PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SapurV1A.1444s0050.1.p
Organism
Salix purpurea
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Salix
Family E2F/DP
Protein Properties Length: 442aa    MW: 48353.9 Da    PI: 4.8227
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SapurV1A.1444s0050.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.77.3e-27146211171
                 E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                             r+++sL+llt++f++l++++++gi++ln++a++L   +v  ++RRiYDi+NVLe+++liek+ kn+irwkg
  SapurV1A.1444s0050.1.p 146 RYDSSLGLLTKRFVDLFKNADDGILDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 211
                             6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.6E-28143213IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.7E-34146211IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.26E-17146209IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023194.1E-24148211IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440741.12E-30227328No hitNo description
CDDcd146601.77E-46228328No hitNo description
PfamPF164215.4E-32228326IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 442 aa     Download sequence    Send to blast
MSSGAKASTR PAATAPSSGP ILPPLTRHLA FATMKPPFVP LDDYHRFSSP STSRVATDRD  60
AEAIVVRSPQ LKRKSGLADN GVSSSNHVSS PGCSNISNSS FRAPASAKGG RTYNNSKASK  120
DNGAGPQTPV SKADCASPLT PAGSCRYDSS LGLLTKRFVD LFKNADDGIL DLNNAAETLE  180
VQKRRIYDIT NVLEGIGLIE KTLKNRIRWK GIDASRPRQV EGDATLSQAE IENLTMEEHK  240
LDDQIREMQE RLRDMSEDEN NQKWLFVTEE DIKSLPCFLN ETLIAIKAPH GTTLEVLDPD  300
EAVDCLQRRY RIILRSSMGP IDVYLVSQFE EMNSVDASAF PHASSSASNG NPVAEMTTGV  360
RTEKRGDPLE QHAQTTFSDP NGTQDLGGMM KIVPSDVNND SDYWLLSDAD ISITDMWKTD  420
SNIEWTDFEV ADVQTPRTQT L*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-22141212274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapSapurV1A.1444s0050.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024443173.10.0transcription factor E2FA isoform X2
SwissprotQ9FNY01e-154E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A2K1XC380.0A0A2K1XC38_POPTR; Uncharacterized protein
STRINGPOPTR_0016s07310.10.0(Populus trichocarpa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-148E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]