PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum

Family

C2H2

Protein Properties

Length: 147aa MW: 15316.3 Da PI: 8.6975

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sobic.001G035300.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	12	0.00062	41	63	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C+ C+++F++ L H +H Sobic.001G035300.1.p 41 FECKTCNRRFPSFQALGGHRASH 63 89**********99999998887 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	8.17E-8	39	103	No hit	No description
Pfam	PF13912	2.8E-13	40	65	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.13	41	63	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.18	41	68	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	43	63	IPR007087	Zinc finger, C2H2
Pfam	PF13912	1.1E-8	80	105	IPR007087	Zinc finger, C2H2
SMART	SM00355	7.8	81	103	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	8.517	81	108	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	83	103	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 147 aa Download sequence Send to blast
MKRLTFGQQE QEPGVISVAQ GVMLLLARSG GGEPSASPRV FECKTCNRRF PSFQALGGHR 60 ASHKRPRAAD AAAAPAKARA HGCAVCGVEF ALGQALGGHM RRHRAVAEGE ERDGAASAHG 120 LDLHDAEAKP EEARGLLGFD LNIAPS*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, stems and flowers. {ECO:0000269\|PubMed:9132053}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor involved in light acclimation, cold and oxidative stress responses. May regulate a collection of transcripts involved in response to high-light, cold and oxidative stress. {ECO:0000269\|PubMed:11069694, ECO:0000269\|PubMed:14722088, ECO:0000269\|PubMed:15634197, ECO:0000269\|PubMed:16183833}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Sobic.001G035300.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By H(2)O(2), cold, drought, cold or heat stresses, wounding, cucumber mosaic virus (CMV), exposure to high-intensity light and low-oxygen conditions in roots. {ECO:0000269\|PubMed:12368499, ECO:0000269\|PubMed:14722088, ECO:0000269\|PubMed:15634197, ECO:0000269\|PubMed:16183833, ECO:0000269\|PubMed:18201973, ECO:0000269\|PubMed:18922600}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002463629.1	1e-100	zinc finger protein ZAT12
Swissprot	Q42410	1e-24	ZAT12_ARATH; Zinc finger protein ZAT12
TrEMBL	C5WV19	4e-99	C5WV19_SORBI; Uncharacterized protein
STRING	Sb01g003300.1	1e-100	(Sorghum bicolor)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP501	37	157
Representative plant	OGRP131	15	149

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G46080.1	2e-22	C2H2 family protein

Link Out ? help Back to Top
Phytozome	Sobic.001G035300.1.p
Entrez Gene	8057370

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Shi H,Chan Z The cysteine2/histidine2-type transcription factor ZINC FINGER OF ARABIDOPSIS THALIANA 6-activated C-REPEAT-BINDING FACTOR pathway is essential for melatonin-mediated freezing stress resistance in Arabidopsis. J. Pineal Res., 2014. 57(2): p. 185-91 [PMID:24962049] Munekage YN,Inoue S,Yoneda Y,Yokota A Distinct palisade tissue development processes promoted by leaf autonomous signalling and long-distance signalling in Arabidopsis thaliana. Plant Cell Environ., 2015. 38(6): p. 1116-26 [PMID:25293694] Le CT, et al. ZINC FINGER OF ARABIDOPSIS THALIANA12 (ZAT12) Interacts with FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (FIT) Linking Iron Deficiency and Oxidative Stress Responses. Plant Physiol., 2016. 170(1): p. 540-57 [PMID:26556796] Ben Daniel BH, et al. Identification of novel transcriptional regulators of Zat12 using comprehensive yeast one-hybrid screens. Physiol Plant, 2016. 157(4): p. 422-41 [PMID:26923089] Tang Y, et al. Oxidative stress-induced toxicity of CuO nanoparticles and related toxicogenomic responses in Arabidopsis thaliana. Environ. Pollut., 2016. 212: p. 605-614 [PMID:27016889] Corrales AR, et al. Multifaceted role of cycling DOF factor 3 (CDF3) in the regulation of flowering time and abiotic stress responses in Arabidopsis. Plant Cell Environ., 2017. 40(5): p. 748-764 [PMID:28044345] Xu J,Tran T,Padilla Marcia CS,Braun DM,Goggin FL Superoxide-responsive gene expression in Arabidopsis thaliana and Zea mays. Plant Physiol. Biochem., 2017. 117: p. 51-60 [PMID:28587993] Nguyen HM, et al. Ethanol Enhances High-Salinity Stress Tolerance by Detoxifying Reactive Oxygen Species in Arabidopsis thaliana and Rice. Front Plant Sci, 2017. 8: p. 1001 [PMID:28717360]