PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon

Family

Nin-like

Protein Properties

Length: 1612aa MW: 180949 Da PI: 6.5764

Description

Nin-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Solyc08g082750.2.1	genome	ITAG	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	RWP-RK	91.7	5.6e-29	578	629	1	52
RWP-RK 1 aekeisledlskyFslpikdAAkeLgvclTvLKriCRqyGIkRWPhRkiksl 52 aek+isle+l++yF++++kdAAk+Lgvc+T++KriCRq+GI+RWP+Rki+++ Solyc08g082750.2.1 578 AEKTISLEVLQQYFAGSLKDAAKSLGVCPTTMKRICRQHGISRWPSRKINKV 629 589***********************************************97 PP
2	RWP-RK	54.5	2.2e-17	1438	1485	3	50
RWP-RK 3 keisledlskyFslpikdAAkeLgvclTvLKriCRqyGIkRWPhRkik 50 ++++ +dl+++F++++ dAAk+L+++ ++LKr CR+yGI+RWP k k Solyc08g082750.2.1 1438 DSVNYDDLKQHFDKNLSDAAKSLQISRSTLKRLCRKYGIRRWPLSKRK 1485 678899*************************************86654 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51519	17.655	566	649	IPR003035	RWP-RK domain
Pfam	PF02042	5.9E-26	581	629	IPR003035	RWP-RK domain
SuperFamily	SSF54277	1.18E-22	882	969	No hit	No description
SMART	SM00666	1.8E-22	883	965	IPR000270	PB1 domain
PROSITE profile	PS51745	23.655	883	965	IPR000270	PB1 domain
Gene3D	G3DSA:3.10.20.240	1.9E-25	883	964	No hit	No description
CDD	cd06407	6.89E-36	884	964	No hit	No description
Pfam	PF00564	1.2E-17	884	964	IPR000270	PB1 domain
PROSITE profile	PS51519	14.618	1424	1509	IPR003035	RWP-RK domain
Pfam	PF02042	4.9E-17	1440	1486	IPR003035	RWP-RK domain
Gene3D	G3DSA:1.10.10.60	8.0E-6	1449	1476	IPR009057	Homeodomain-like
SuperFamily	SSF54277	4.21E-17	1517	1602	No hit	No description
Gene3D	G3DSA:3.10.20.240	1.1E-16	1519	1602	No hit	No description
SMART	SM00666	1.0E-11	1521	1603	IPR000270	PB1 domain
PROSITE profile	PS51745	18.625	1521	1603	IPR000270	PB1 domain
Pfam	PF00564	3.4E-13	1522	1601	IPR000270	PB1 domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009414	Biological Process	response to water deprivation
GO:0010118	Biological Process	stomatal movement
GO:0010167	Biological Process	response to nitrate
GO:0042128	Biological Process	nitrate assimilation
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 1612 aa Download sequence Send to blast
MSEPEEEMNF IFRSKPKDFV HPPPATAAAI FAAAASASNP MSPFLVSAAS EQPCSPLWAF 60 SDENEDKPNG NALSTGSLRL SNYPRFVTYA NEHEAAPETV SVTDDKKRIP PPIKGLAPLD 120 YLDSSCIIKE RMTQALRYFK ESTGERVLAQ VWAPVKNGGR YVLTTSGQPF VLDPDCNGLH 180 QYRMVSLMYM FSVDGETDGV LGLPGRVYRK KLPEWTPNVQ YYSSKEFPRL NHALDYNVRG 240 TLALPVFEPS GQSCVGVLEL IMTSQKINYA PEVDKVCKAL EAVNLKSSEI LDYPNHQICN 300 EGRQNALVEI LEILTAVCET YKLPLAQTWV PCRHRSVLAD GGGFKKSCSS FDGSCMGQVC 360 MSTTDVAFYV VDAHMWGFRE ACAEHHLQKG QGVAGRAYAS QKSCFCEDIG KFCKTEYPLV 420 HYARLFGLSR CFAICLRSTH TGNDDYILEF FLPPNDGDYT DQLALLNSLL LTMKQHFRSL 480 RVASGEELEH DWGSVEIIKA STEEKLGSRF DSVPTTKSLP QSASVANGRR HPDLMEEQHS 540 TVAKGAEGVN VTAEAHNHAS VPQNKQTGKK SERKRGKAEK TISLEVLQQY FAGSLKDAAK 600 SLGVCPTTMK RICRQHGISR WPSRKINKVN RSLSKLKRVI ESVQGADGTF SLTSLAPNSL 660 PVAVGSISWP AGINGSPCKA SEYQEEKNEF SNHGTPGSHE EAEPTDQMLG SRIIGNEELS 720 PKLNGFVREG SHRSRTGSFS REESTGTPTS HGSCQGSPSP ANESSPQNEL LNSPTQESVM 780 KVEGSLEPAR QTTGELNLST AFLMPGLFIP EHTHQQFRGM LVEDAGSSHD LRNLCPAGET 840 MFDERVPEYS WTNPPCSNGI ATNQVPLPVE KMPQFSSRPE VTSVTIKATY REDIIRFRLC 900 LNSGIYKLKE EVSKRLKLEM GTFDIKYLDD DHEWVLIACD ADLQECIDIS SSSGSNVVRL 960 LVHDIMPNLG SSCESSGVKE KIKLALQRIE TSQVILLQFW GLENIEGRKF LSTSGQPFGL 1020 RYLYKGLCWY RKHCQGYKYS VDKGENHEQG MEKTHLFGPP TRVFQQKLPE SSTHVGYYTN 1080 EEFPMRDHVL QCGVRTYLAL PVFEPVDKNC IGVIELVTVW KGGYLTCEVE RVLNPLEAVD 1140 LKCPKIFLNK DRKVQAEKYN EGEEFKRMLK IVRETHKLPF IRVWIPCVNL EMDHNGMYVG 1200 CTELAMSASN EVYFVADEEM DANDHVYDDY YYDDMLCFRD ISKLQPLQKD QGVVGKAFSS 1260 GKLCYCTNIT EFSIIEYPLV HYARWCGLTT SFAICLKSRD DAYILELFLP PDNGDPNMLL 1320 GSILTTMGQH FQNFKFASGQ ELGNDSSVQV VKASSDKNVD YFHIYQTRDS SFMPEVLHVE 1380 DSRNQLMEGN ENHMEKKEDR KQSMVQSNVL SIDSHVISEK QCVSVSHLQK ESRTRTKDSV 1440 NYDDLKQHFD KNLSDAAKSL QISRSTLKRL CRKYGIRRWP LSKRKKSSES DQQTLTKVSK 1500 KNKSIGSETT TQKDHESCSS SFTVKATFGD DMMKFKLYTF SRKDDLDNEV SKRLKLPIGR 1560 FRINYMDEDN DWIWIACDDD LSDCFNNAQS LGNNTIKMLV LPAAINHHFE L*

