PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SapurV1A.1401s0050.2.p

Organism

Salix purpurea

Taxonomic ID

77065

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Salix

Family

E2F/DP

Protein Properties

Length: 317aa MW: 35535.7 Da PI: 4.2012

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SapurV1A.1401s0050.2.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	85.4	4.3e-27	21	86	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt++f++l++++++gi++ln++a++L +v ++RRiYDi+NVLe+++liek+ kn+irwkg SapurV1A.1401s0050.2.p 21 RYDSSLGLLTKRFVDLFKNADDGILDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 86 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	9.2E-29	18	88	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	1.9E-17	21	84	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	2.7E-34	21	86	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	2.4E-24	23	86	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF144074	5.23E-31	102	203	No hit	No description
CDD	cd14660	2.53E-45	103	203	No hit	No description
Pfam	PF16421	2.9E-32	103	201	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 317 aa Download sequence Send to blast
MNIISELADC ASPLTPAGSC RYDSSLGLLT KRFVDLFKNA DDGILDLNNA AETLEVQKRR 60 IYDITNVLEG IGLIEKTLKN RIRWKGIDAS RPRQVEGDAT LSQAEIENLT MEEHKLDDQI 120 REMQERLRDM SEDENNQKWL FVTEEDIKSL PCFLNETLIA IKAPHGTTLE VLDPDEAVDC 180 LQRRYRIILR SSMGPIDVYL VSQFEEMNSV DASAFPHASS SASNGNPVAE MTTGVRTEKR 240 GDPLEQHAQT TFSDPNGTQD LGGMMKIVPS DVNNDSDYWL LSDADISITD MWKTDSNIEW 300 TDFEVADVQT PRTQTL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	2e-23	16	87	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	SapurV1A.1401s0050.2.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011044035.1	0.0	PREDICTED: transcription factor E2FA-like isoform X2
Swissprot	Q9FNY0	1e-123	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A2K1XC38	0.0	A0A2K1XC38_POPTR; Uncharacterized protein
STRING	POPTR_0006s22150.1	0.0	(Populus trichocarpa)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-123	E2F transcription factor 3

Link Out ? help Back to Top
Phytozome	SapurV1A.1401s0050.2.p

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]