLYLSNNGP SLFQEHTGGH GHGQHYGSAT MQPALSATAL 360 LQKAAQMGST TSNNSFLRGL GLGMSPSTST PEENSLARRT NALGHVKLES NINAEVPGLG 420 IQLHGHSGFT DLMMGPSISH QTSMMFGSKP PTLDFLGLGN GASGTPSSGF SAFLSSMEDG 480 FGVVAEPWDD PSDRKPAML

Sequence ? help Back to Top

Protein Sequence Length: 499 aa Download sequence Send to blast

MAEIEKSAEE SSIQQNFPVK RKRNLPGNPD PEAEVIALSP RTLMATNRFV CEICNKGFQR  60
DQNLQLHRRG HNLPWKLRQR TSNEVKKRVY VCPESTCVHH DPSRALGDLT GIKKHFCRKH  120
GEKKFKCERC TKKYAVHSDW KAHMKTCGTR EYRCDCGTLF SRRDSFITHR AFCDALAQES  180
ARSHQPLMED TNAEGDLKVD ESINKTVSSS SSPPPQPLTP STGVLSPVLS IQSSELPVEY  240
QNQGGVQIQQ AQGTTTPVST TPAITISTAA ANGPSSSKVF ASVFPSSSSA QHVNSSYSDI  300
LRAIETEQVM AVEPISLSLS SSLYLSNNGP SLFQEHTGGH GHGQHYGSAT MQPALSATAL  360
LQKAAQMGST TSNNSFLRGL GLGMSPSTST PEENSLARRT NALGHVKLES NINAEVPGLG  420
IQLHGHSGFT DLMMGPSISH QTSMMFGSKP PTLDFLGLGN GASGTPSSGF SAFLSSMEDG  480
FGVVAEPWDD PSDRKPAML

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	1e-32	121	182	3	64	Zinc finger protein JACKDAW
5b3h_F	1e-32	121	182	3	64	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT013478	0.0	BT013478.1 Lycopersicon esculentum clone 132154R, mRNA sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015071972.1	0.0	zinc finger protein GAI-ASSOCIATED FACTOR 1-like
Swissprot	Q9SCQ6	1e-132	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A3Q7G9T0	0.0	A0A3Q7G9T0_SOLLC; Uncharacterized protein
STRING	Solyc04g080130.2.1	0.0	(Solanum lycopersicum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA103	24	350

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	1e-111	indeterminate(ID)-domain 2

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]