PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria

Family

C2H2

Protein Properties

Length: 434aa MW: 46661.8 Da PI: 6.5049

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Seita.2G251800.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	15.8	4e-05	249	268	1	20
EEETTTTEEESSHHHHHHHH CS zf-C2H2 1 ykCpdCgksFsrksnLkrHi 20 ++Cp C k+F+r n++ H+ Seita.2G251800.1.p 249 FSCPVCFKTFNRYNNMQMHM 268 89*****************9 PP
2	zf-C2H2	10.9	0.0014	335	355	3	23
ETTTTEEESSHHHHHHHHHHT CS zf-C2H2 3 CpdCgksFsrksnLkrHirtH 23 C Cgk F k + ++H +++ Seita.2G251800.1.p 335 CRRCGKAFAVKGDWRTHEKNC 355 *****************9987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50157	9.64	249	276	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	6.5E-6	249	268	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	251	271	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	3.58E-6	315	353	No hit	No description
Gene3D	G3DSA:3.30.160.60	4.1E-5	320	353	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	8.538	333	353	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 434 aa Download sequence Send to blast
MENPYTSFFK RHPHHHRYYY HPPAPRASGP PPAAAYSSLP FFAAHLQPPA QEAPPAPPSP 60 PLREALPLLS LVPAASRGAA REPERRGRAA ALDSDEDGDE EEEEEEGPAA SSSIHHGHGQ 120 QQRLGGLFAD LNAKAAGDPM DVEPGAGSGS AAGDVTVALR IGLPTTSAGA ADLSGTRGRR 180 DDGAEEEEDD EEGRNDRENG GGGEEEEEEE EGEAVAAPLG FPSTPIGRLN KGQYWIPTPS 240 QILIGPTQFS CPVCFKTFNR YNNMQMHMWG HGSQYRKGPE SLRGIQPTAM LRLPCYCCAP 300 GCRNNIDHPR AKPLKDFRTL QTHYKRKHGL KPFLCRRCGK AFAVKGDWRT HEKNCGRLWY 360 CLCGSEFKHK RSLKDHARAF GHGHGFVGGA GAGCGGGGLD DDDDGAVSDV EHDGVAAAAA 420 RSMCPIDRAP IRS*

Sequence ? help Back to Top

Protein Sequence Length: 434 aa Download sequence Send to blast

MENPYTSFFK RHPHHHRYYY HPPAPRASGP PPAAAYSSLP FFAAHLQPPA QEAPPAPPSP  60
PLREALPLLS LVPAASRGAA REPERRGRAA ALDSDEDGDE EEEEEEGPAA SSSIHHGHGQ  120
QQRLGGLFAD LNAKAAGDPM DVEPGAGSGS AAGDVTVALR IGLPTTSAGA ADLSGTRGRR  180
DDGAEEEEDD EEGRNDRENG GGGEEEEEEE EGEAVAAPLG FPSTPIGRLN KGQYWIPTPS  240
QILIGPTQFS CPVCFKTFNR YNNMQMHMWG HGSQYRKGPE SLRGIQPTAM LRLPCYCCAP  300
GCRNNIDHPR AKPLKDFRTL QTHYKRKHGL KPFLCRRCGK AFAVKGDWRT HEKNCGRLWY  360
CLCGSEFKHK RSLKDHARAF GHGHGFVGGA GAGCGGGGLD DDDDGAVSDV EHDGVAAAAA  420
RSMCPIDRAP IRS*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator required for normal differentiation of the ovary transmitting tract cells and pollen tube growth. In Arabidopsis, the transmitting tract facilitates the transport of pollen tubes to the ovules for fertilization (PubMed:17600712). May play a role in the regulation of AGL8/FUL, which is required for normal pattern of cell division, expansion and differentiation during morphogenesis of the silique (PubMed:23515580). Plays a role in replum development by the activation of the homeobox protein KNAT1 (PubMed:25039392). {ECO:0000269\|PubMed:17600712, ECO:0000269\|PubMed:23515580, ECO:0000269\|PubMed:25039392}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Seita.2G251800.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	EU969661	0.0	EU969661.1 Zea mays clone 333696 zinc finger protein mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004957169.1	0.0	zinc finger protein WIP2
Swissprot	Q9SVY1	1e-118	ZWIP2_ARATH; Zinc finger protein WIP2
TrEMBL	K3ZTG7	0.0	K3ZTG7_SETIT; Uncharacterized protein
STRING	Si029897m	0.0	(Setaria italica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP586	38	170

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G57670.1	1e-109	C2H2 family protein

Link Out ? help Back to Top
Phytozome	Seita.2G251800.1.p
Entrez Gene	101755479

Publications ? help Back to Top
Crawford BC, et al. Plant development. Genetic control of distal stem cell fate within root and embryonic meristems. Science, 2015. 347(6222): p. 655-9 [PMID:25612610] Boex-Fontvieille E, et al. An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence. Front Plant Sci, 2016. 7: p. 1246 [PMID:27625656]