PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sme2.5_04752.1_g00001.1
Organism
Solanum melongena
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
Family HD-ZIP
Protein Properties Length: 835aa    MW: 91373.1 Da    PI: 6.4613
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sme2.5_04752.1_g00001.1genomeEGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox57.62.1e-182583357
                             --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
                 Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                             k  ++t+eq+e+Le++++++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  Sme2.5_04752.1_g00001.1 25 KYVRYTTEQVEALERVYAECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 83
                             5678*****************************************************97 PP
2START27.37.6e-10164222260
                              HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHH CS
                    START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlal 60 
                              +aee+++e+++ka+ ++  Wv ++ +++g++++ +f+ s+++sg a+ra+g+v  ++a+
  Sme2.5_04752.1_g00001.1 164 IAEETLTEFLSKATGTAVDWVPMPGMKPGPDSVGIFAISHSCSGVAARACGLVNLEPAK 222
                              789***************************************************99986 PP
3START113.82.5e-3625941058204
                              HHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--... CS
                    START  58 lallveellddkeqWdetlakaetlevissg..galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe.. 138
                              ++   +e+l+d++ W ++++ +e+    s g  g+++l +++ +a+++l+p Rdf+++Ry+ +l  g++v++++S++ +   p+  
  Sme2.5_04752.1_g00001.1 259 PT-KIAEVLKDRPSWFRDCRNVEVFTMFSAGngGTVELLYTQIYAPTTLAPaRDFWTLRYTTTLDNGSLVVCERSLSGTGAGPNpa 343
                              44.7899999999****************9999********************************************999999888 PP

                              .-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHHHHHHHHHHHHHHHHTXXXX CS
                    START 139 .sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslvksglaegaktwvatlqrqc 204
                                s++vRa++lpSg+li+p+++g+s +++v+h +l++++ +++lr+l++s+ + ++k++ a+l++ +
  Sme2.5_04752.1_g00001.1 344 sASQFVRAQMLPSGYLIRPCDGGGSIIHIVDHLNLEAWSAPEILRPLYESSKVVAQKMTIAALRYAR 410
                              999************************************************************9876 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.602.7E-18883IPR009057Homeodomain-like
PROSITE profilePS5007115.4672084IPR001356Homeobox domain
SuperFamilySSF466891.75E-162186IPR009057Homeodomain-like
SMARTSM003891.7E-152288IPR001356Homeobox domain
CDDcd000864.64E-162585No hitNo description
PfamPF000466.8E-162683IPR001356Homeobox domain
CDDcd146864.82E-677116No hitNo description
PROSITE profilePS5084825.927154421IPR002913START domain
SuperFamilySSF559613.61E-28159217No hitNo description
SMARTSM002345.1E-25163412IPR002913START domain
PfamPF018521.3E-6164223IPR002913START domain
Gene3DG3DSA:3.30.530.204.5E-17165190IPR023393START-like domain
Gene3DG3DSA:3.30.530.204.5E-17231407IPR023393START-like domain
SuperFamilySSF559613.61E-28257414No hitNo description
PfamPF018522.2E-33260410IPR002913START domain
PfamPF086701.6E-48690834IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009855Biological Processdetermination of bilateral symmetry
GO:0009944Biological Processpolarity specification of adaxial/abaxial axis
GO:0009956Biological Processradial pattern formation
GO:0010014Biological Processmeristem initiation
GO:0010051Biological Processxylem and phloem pattern formation
GO:0010089Biological Processxylem development
GO:0030154Biological Processcell differentiation
GO:0005634Cellular Componentnucleus
GO:0008289Molecular Functionlipid binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 835 aa     Download sequence    Send to blast
MAMVAQQHRE SSSGSITKHL DSSGKYVRYT TEQVEALERV YAECPKPSSL RRQQLIRECP  60
ILSNIEPKQI KVWFQNRRCR EKQRKESSRL QTVNRKLSAM NKLLMEENDR LQKQVSQLVC  120
ENGYMRQQLQ NASAATTDVS CESVVTTPQH SLRDANNPAG LLSIAEETLT EFLSKATGTA  180
VDWVPMPGMK PGPDSVGIFA ISHSCSGVAA RACGLVNLEP AKITMFSTGS GGIIAEILKD  240
RLTGDLAKSA DSDVSSLEPT KIAEVLKDRP SWFRDCRNVE VFTMFSAGNG GTVELLYTQI  300
YAPTTLAPAR DFWTLRYTTT LDNGSLVVCE RSLSGTGAGP NPASASQFVR AQMLPSGYLI  360
RPCDGGGSII HIVDHLNLEA WSAPEILRPL YESSKVVAQK MTIAALRYAR QLAQETSGEV  420
VYGLGRQPAV LRTFSQRLCR GFNDAINGFS DDGWSMLSSD GAEDVIVAVN SRKNLATTSI  480
PLSPLGGILC AKASMLLQNV PPAVLVRFLR EHRSEWADFN VDAFVASALK SCPYTYPGMR  540
PTRFTGSQII MPLGHTIEHE EMLEVIRLEG HSIGQEDAFM PRDIHLLQSD APDTLNAHRT  600
LDLASSLEVG PATSSAAGDA ASCYSARSVL TIAFQFPYED NLQDNVATMA RQYVRSVVSS  660
VQRVAMAISP TGVNPSLGAK LSPGSPEAVT LSHWICQSYS YHMGTDLLRT DSSGDESVLK  720
NLWQHQDAIL CCSLKSLPVF IFANKAGLDM LETTLVALQD ISLDKIFDES GRKVLFSEFP  780
KIMEQGFACL PGGICMSAMG RHISYEQAIA WKVFAASEEN AVHCLAFSFI NWSFV
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of interfascicular fiber (cortical cells) and secondary xylem differentiation in the inflorescence stems. Required for lateral shoot meristems (LSMs) and flower meristems (FMs) initiation. May be involved in the determination of vascular patterning and organ polarity (PubMed:10559440, PubMed:11169198, PubMed:11402186, PubMed:15111711, PubMed:15598805, PubMed:7555701). Directly regulates the expression of AGO10, ZPR1, ZPR2, ZPR3 and ZPR4 (PubMed:22781836). Required to regulate adaxial-abaxial polarity and leaf axial patterning (PubMed:20807212). {ECO:0000269|PubMed:10559440, ECO:0000269|PubMed:11169198, ECO:0000269|PubMed:11402186, ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:15598805, ECO:0000269|PubMed:20807212, ECO:0000269|PubMed:22781836, ECO:0000269|PubMed:7555701}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by ZPR and miR165. Induced by DOF5.1 (PubMed:20807212). {ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:20807212}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0135770.0BT013577.1 Lycopersicon esculentum clone 132322R, mRNA sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016547131.10.0PREDICTED: homeobox-leucine zipper protein REVOLUTA
SwissprotQ9SE430.0REV_ARATH; Homeobox-leucine zipper protein REVOLUTA
TrEMBLA0A2G2YHP90.0A0A2G2YHP9_CAPAN; Homeobox-leucine zipper protein HOX10
STRINGSolyc11g069470.1.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA45724140
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60690.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Lian H,Li X,Liu Z,He Y
    HYL1 is required for establishment of stamen architecture with four microsporangia in Arabidopsis.
    J. Exp. Bot., 2013. 64(11): p. 3397-410
    [PMID:23918970]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  4. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  5. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  6. Shi B, et al.
    Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis.
    PLoS Genet., 2016. 12(7): p. e1006168
    [PMID:27398935]