PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum

Family

HD-ZIP

Protein Properties

Length: 282aa MW: 31495.4 Da PI: 6.2698

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sme2.5_01515.1_g00005.1	genome	EGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	58.5	1.2e-18	125	179	2	56
T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 rk+ +++keq +Lee F+++++++ +++ LAk+l+L rqV vWFqNrRa+ k Sme2.5_01515.1_g00005.1 125 RKKLRLSKEQAAVLEETFKEHNTLNPKQKLALAKQLNLRPRQVEVWFQNRRARTK 179 788899***********************************************98 PP
2	HD-ZIP_I/II	128	4.1e-41	125	214	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekevee 86 +kk+rlskeq+++LEe+F+e+++L+p++K +la++L+l+prqv+vWFqnrRARtk+kq+E+d+e+Lkr++++l+een+rL+kev+e Sme2.5_01515.1_g00005.1 125 RKKLRLSKEQAAVLEETFKEHNTLNPKQKLALAKQLNLRPRQVEVWFQNRRARTKLKQTEVDCEYLKRCCETLTEENRRLQKEVSE 210 69************************************************************************************ PP HD-ZIP_I/II 87 Lreel 91 Lr +l Sme2.5_01515.1_g00005.1 211 LR-AL 214 *9.55 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04618	4.3E-13	3	101	IPR006712	HD-ZIP protein, N-terminal
SuperFamily	SSF46689	1.97E-18	120	182	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.281	121	181	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	7.0E-18	121	184	IPR009057	Homeodomain-like
SMART	SM00389	2.1E-15	123	185	IPR001356	Homeobox domain
CDD	cd00086	2.44E-15	125	182	No hit	No description
Pfam	PF00046	3.7E-16	125	179	IPR001356	Homeobox domain
PROSITE pattern	PS00027	0	156	179	IPR017970	Homeobox, conserved site
SMART	SM00340	2.8E-26	181	224	IPR003106	Leucine zipper, homeobox-associated
Pfam	PF02183	6.5E-11	181	215	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 282 aa Download sequence Send to blast
MSGEKEDGLG LSLSLGIMSS PQKTLKNDFT LNLLPFMNHH QISSGRKDEE GERVRGDIDM 60 NEPARMILEC DNVEEEEEED QVIMVSSPNS TVSSVSGKRS HEREENEGER ATSSLEDDGG 120 DAAARKKLRL SKEQAAVLEE TFKEHNTLNP KQKLALAKQL NLRPRQVEVW FQNRRARTKL 180 KQTEVDCEYL KRCCETLTEE NRRLQKEVSE LRALKLSPQL YMNMSPPTTL TMCPQCERVA 240 VSSSSSSAVS SSVTGASASR SHHQAPVPLN KSWAAILAPK TL

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	173	181	RRARTKLKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By transition from light to far-red light. {ECO:0000269\|PubMed:8106086}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT013613	0.0	BT013613.1 Lycopersicon esculentum clone 132414F, mRNA sequence.
GenBank	X91212	0.0	X91212.1 L.esculentum mRNA for HD-ZIP protein.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001234233.1	1e-158	HD-ZIP protein
Refseq	XP_015065330.1	1e-158	homeobox-leucine zipper protein HAT3-like
Swissprot	P92953	3e-82	ATHB4_ARATH; Homeobox-leucine zipper protein ATHB-4
TrEMBL	Q42437	1e-157	Q42437_SOLLC; HD-ZIP protein
STRING	Solyc01g090460.2.1	1e-158	(Solanum lycopersicum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1118	24	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G60390.1	2e-62	homeobox-leucine zipper protein 3

Publications ? help Back to Top
Carabelli M,Turchi L,Ruzza V,Morelli G,Ruberti I Homeodomain-Leucine Zipper II family of transcription factors to the limelight: central regulators of plant development. Plant Signal Behav, 2014. [PMID:23838958] Francisco M, et al. Genome Wide Association Mapping in Arabidopsis thaliana Identifies Novel Genes Involved in Linking Allyl Glucosinolate to Altered Biomass and Defense. Front Plant Sci, 2016. 7: p. 1010 [PMID:27462337] Gallemí M, et al. A non-DNA-binding activity for the ATHB4 transcription factor in the control of vegetation proximity. New Phytol., 2017. 216(3): p. 798-813 [PMID:28805249]