PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Solyc08g005050.2.1
Organism
Solanum lycopersicum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon
Family bHLH
Protein Properties Length: 465aa    MW: 51491.7 Da    PI: 6.7949
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Solyc08g005050.2.1genomeITAGView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH22.22.5e-07331358434
                         HHHHHHHHHHHHHHHHHHHHHCTSCCC...T CS
                 HLH   4 ahnerErrRRdriNsafeeLrellPkaskap 34 
                         +h e+Er+RR+++N++f eLr+ +  +   +
  Solyc08g005050.2.1 331 NHVEAERQRREKLNQRFYELRSQIECL---R 358
                         799*******************99886...3 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.5E-4460222IPR025610Transcription factor MYC/MYB N-terminal
SuperFamilySSF474597.12E-7320364IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS508889.375327385IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.8E-7330360IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.12E-5330359No hitNo description
PfamPF000101.0E-4331358IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 465 aa     Download sequence    Send to blast
MTDYRLWSNT NTTNTCDDTM MMDSFLSSDP SSFWPASTPN RPTPVNGVGE TMPFFNQESL  60
QQRLQALIDG ARESWAYAIF WQSSVVDFAS QTVLGWGDGY YKGEEDKNKR RGSSSSAANF  120
VAEQEHRKKV LRELNSLISG VQASAGNGTD DAVDEEVTDT EWFFLISMTQ SFVNGNGLPG  180
LAMYSSSPIW VTGTEKLAAS QCERARQAQG FGLQTIVCIP SPESREILNF GDSSKRFSGQ  240
SQLGPGPGLM EENKNKNKNK KRSLGSRGNN EEGMLSFVSG VILPTSTMGK SGDSDHSDLE  300
ASVVKEAVVE PEKKPRKRGR KPANGREEPL NHVEAERQRR EKLNQRFYEL RSQIECLRKE  360
LTNKGSSNYS ASPPLNQDVK IVDMDIDVKV IGWDAMIRIQ CSKKNHPAAR LMAALKDLDL  420
DVHHASVSVV NDLMIQQATV KMGSRLYAQE QLRIALTSKI AESR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4rqw_A6e-54532212165Transcription factor MYC3
4rqw_B6e-54532212165Transcription factor MYC3
4rru_A3e-535522143204Transcription factor MYC3
4rs9_A6e-54532212165Transcription factor MYC3
4ywc_A3e-535522143204Transcription factor MYC3
4ywc_B3e-535522143204Transcription factor MYC3
4yz6_A6e-54532212165Transcription factor MYC3
5t0f_A7e-54532212165Transcription factor MYC3
5t0q_A7e-54532212165Transcription factor MYC3
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1312320KKPRKRGRK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Les.79180.0floral bud| fruit| leaf| root| stem| trichome
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Highly expressed in trichomes and at lower levels in leaves and flowers (PubMed:24884371). Expressed at low levels in roots, stems, leaves, flowers and fruits (PubMed:15231736). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:24884371}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds to the G-box motif (5'-AACGTG-3') found in a number of promoters of jasmonate-induced genes (PubMed:15231736). Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371, PubMed:30518626). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). Acts synergistically with EOT1 in the transactivation of TPS5 (PubMed:24884371). Involved in type VI glandular trichome development (PubMed:30518626). Involved in the activation of terpene synthases required for volatile mono- and sesquiterpenes synthesis by the glandular cells of type VI trichomes (PubMed:30518626). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:24884371, ECO:0000269|PubMed:30518626}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapSolyc08g005050.2.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by methyl jasmonate and wounding. {ECO:0000269|PubMed:15231736}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015085548.11e-159transcription factor MYC4-like
SwissprotA0A060KY901e-155MYC1_SOLLC; Transcription factor MYC1
TrEMBLA0A1R3I3Z10.0A0A1R3I3Z1_COCAP; Uncharacterized protein
STRINGSolyc08g005050.2.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA1974833
Representative plantOGRP37331224
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G32640.13e-55bHLH family protein
Publications ? help Back to Top
  1. Wang Y,van der Hoeven RS,Nielsen R,Mueller LA,Tanksley SD
    Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments.
    Theor. Appl. Genet., 2005. 112(1): p. 72-84
    [PMID:16208505]
  2. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  3. Spyropoulou EA,Haring MA,Schuurink RC
    RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters.
    BMC Genomics, 2014. 15: p. 402
    [PMID:24884371]
  4. Xu J, et al.
    SlMYC1 Regulates Type VI Glandular Trichome Formation and Terpene Biosynthesis in Tomato Glandular Cells.
    Plant Cell, 2018. 30(12): p. 2988-3005
    [PMID:30518626]