PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon

Family

MYB_related

Protein Properties

Length: 89aa MW: 9801.92 Da PI: 9.8658

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Solyc10g052470.1.1	genome	ITAG	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	30.1	1.1e-09	12	56	2	44
SSS-HHHHHHHHHHHHHTTTT...-HHHHHHHHTTTS-HHHHHHHH CS Myb_DNA-binding 2 grWTteEdellvdavkqlGgg...tWktIartmgkgRtlkqcksrw 44 g+WT+ + + +a + + ++ +W+ +a+ +g g+t++++k ++ Solyc10g052470.1.1 12 GSWTAKQNKAFEKALAVYDKEtrdRWSNVAKAVG-GKTAEEVKRHY 56 89****************9*********.********9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	9.7E-6	7	61	IPR009057	Homeodomain-like
PROSITE profile	PS51293	9.084	9	64	IPR017884	SANT domain
SMART	SM00717	1.3E-8	10	62	IPR001005	SANT/Myb domain
Pfam	PF00249	2.4E-7	12	56	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	4.34E-13	12	68	IPR009057	Homeodomain-like
CDD	cd00167	3.79E-7	14	60	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 89 aa Download sequence Send to blast
MSSMSSQHGS SGSWTAKQNK AFEKALAVYD KETRDRWSNV AKAVGGKTAE EVKRHYEILL 60 RDVFFIDNGM VPFPKYKTTG GSHNSTSD*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2cjj_A	4e-35	4	82	1	79	RADIALIS
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Early expressed at stage two (plastochrons 7 and 8), when the floral meristem comprised a loaf-shaped bulge of cells. Expression was in the dorsal region of the floral meristem. At stage four, when sepal primordia had emerged around the meristem dome, expression could be seen in the dorsal sepal primordium. At stage five, expressed in emerging dorsal primordia of whorls two and three. In older flower buds (stages seven and eight), expression was found mainly in the dorsal petals and staminode. {ECO:0000269\|PubMed:15790677}.
Uniprot	TISSUE SPECIFICITY: Specifically expressed in the dorsal region of developing flowers. {ECO:0000269\|PubMed:15790677}.

Functional Description ? help Back to Top
Source	Description
UniProt	Involved in the dorsovental asymmetry of flowers. Promotes dorsal identity. {ECO:0000269\|PubMed:15790677}.

Function -- GeneRIF ? help Back to Top
FSM1/FSB1/MYBI complex controls tomato cell expansion, while revealing a mechanism by which competing MYB-MYB interactions could participate in the control of gene expression. [PMID: 21707804] There was strong genotype-dependent suppression of tomato morphogenesis-regulating transcription factor SANT/HTH-Myb (SlMyb) due to viroid pathogenesis. [PMID: 26118459]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Solyc10g052470.1.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by both CYC and DICH. {ECO:0000269\|PubMed:15790677, ECO:0000269\|PubMed:16236768}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AJ277944	1e-149	Lycopersicon esculentum mRNA for SANT/MYB domain protein (fsm1 gene)
GenBank	AJ583670	1e-149	Lycopersicon esculentum fsm1 gene for SANT/MYB protein, exons 1-2

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001233849.1	1e-60	SANT/MYB domain protein
Refseq	XP_015055159.1	1e-60	protein RADIALIS-like 1
Swissprot	Q58FS3	7e-35	RAD_ANTMA; Transcription factor RADIALIS
TrEMBL	Q9LEG4	2e-59	Q9LEG4_SOLLC; SANT/MYB domain protein
STRING	Solyc10g052470.1.1	4e-60	(Solanum lycopersicum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA202	24	231
Representative plant	OGRP347	12	98

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G39250.1	2e-35	RAD-like 1

Link Out ? help Back to Top
Phytozome	Solyc10g052470.1.1
Entrez Gene	543759

Publications ? help Back to Top
Barg R, et al. The tomato early fruit specific gene Lefsm1 defines a novel class of plant-specific SANT/MYB domain proteins. Planta, 2005. 221(2): p. 197-211 [PMID:15599593] Corley SB,Carpenter R,Copsey L,Coen E Floral asymmetry involves an interplay between TCP and MYB transcription factors in Antirrhinum. Proc. Natl. Acad. Sci. U.S.A., 2005. 102(14): p. 5068-73 [PMID:15790677] Wang Y,van der Hoeven RS,Nielsen R,Mueller LA,Tanksley SD Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments. Theor. Appl. Genet., 2005. 112(1): p. 72-84 [PMID:16208505] Costa MM,Fox S,Hanna AI,Baxter C,Coen E Evolution of regulatory interactions controlling floral asymmetry. Development, 2005. 132(22): p. 5093-101 [PMID:16236768] Stevenson CE, et al. Crystallization and preliminary X-ray analysis of the RAD protein from Antirrhinum majus. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 2005. 61(Pt 10): p. 885-8 [PMID:16511186] Stevenson CE, et al. Crystal structure of the MYB domain of the RAD transcription factor from Antirrhinum majus. Proteins, 2006. 65(4): p. 1041-5 [PMID:17044043] Machemer K, et al. Interplay of MYB factors in differential cell expansion, and consequences for tomato fruit development. Plant J., 2011. 68(2): p. 337-50 [PMID:21707804] Matoušek J, et al. Expression of SANT/HTH Myb mRNA, a plant morphogenesis-regulating transcription factor, changes due to viroid infection. J. Plant Physiol., 2015. 183: p. 85-94 [PMID:26118459]