PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Saccharinae; Saccharum; Saccharum officinarum complex

Family

C2H2

Protein Properties

Length: 199aa MW: 20669.2 Da PI: 8.3029

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Sof#S17296021	PU_ref	Unigene	View CDS
PUT-157a-Saccharum_officinarum-88218	PU_unref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	13	0.0003	72	94	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C Cgk F + L H ++H Sof004703 72 FRCAVCGKAFASYQALGGHKSSH 94 89**********99999999888 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF13912	2.3E-12	71	96	IPR007087	Zinc finger, C2H2
PROSITE profile	PS50157	10.679	72	99	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.11	72	94	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	3.54E-8	72	94	No hit	No description
PROSITE pattern	PS00028	0	74	94	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	3.54E-8	129	156	No hit	No description
SMART	SM00355	0.91	134	156	IPR015880	Zinc finger, C2H2-like
Pfam	PF13912	5.1E-10	134	157	IPR007087	Zinc finger, C2H2
PROSITE profile	PS50157	8.995	134	156	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	136	156	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 199 aa Download sequence Send to blast
MEDLVIDPTA LSLALPAPAA PALSKEDYLA ICLAALAGTR KFGLGREREQ HQHHPTDKWC 60 PTHAPAQQEL RFRCAVCGKA FASYQALGGH KSSHRKPPTP EQYAAALATA AQTASGSDLN 120 ETASSGSAAS GGPHRCTICR RGFATGQALG GHKRCHYWDG MPVSVSVSAS ASVSASGGTG 180 SFGVTVRNFD LNLTPLAGE

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Sof.16294	0.0	root

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in abscisic acid (ABA) signaling. Required for the regulation of the cross-talk between NADPH oxidase, hydrogen peroxide and MAP kinase in ABA signaling. Regulates the expression of the NADPH oxidase genes RBOHB and RBOHE, and the MAPK genes MPK1, MPK4, MPK5, MPK7 and MPK14. Regulates ABA-induced hydrogen peroxide production and antioxidant defense. Required for tolerance to water stress and oxidative stress. {ECO:0000269\|PubMed:25071223}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by abscisic acid (ABA) and hydrogen peroxide. {ECO:0000269\|PubMed:25071223}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002465091.2	4e-77	uncharacterized protein LOC8063219
Refseq	XP_008657294.1	8e-79	zinc finger protein 36
Swissprot	Q75KE5	2e-58	ZFP36_ORYSJ; Zinc finger protein 36
TrEMBL	C5WVL9	7e-81	C5WVL9_SORBI; Uncharacterized protein
STRING	Sb01g031900.1	1e-81	(Sorghum bicolor)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G49930.1	2e-22	C2H2 family protein

Publications ? help Back to Top
Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764] Yilmaz A, et al. GRASSIUS: a platform for comparative regulatory genomics across the grasses. Plant Physiol., 2009. 149(1): p. 171-80 [PMID:18987217] Zhang H, et al. A novel rice C2H2-type zinc finger protein, ZFP36, is a key player involved in abscisic acid-induced antioxidant defence and oxidative stress tolerance in rice. J. Exp. Bot., 2014. 65(20): p. 5795-809 [PMID:25071223] Li W, et al. A Natural Allele of a Transcription Factor in Rice Confers Broad-Spectrum Blast Resistance. Cell, 2017. 170(1): p. 114-126.e15 [PMID:28666113]