PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum

Family

Dof

Protein Properties

Length: 288aa MW: 31920.4 Da PI: 6.7706

Description

Dof family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sme2.5_00536.1_g00017.1	genome	EGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-Dof	127	5.7e-40	53	113	2	62
zf-Dof 2 kekalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPvGggrrknkkss 62 +++ l+cprCdst+tkfCyynnyslsqPryfCk+CrryWtkGG+lrn+PvGgg+rknkk+s Sme2.5_00536.1_g00017.1 53 HDQPLNCPRCDSTHTKFCYYNNYSLSQPRYFCKSCRRYWTKGGTLRNIPVGGGCRKNKKHS 113 7899******************************************************987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
ProDom	PD007478	1.0E-27	51	107	IPR003851	Zinc finger, Dof-type
Pfam	PF02701	1.6E-33	54	111	IPR003851	Zinc finger, Dof-type
PROSITE profile	PS50884	29.208	57	111	IPR003851	Zinc finger, Dof-type
PROSITE pattern	PS01361	0	59	95	IPR003851	Zinc finger, Dof-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010067	Biological Process	procambium histogenesis
GO:0010087	Biological Process	phloem or xylem histogenesis
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 288 aa Download sequence Send to blast
MGITSLQVCM DSSNWLQDTI PEEVEFDSSS SPSGGDIFTC TRPLMEKKLR PQHDQPLNCP 60 RCDSTHTKFC YYNNYSLSQP RYFCKSCRRY WTKGGTLRNI PVGGGCRKNK KHSSKKISND 120 NTTPHVESSN NNYPEVAFSH FGNFMGNNNF MHHAPIEFME SKYEALVGTT TSTRNQDFIG 180 NVNVATIDGY GEMDNSGIGP NYHGGVYSST FGLGNMDGNI INYEGQNITM DVKPNPKILS 240 LEWHDQGCSN YSGNIKESFG YLSTGGLGTW TGLMNNGYGS SAMTNSLV

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Promotes expression (PubMed:19915089). The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements (PubMed:30626969). Involved in the regulation of interfascicular cambium formation and vascular tissue development, particularly at a very early stage during inflorescence stem development; promotes both cambium activity and phloem specification, but prevents xylem specification (PubMed:19915089). {ECO:0000250\|UniProtKB:Q9M2U1, ECO:0000269\|PubMed:19915089, ECO:0000269\|PubMed:30626969}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00580	DAP	Transfer from AT5G62940	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975445	0.0	HG975445.1 Solanum pennellii chromosome ch06, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015077846.1	1e-162	dof zinc finger protein DOF5.6
Swissprot	Q9FM03	8e-50	DOF56_ARATH; Dof zinc finger protein DOF5.6
TrEMBL	A0A1U8H0F2	1e-154	A0A1U8H0F2_CAPAN; Uncharacterized protein
TrEMBL	A0A2G2WM24	1e-154	A0A2G2WM24_CAPBA; Dof zinc finger protein PBF
TrEMBL	A0A2G2ZCK9	1e-154	A0A2G2ZCK9_CAPAN; dof zinc finger protein DOF5.6-like
STRING	PGSC0003DMT400069680	1e-153	(Solanum tuberosum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA4895	22	40

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G62940.1	3e-45	Dof family protein

Publications ? help Back to Top
Miyashima S, et al. Mobile PEAR transcription factors integrate positional cues to prime cambial growth. Nature, 2019. 565(7740): p. 490-494 [PMID:30626969]