PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Saccharinae; Saccharum; Saccharum officinarum complex

Family

C2H2

Protein Properties

Length: 182aa MW: 19133.4 Da PI: 8.9205

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-157a-Saccharum_officinarum-130608	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	13.2	0.00027	81	103	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C Cgk F + L H ++H Sof016729 81 FRCAVCGKAFASYQALGGHKSSH 103 89**********99999999888 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF13912	2.1E-12	80	105	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.11	81	103	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	7.65E-9	81	103	No hit	No description
PROSITE profile	PS50157	10.679	81	108	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	83	103	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	7.65E-9	137	164	No hit	No description
Pfam	PF13912	2.5E-6	142	164	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.32	142	164	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	9.993	142	169	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	144	164	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 182 aa Download sequence Send to blast
MAAGFEAIPD PTALSLALPT PAPGPGLKLN KEDYLAICLA ALAGTRKFGL GRERDQEQHQ 60 HQPTNKWCPP THAPAQQELR FRCAVCGKAF ASYQALGGHK SSHRKPPTPE QYAAAAAQPQ 120 AVSTADSEET TSSSGGTAGG PHRCTICRRG FATGPALGGH QRCHFWDRAS SGSVSLSGFR 180 TG

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Sof.16294	1e-111	root

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in abscisic acid (ABA) signaling. Required for the regulation of the cross-talk between NADPH oxidase, hydrogen peroxide and MAP kinase in ABA signaling. Regulates the expression of the NADPH oxidase genes RBOHB and RBOHE, and the MAPK genes MPK1, MPK4, MPK5, MPK7 and MPK14. Regulates ABA-induced hydrogen peroxide production and antioxidant defense. Required for tolerance to water stress and oxidative stress. {ECO:0000269\|PubMed:25071223}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by abscisic acid (ABA) and hydrogen peroxide. {ECO:0000269\|PubMed:25071223}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002465091.2	3e-64	uncharacterized protein LOC8063219
Refseq	XP_025797129.1	4e-68	zinc finger protein 36-like
Swissprot	Q75KE5	5e-56	ZFP36_ORYSJ; Zinc finger protein 36
TrEMBL	C5WVL9	8e-67	C5WVL9_SORBI; Uncharacterized protein
STRING	Sb01g031900.1	1e-67	(Sorghum bicolor)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G19580.2	6e-20	zinc-finger protein 2

Publications ? help Back to Top
Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764] Yilmaz A, et al. GRASSIUS: a platform for comparative regulatory genomics across the grasses. Plant Physiol., 2009. 149(1): p. 171-80 [PMID:18987217] Zhang H, et al. A novel rice C2H2-type zinc finger protein, ZFP36, is a key player involved in abscisic acid-induced antioxidant defence and oxidative stress tolerance in rice. J. Exp. Bot., 2014. 65(20): p. 5795-809 [PMID:25071223] Li W, et al. A Natural Allele of a Transcription Factor in Rice Confers Broad-Spectrum Blast Resistance. Cell, 2017. 170(1): p. 114-126.e15 [PMID:28666113]