PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum

Family

MYB

Protein Properties

Length: 273aa MW: 29951.4 Da PI: 5.6401

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sobic.006G148000.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	51.3	2.8e-16	14	61	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT+eEd++lv+ ++ +G +W++ ++ g+ R++k+c++rw +yl Sobic.006G148000.1.p 14 KGPWTPEEDKILVNHIQSFGHSNWRALPKQAGLLRCGKSCRLRWINYL 61 79****************************99**********97 PP
2	Myb_DNA-binding	52.2	1.4e-16	67	112	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg++++eE++ ++ +++qlG++ W++Ia++++ gRt++++k+ w+++l Sobic.006G148000.1.p 67 RGNFSKEEEDAIITLHEQLGNR-WSAIAARLP-GRTDNEIKNVWHTHL 112 89******************.*****.**********986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	5.0E-25	5	64	IPR009057	Homeodomain-like
PROSITE profile	PS51294	14.878	9	61	IPR017930	Myb domain
SuperFamily	SSF46689	3.67E-30	10	108	IPR009057	Homeodomain-like
SMART	SM00717	7.2E-13	13	63	IPR001005	SANT/Myb domain
Pfam	PF00249	1.2E-14	14	61	IPR001005	SANT/Myb domain
CDD	cd00167	1.33E-10	16	61	No hit	No description
PROSITE profile	PS51294	25.178	62	116	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	2.0E-26	65	116	IPR009057	Homeodomain-like
SMART	SM00717	3.6E-15	66	114	IPR001005	SANT/Myb domain
Pfam	PF00249	4.2E-15	67	112	IPR001005	SANT/Myb domain
CDD	cd00167	1.20E-11	69	112	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 273 aa Download sequence Send to blast
MGRAPCCEKM GLKKGPWTPE EDKILVNHIQ SFGHSNWRAL PKQAGLLRCG KSCRLRWINY 60 LRPDIKRGNF SKEEEDAIIT LHEQLGNRWS AIAARLPGRT DNEIKNVWHT HLKKRLEPTT 120 KPEEQHGAQA GGAGKKHRPK RGAAKKTTAD DVAVVPATTA PVSPERSPAS SSVTESSSMT 180 EQEQEQGNTG SSAGGFPIKE ESFTSSASDA EEFQFDDTFW SETLSMPLES FDVPMEPYDA 240 LGASSVGADG DLDYWLGVFM ESGDVHQELP QI*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h8a_C	2e-26	12	116	25	128	MYB TRANSFORMING PROTEIN
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Sbi.3364	0.0	callus\| leaf

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in cold stress response (PubMed:14675437, PubMed:20807373, PubMed:22246661). Regulates positively the expression of genes involved in reactive oxygen species (ROS) scavenging such as peroxidase and superoxide dismutase during cold stress. Transactivates a complex gene network that have major effects on stress tolerance and panicle development (PubMed:20807373). {ECO:0000269\|PubMed:14675437, ECO:0000269\|PubMed:20807373, ECO:0000269\|PubMed:22246661}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Sobic.006G148000.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By cold stress. {ECO:0000269\|PubMed:14675437, ECO:0000269\|PubMed:20807373, ECO:0000269\|Ref.2}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT039884	0.0	BT039884.1 Zea mays full-length cDNA clone ZM_BFc0049A07 mRNA, complete cds.
GenBank	HQ858709	0.0	HQ858709.1 Zea mays clone UT1165 MYB transcription factor mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002448188.1	0.0	transcription factor MYB4
Swissprot	Q7XBH4	1e-108	MYB4_ORYSJ; Transcription factor MYB4
TrEMBL	C5YCC8	0.0	C5YCC8_SORBI; Uncharacterized protein
STRING	Sb06g022660.1	0.0	(Sorghum bicolor)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP79	38	563
Representative plant	OGRP5	17	1784

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23250.1	8e-77	myb domain protein 15

Link Out ? help Back to Top
Phytozome	Sobic.006G148000.1.p
Entrez Gene	8075933

Publications ? help Back to Top
Park MR, et al. Supra-optimal expression of the cold-regulated OsMyb4 transcription factor in transgenic rice changes the complexity of transcriptional network with major effects on stress tolerance and panicle development. Plant Cell Environ., 2010. 33(12): p. 2209-30 [PMID:20807373] Soltész A, et al. The rice Osmyb4 gene enhances tolerance to frost and improves germination under unfavourable conditions in transgenic barley plants. J. Appl. Genet., 2012. 53(2): p. 133-43 [PMID:22246661] H The R2R3-MYB transcription factors MYB14 and MYB15 regulate stilbene biosynthesis in Vitis vinifera. Plant Cell, 2013. 25(10): p. 4135-49 [PMID:24151295]