PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SapurV1A.0161s0320.1.p
Organism
Salix purpurea
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Salix
Family E2F/DP
Protein Properties Length: 385aa    MW: 43178.3 Da    PI: 8.7918
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SapurV1A.0161s0320.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP76.91.9e-242085171
                 E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                            rk+ksL+ll+++fl+l+++ +++++ l+++a++L    v  +rRRiYDi+NVLe+++++++k+kn+++wkg
  SapurV1A.0161s0320.1.p 20 RKQKSLGLLCTNFLTLYNRDDNDVIGLDDAASKL---GV--ERRRIYDIVNVLESVGVLARKAKNKYSWKG 85
                            79********************************...**..****************************98 PP
2E2F_TDP75.84.3e-24156236171
                 E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                             r+eksL+lltq+f+kl+ +s+++ ++l+e ak L+ +     ++++k+RR+YDi+NVL++l+liek     ++k+++rw g
  SapurV1A.0161s0320.1.p 156 RREKSLGLLTQNFVKLFVCSKANLISLDESAKLLLGDghnlsSMRTKVRRLYDIANVLSSLKLIEKthtadTRKPAFRWLG 236
                             689*******************************************************************99*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.2E-261686IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.86E-161983IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.3E-292085IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023194.7E-212185IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.1E-22152237IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.5E-28156236IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023195.9E-19158236IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.26E-12158237IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 385 aa     Download sequence    Send to blast
MALSYTDIID PSSRHHAYSR KQKSLGLLCT NFLTLYNRDD NDVIGLDDAA SKLGVERRRI  60
YDIVNVLESV GVLARKAKNK YSWKGFASVP KTLQELKEEG LRDNVNTIDR QTNSSAKVAN  120
DDEDEDDDED SNPNTGSQTD NSGFIKSTDV SRSDHRREKS LGLLTQNFVK LFVCSKANLI  180
SLDESAKLLL GDGHNLSSMR TKVRRLYDIA NVLSSLKLIE KTHTADTRKP AFRWLGLRGK  240
SENGSGDPLA PSESRKRTFG ADITNICFKR NKMDCSVDGD KSQNLKLQQI KDENIVTVAE  300
RGNFGQDLQQ KSGSFQFGPF APVTVAKAGN LEEKVTRIYD WEGLSTTFRP QYHNQALRDL  360
FSHYTEAWKS WYTEVAGKKP LHIS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A8e-41192283228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapSapurV1A.0161s0320.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002321561.30.0E2F transcription factor-like E2FE
SwissprotQ8LSZ41e-129E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A2K1XJ940.0A0A2K1XJ94_POPTR; Uncharacterized protein
STRINGPOPTR_0015s08160.10.0(Populus trichocarpa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-131DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]