Sequence ? help Back to Top

Protein Sequence Length: 1612 aa Download sequence Send to blast

MSEPEEEMNF IFRSKPKDFV HPPPATAAAI FAAAASASNP MSPFLVSAAS EQPCSPLWAF  60
SDENEDKPNG NALSTGSLRL SNYPRFVTYA NEHEAAPETV SVTDDKKRIP PPIKGLAPLD  120
YLDSSCIIKE RMTQALRYFK ESTGERVLAQ VWAPVKNGGR YVLTTSGQPF VLDPDCNGLH  180
QYRMVSLMYM FSVDGETDGV LGLPGRVYRK KLPEWTPNVQ YYSSKEFPRL NHALDYNVRG  240
TLALPVFEPS GQSCVGVLEL IMTSQKINYA PEVDKVCKAL EAVNLKSSEI LDYPNHQICN  300
EGRQNALVEI LEILTAVCET YKLPLAQTWV PCRHRSVLAD GGGFKKSCSS FDGSCMGQVC  360
MSTTDVAFYV VDAHMWGFRE ACAEHHLQKG QGVAGRAYAS QKSCFCEDIG KFCKTEYPLV  420
HYARLFGLSR CFAICLRSTH TGNDDYILEF FLPPNDGDYT DQLALLNSLL LTMKQHFRSL  480
RVASGEELEH DWGSVEIIKA STEEKLGSRF DSVPTTKSLP QSASVANGRR HPDLMEEQHS  540
TVAKGAEGVN VTAEAHNHAS VPQNKQTGKK SERKRGKAEK TISLEVLQQY FAGSLKDAAK  600
SLGVCPTTMK RICRQHGISR WPSRKINKVN RSLSKLKRVI ESVQGADGTF SLTSLAPNSL  660
PVAVGSISWP AGINGSPCKA SEYQEEKNEF SNHGTPGSHE EAEPTDQMLG SRIIGNEELS  720
PKLNGFVREG SHRSRTGSFS REESTGTPTS HGSCQGSPSP ANESSPQNEL LNSPTQESVM  780
KVEGSLEPAR QTTGELNLST AFLMPGLFIP EHTHQQFRGM LVEDAGSSHD LRNLCPAGET  840
MFDERVPEYS WTNPPCSNGI ATNQVPLPVE KMPQFSSRPE VTSVTIKATY REDIIRFRLC  900
LNSGIYKLKE EVSKRLKLEM GTFDIKYLDD DHEWVLIACD ADLQECIDIS SSSGSNVVRL  960
LVHDIMPNLG SSCESSGVKE KIKLALQRIE TSQVILLQFW GLENIEGRKF LSTSGQPFGL  1020
RYLYKGLCWY RKHCQGYKYS VDKGENHEQG MEKTHLFGPP TRVFQQKLPE SSTHVGYYTN  1080
EEFPMRDHVL QCGVRTYLAL PVFEPVDKNC IGVIELVTVW KGGYLTCEVE RVLNPLEAVD  1140
LKCPKIFLNK DRKVQAEKYN EGEEFKRMLK IVRETHKLPF IRVWIPCVNL EMDHNGMYVG  1200
CTELAMSASN EVYFVADEEM DANDHVYDDY YYDDMLCFRD ISKLQPLQKD QGVVGKAFSS  1260
GKLCYCTNIT EFSIIEYPLV HYARWCGLTT SFAICLKSRD DAYILELFLP PDNGDPNMLL  1320
GSILTTMGQH FQNFKFASGQ ELGNDSSVQV VKASSDKNVD YFHIYQTRDS SFMPEVLHVE  1380
DSRNQLMEGN ENHMEKKEDR KQSMVQSNVL SIDSHVISEK QCVSVSHLQK ESRTRTKDSV  1440
NYDDLKQHFD KNLSDAAKSL QISRSTLKRL CRKYGIRRWP LSKRKKSSES DQQTLTKVSK  1500
KNKSIGSETT TQKDHESCSS SFTVKATFGD DMMKFKLYTF SRKDDLDNEV SKRLKLPIGR  1560
FRINYMDEDN DWIWIACDDD LSDCFNNAQS LGNNTIKMLV LPAAINHHFE L*

