PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sme2.5_01489.1_g00005.1
Organism
Solanum melongena
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
Family HD-ZIP
Protein Properties Length: 708aa    MW: 78026.8 Da    PI: 6.7089
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sme2.5_01489.1_g00005.1genomeEGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox60.23.3e-193081556
                             SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
                 Homeobox  5 ttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                             +++t++q++ Le++F+++++p++++r +L++ lgL  rq+k+WFqNrR++ k
  Sme2.5_01489.1_g00005.1 30 HRHTAHQIQSLEAVFKECPHPDEKMRLQLSRDLGLAPRQIKFWFQNRRTQLK 81
                             689*********************************************9987 PP
2START161.75.3e-512234482206
                              HHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S CS
                    START   2 laeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla 77 
                              +a  a++el+++ + +ep+W+ks     + ++ d + q+f+++++       ++ea+r sgvv+m+ + lv  ++d++ +W e ++
  Sme2.5_01489.1_g00005.1 223 IAANAMEELIRLLQTNEPLWTKSTtdgrDVLDIDNYHQIFPKANSslknqnVRVEASRQSGVVIMNGVALVDMFMDVN-KWVEFFP 307
                              67889***********************9***********999999***999**************************.******* PP

                              ....EEEEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEE CS
                    START  78 ....kaetlevissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgi 152
                                  +a tlevis g      ++lql + e q+lsplvp R  +f+R+++q +  +w++vdvS d+++++ + +s+ ++++lpSg+
  Sme2.5_01489.1_g00005.1 308 tivsRARTLEVISCGlmggrsSTLQLLYEEQQVLSPLVPtRQLYFLRFCQQIEPCSWAVVDVSYDVTRENLSPPSSSKVHKLPSGC 393
                              *********************************************************************988999*********** PP

                              EEEEECTCEEEEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
                    START 153 liepksnghskvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                              li++++ng+skvtw+ehv+++++   h l+r l+ sg+a+ga +w+  lqr+ce+
  Sme2.5_01489.1_g00005.1 394 LIQDMPNGYSKVTWLEHVEVEEKGSiHRLFRDLIYSGVAFGAERWLGSLQRLCER 448
                              ********************998666***************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466894.6E-191383IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.0E-201477IPR009057Homeodomain-like
PROSITE profilePS5007117.1842383IPR001356Homeobox domain
SMARTSM003892.8E-192487IPR001356Homeobox domain
CDDcd000867.83E-182584No hitNo description
PfamPF000467.8E-173081IPR001356Homeobox domain
PROSITE patternPS0002705881IPR017970Homeobox, conserved site
PROSITE profilePS5084847.171213451IPR002913START domain
SuperFamilySSF559613.97E-34214450No hitNo description
CDDcd088752.42E-111217447No hitNo description
SMARTSM002342.8E-37222448IPR002913START domain
PfamPF018526.2E-43223448IPR002913START domain
SuperFamilySSF559614.71E-20469673No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 708 aa     Download sequence    Send to blast
MEFGAEGGGG AASSSGVDAS DAHRKKKRFH RHTAHQIQSL EAVFKECPHP DEKMRLQLSR  60
DLGLAPRQIK FWFQNRRTQL KSQHERADNS ALRSENDRIR CENIAIREAI KNVICPSCGG  120
PPEDTYFDEQ KLRMENLQLK AELDKISSIA AKYMGRPISQ LPPVQPIHLS SLNLMSMSNF  180
GLTGPSLDLD LDLIPASTTT TFPNLPCPAL KISDMDKSLM ADIAANAMEE LIRLLQTNEP  240
LWTKSTTDGR DVLDIDNYHQ IFPKANSSLK NQNVRVEASR QSGVVIMNGV ALVDMFMDVN  300
KWVEFFPTIV SRARTLEVIS CGLMGGRSST LQLLYEEQQV LSPLVPTRQL YFLRFCQQIE  360
PCSWAVVDVS YDVTRENLSP PSSSKVHKLP SGCLIQDMPN GYSKVTWLEH VEVEEKGSIH  420
RLFRDLIYSG VAFGAERWLG SLQRLCERYA CLMVSGNSSR ELGGVIPSPE GKKSMMKVAQ  480
RMVSSFCASI NPSNGHQWNN ISTLDEFEVR ATLQKCTDPG QPNGVVISAA STIWLPVPPQ  540
HVFNFLRDEG TRPQWDVLSN QNPVQEVAHI ANGSHPGNSI SVLRAYNTSQ NNMLILQESC  600
IDSSGSLVVY SPVDLQSINI AMSGEDTTYI PLLPSGFTIL PDGRKESSMN NGSMGAGGGG  660
SLVTVVFQIL VSSLSSSTKM SPESVNTVNN LIGNTIHQIK AALNCSTS
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9754451e-165HG975445.1 Solanum pennellii chromosome ch06, complete genome.
GenBankHG9755181e-165HG975518.1 Solanum lycopersicum chromosome ch06, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004241474.10.0homeobox-leucine zipper protein HDG11-like
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A3Q7H1K20.0A0A3Q7H1K2_SOLLC; Uncharacterized protein
STRINGSolyc06g072310.2.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24902351
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]