PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Salix

Family

HSF

Protein Properties

Length: 508aa MW: 55610 Da PI: 4.5507

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SapurV1A.3823s0010.2.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	112.2	3.7e-35	37	128	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkk 88 Fl+k+y++++d++++ ++sws+++nsfvv++ ef++++LpkyFkh+nf+SFvRQLn+YgF+kv+ ++ weF+++ F + SapurV1A.3823s0010.2.p 37 FLSKTYDMVDDPATDAVVSWSSTNNSFVVWNLPEFSRDLLPKYFKHNNFSSFVRQLNTYGFRKVDPDR---------WEFANEGFLR 114 9**************************************************************999.........****** PP XXXXXXXXXXXXXX CS HSF_DNA-bind 89 gkkellekikrkks 102 g+k+ll+ i r+k SapurV1A.3823s0010.2.p 115 GQKHLLRIISRRKP 128 *********986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	2.4E-39	27	120	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	1.1E-60	33	126	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	2.04E-34	33	126	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00447	1.4E-30	37	126	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	3.6E-20	37	60	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	3.6E-20	75	87	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	76	100	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	3.6E-20	88	100	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 508 aa Download sequence Send to blast
MDGTISSASG GDASTSGGGA QAASVPMASQ SNAPPPFLSK TYDMVDDPAT DAVVSWSSTN 60 NSFVVWNLPE FSRDLLPKYF KHNNFSSFVR QLNTYGFRKV DPDRWEFANE GFLRGQKHLL 120 RIISRRKPAH GHANQQPQQP HGQNSSVAAC VEVGKFGLEE EVERLKRDKN VLMQELVRLR 180 QQQQSTDSQL QTMVQRLQGM EQRQQQMMSF LAKAMQSPSF LAQFVQQQND SNRRITEANK 240 KRRLKQEDVL ENEGSSSPDG QIVKYQPLMN EAAKGMLRQI LKMDPSSKLE SYDNNLGAKD 300 GGSSSSCTSG VTLQEVLPTL GQSTHIPAAF GISKQPTTAI SEIQSSLPIA SSEKFTASQF 360 PDISMLVGDQ GAPSLPISQA DVTMPQVSQM PEMVPENISD IPVEDYMEPE TSNGGFIDPA 420 SLGIDGIIPI DIDNISPDPD IDALLDNSSF WYDLLVQSPV PEDIESSSVE GKANGNDVQP 480 NANGWDKAQH VEQLTEQMGL LTSDKKL*

Sequence ? help Back to Top

Protein Sequence Length: 508 aa Download sequence Send to blast

MDGTISSASG GDASTSGGGA QAASVPMASQ SNAPPPFLSK TYDMVDDPAT DAVVSWSSTN  60
NSFVVWNLPE FSRDLLPKYF KHNNFSSFVR QLNTYGFRKV DPDRWEFANE GFLRGQKHLL  120
RIISRRKPAH GHANQQPQQP HGQNSSVAAC VEVGKFGLEE EVERLKRDKN VLMQELVRLR  180
QQQQSTDSQL QTMVQRLQGM EQRQQQMMSF LAKAMQSPSF LAQFVQQQND SNRRITEANK  240
KRRLKQEDVL ENEGSSSPDG QIVKYQPLMN EAAKGMLRQI LKMDPSSKLE SYDNNLGAKD  300
GGSSSSCTSG VTLQEVLPTL GQSTHIPAAF GISKQPTTAI SEIQSSLPIA SSEKFTASQF  360
PDISMLVGDQ GAPSLPISQA DVTMPQVSQM PEMVPENISD IPVEDYMEPE TSNGGFIDPA  420
SLGIDGIIPI DIDNISPDPD IDALLDNSSF WYDLLVQSPV PEDIESSSVE GKANGNDVQP  480
NANGWDKAQH VEQLTEQMGL LTSDKKL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	1e-26	18	126	10	129	Heat shock factor protein 1
5d5v_B	1e-26	18	126	10	129	Heat shock factor protein 1
5d5v_D	1e-26	18	126	10	129	Heat shock factor protein 1
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	238	245	NKKRRLKQ
2	239	244	KKRRLK

Functional Description ? help Back to Top
Source	Description
UniProt	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. {ECO:0000250}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	SapurV1A.3823s0010.2.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JF905565	0.0	JF905565.1 Populus simonii clone JL heat shock transcription factor (HsfA1d) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002303429.2	0.0	heat shock factor protein HSF8
Swissprot	Q40152	1e-167	HSF8_SOLLC; Heat shock factor protein HSF8
TrEMBL	A0A0N6WKZ7	0.0	A0A0N6WKZ7_9ROSI; Heat shock transcription factor A1c1
STRING	POPTR_0003s09370.1	0.0	(Populus trichocarpa)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G32330.1	1e-131	heat shock transcription factor A1D

Link Out ? help Back to Top
Phytozome	SapurV1A.3823s0010.2.p

Publications ? help Back to Top
Zhu B, et al. Identification and characterization of a novel heat shock transcription factor gene, GmHsfA1, in soybeans (Glycine max). J. Plant Res., 2006. 119(3): p. 247-56 [PMID:16570125] Cai SY, et al. HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants. J. Pineal Res., 2017. [PMID:28095626] Zhou J, et al. Heat Shock Factor HsfA1a Is Essential for R Gene-Mediated Nematode Resistance and Triggers H2O2 Production1. Plant Physiol., 2018. 176(3): p. 2456-2471 [PMID:29339397]