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Les.22558	0.0	flower\| leaf

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers and siliques. Detected in root hairs, emerging secondary roots, vascular tissues, leaf parenchyma cells and stomata. {ECO:0000269\|PubMed:18826430}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in regulation of nitrate assimilation and in transduction of the nitrate signal. {ECO:0000269\|PubMed:18826430}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00449	DAP	Transfer from AT4G24020	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Solyc08g082750.2.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by the N source or by nitrate. {ECO:0000269\|PubMed:18826430}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AP009397	0.0	Solanum lycopersicum genomic DNA, chromosome 8, complete sequence, clone: C08SLm0010D08

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004245486.1	0.0	protein NLP7-like
Swissprot	Q84TH9	0.0	NLP7_ARATH; Protein NLP7
TrEMBL	A0A3Q7HUP0	0.0	A0A3Q7HUP0_SOLLC; Uncharacterized protein
STRING	Solyc08g082750.2.1	0.0	(Solanum lycopersicum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA5223	22	39
Representative plant	OGRP299	16	97

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G24020.1	0.0	NIN like protein 7

Link Out ? help Back to Top
Phytozome	Solyc08g082750.2.1

Publications ? help Back to Top
Wang Y,van der Hoeven RS,Nielsen R,Mueller LA,Tanksley SD Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments. Theor. Appl. Genet., 2005. 112(1): p. 72-84 [PMID:16208505] Xu N, et al. The Arabidopsis NRG2 Protein Mediates Nitrate Signaling and Interacts with and Regulates Key Nitrate Regulators. Plant Cell, 2016. 28(2): p. 485-504 [PMID:26744214] Karve R,Suárez-Román F,Iyer-Pascuzzi AS The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release. Plant Physiol., 2016. 171(3): p. 2101-11 [PMID:27221617] Yu LH, et al. Overexpression of Arabidopsis NLP7 improves plant growth under both nitrogen-limiting and -sufficient conditions by enhancing nitrogen and carbon assimilation. Sci Rep, 2016. 6: p. 27795 [PMID:27293103] Menz J,Li Z,Schulze WX,Ludewig U Early nitrogen-deprivation responses in Arabidopsis roots reveal distinct differences on transcriptome and (phospho-) proteome levels between nitrate and ammonium nutrition. Plant J., 2016. 88(5): p. 717-734 [PMID:27419465] Yan D, et al. NIN-like protein 8 is a master regulator of nitrate-promoted seed germination in Arabidopsis. Nat Commun, 2016. 7: p. 13179 [PMID:27731416] Guan P, et al. Interacting TCP and NLP transcription factors control plant responses to nitrate availability. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(9): p. 2419-2424 [PMID:28202720] Liu KH, et al. Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks. Nature, 2017. 545(7654): p. 311-316 [PMID:28489820] Li Z, et al. The Arabidopsis CPSF30-L gene plays an essential role in nitrate signaling and regulates the nitrate transceptor gene NRT1.1. New Phytol., 2017. 216(4): p. 1205-1222 [PMID:28850721] Cao H, et al. Overexpression of the Maize ZmNLP6 and ZmNLP8 Can Complement the Arabidopsis Nitrate Regulatory Mutant nlp7 by Restoring Nitrate Signaling and Assimilation. Front Plant Sci, 2017. 8: p. 1703 [PMID:29051766] Konishi N,Okubo T,Yamaya T,Hayakawa T,Minamisawa K Nitrate Supply-Dependent Shifts in Communities of Root-Associated Bacteria in Arabidopsis. Microbes Environ., 2017. 32(4): p. 314-323 [PMID:29187692] Karve RA,Iyer-Pascuzzi AS Further insights into the role of NIN-LIKE PROTEIN 7 (NLP7) in root cap cell release. Plant Signal Behav, 2018. 13(1): p. e1414122 [PMID:29215953] Zhao L, et al. The Arabidopsis NLP7 gene regulates nitrate signaling via NRT1.1-dependent pathway in the presence of ammonium. Sci Rep, 2018. 8(1): p. 1487 [PMID:29367694]