PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria

Family

MYB

Protein Properties

Length: 247aa MW: 26731.3 Da PI: 8.1038

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sevir.2G082000.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	22.1	3.6e-07	27	56	19	48
TTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 19 lGggtWktIartmgkgRtlkqcksrwqkyl 48 G +W ++++ g+ R++k+c++rw +yl Sevir.2G082000.1.p 27 NGQCCWGAVPKLAGLLRCGKSCRLRWTNYL 56 45559*******99**********97 PP
2	Myb_DNA-binding	26.2	1.9e-08	65	100	4	47
S-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 4 WTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 ++eE++ ++++++lG++ ++ gRt++++k++w+++ Sevir.2G082000.1.p 65 LSPEEEKTVINLHAELGNR-------PLP-GRTDNDIKNHWNTH 100 69*************99.......688.**********97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF00249	1.7E-5	27	56	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	8.3E-11	27	63	IPR009057	Homeodomain-like
SuperFamily	SSF46689	1.2E-15	43	110	IPR009057	Homeodomain-like
PROSITE profile	PS51294	18.255	57	105	IPR017930	Myb domain
SMART	SM00717	9.4E-4	61	103	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	8.3E-15	64	105	IPR009057	Homeodomain-like
Pfam	PF00249	1.3E-6	65	100	IPR001005	SANT/Myb domain
CDD	cd00167	1.16E-6	66	101	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 247 aa Download sequence Send to blast
MGRQPCCDKV GGHGRRRRTR SSFLVNNGQC CWGAVPKLAG LLRCGKSCRL RWTNYLRPDL 60 KRGLLSPEEE KTVINLHAEL GNRPLPGRTD NDIKNHWNTH IKKKLRKMGI DPATHKPLQP 120 APPQPNEEEK AAAASAIVSG VELGNEAFSI SEVPMVHLLD DVVLPYDLVA GAPPASNSGI 180 DTAYSPEPSS SSSSCSGSAT VSSCASSVVD GVPGLAGSRC CWTPWTFEDP FVTYQRIALF 240 DHQETW*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1a5j_A	9e-15	28	105	26	108	B-MYB
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as positive regulator of abscisic acid (ABA) signaling in response to salt stress. Acts as negative regulator ABI1, ABI2 and PP2CA, which are protein phosphatases 2C acting as negative regulator of ABA signaling. Binds to the DNA specific sequence and core element 5'-ACGT-3' found in the promoters of ABI1 and PP2CA to negatively regulate their expression during ABA-dependent salt stress response. {ECO:0000269\|PubMed:23660402}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Sevir.2G082000.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by salt stress, drought stress and abscisic acid (ABA). Down-regulated by salicylic acid (SA) methyl jasmonate (JA). {ECO:0000269\|PubMed:23660402}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK367390	2e-53	AK367390.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv2056F10.
GenBank	AK375263	2e-53	AK375263.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv3089G21.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004956764.1	1e-125	transcription factor MYB41
Swissprot	Q9C7U7	8e-61	MYB20_ARATH; Transcription factor MYB20
TrEMBL	K4A0V7	1e-124	K4A0V7_SETIT; Uncharacterized protein
STRING	Si032498m	1e-125	(Setaria italica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP79	38	563

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G66230.1	1e-60	myb domain protein 20

Link Out ? help Back to Top
Phytozome	Sevir.2G082000.1.p

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546]