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Plant Transcription
Factor Database
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Transcription Factor Information
Basic
Information? help
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TF ID |
Solyc03g113760.2.1 |
Common Name | LOC101259523 |
Organism |
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Taxonomic ID |
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Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon
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Family |
E2F/DP |
Protein Properties |
Length: 386aa MW: 43270 Da PI: 9.0608 |
Description |
E2F/DP family protein |
Gene Model |
Gene Model ID |
Type |
Source |
Coding Sequence |
Solyc03g113760.2.1 | genome | ITAG | View CDS |
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Signature Domain? help Back to Top |
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No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
1 | E2F_TDP | 74.1 | 1.4e-23 | 17 | 82 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
rk+ksL+ll+++fl+l+ ++ +++ l+++a++L v +rRRiYDi+NVLe+++++++k+kn+++wkg
Solyc03g113760.2.1 17 RKQKSLGLLCSNFLSLYDRQGVETIGLDDAARRL---GV--ERRRIYDIVNVLESIGVLARKAKNRYSWKG 82
79*****************999************...**..****************************98 PP
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2 | E2F_TDP | 74.9 | 8.3e-24 | 152 | 232 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71
r+eksL+lltq+f+kl+ +++ ++++l+e+ak L+ + +++k+RR+YDi+NVL++++ iek ++k+++rw g
Solyc03g113760.2.1 152 RREKSLGLLTQNFVKLFLCTNVDMICLDEAAKILLGDgrppaMTRTKVRRLYDIANVLSSMKYIEKthhpeTRKPAFRWLG 232
689**************************************99999*********************99999*******87 PP
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Gene Ontology ? help Back to Top |
GO Term |
GO Category |
GO Description |
GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
GO:0032876 | Biological Process | negative regulation of DNA endoreduplication |
GO:0005634 | Cellular Component | nucleus |
GO:0005667 | Cellular Component | transcription factor complex |
GO:0003677 | Molecular Function | DNA binding |
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
Protein Sequence Length: 386 aa
Download sequence Send
to blast |
MALASDPSKE SRSTYCRKQK SLGLLCSNFL SLYDRQGVET IGLDDAARRL GVERRRIYDI 60 VNVLESIGVL ARKAKNRYSW KGLEAIPRTL EQLKEEGLKE NVSGFDGSSS AKGSDDDDDD 120 DRDSNLITSS QTDKLSSNSG VNSAAPVKSE NRREKSLGLL TQNFVKLFLC TNVDMICLDE 180 AAKILLGDGR PPAMTRTKVR RLYDIANVLS SMKYIEKTHH PETRKPAFRW LGLGGRSEYK 240 SVDAFCAIES KKRVFGTELT NTTIKRNRVA LPMDGISDEA TRKQLLTEVK CENLENAFHI 300 PKQEPGLTAS KKSYHFGPFA PPTVPQAEVS EADRMKRVHD WESLASSYRP QYHNQALKDL 360 FAHYVEAWKS WYLEVAGKNP IQLIS*
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Expression --
Description ? help
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Source |
Description |
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected during early S phase. Expressed at both the G1/S and S/G2 transitions, with a peak during G2. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:18787127}. |
Uniprot | TISSUE SPECIFICITY: Expressed exclusively in mitotically dividing cells. Highly expressed in young leaves and mature flowers. Lower expression in young stalk and in young and mature flowers. {ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366}. |
Functional Description ? help
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Source |
Description |
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Publications
? help Back to Top |
- Wang Y,van der Hoeven RS,Nielsen R,Mueller LA,Tanksley SD
Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments. Theor. Appl. Genet., 2005. 112(1): p. 72-84 [PMID:16208505] - Chandran D, et al.
Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid. Cell Host Microbe, 2014. 15(4): p. 506-13 [PMID:24721578] - Wang Z, et al.
Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis. PLoS ONE, 2016. 11(8): p. e0160684 [PMID:27505251] - Heyman J,Polyn S,Eekhout T,De Veylder L
Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1. Plant Physiol., 2017. 175(1): p. 303-313 [PMID:28698355]
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